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Preparation of new functional nanofiber composites by photografting polymerizations

Research Project

Project/Area Number 24656395
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Composite materials/Physical properties
Research InstitutionKeio University

Principal Investigator

HOTTA Atsushi  慶應義塾大学, 理工学部, 教授 (30407142)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywordsナノファイバ / 光グラフト重合 / 表面改質 / 親水性 / 生体適合性 / 医療用材料 / ステント / 複合材料 / 医療用ポリマ / ステントグラフト / ポリマー / ナノファイバー / 親水化 / 高機能化 / グラフト重合 / コンポジット
Outline of Final Research Achievements

In this research project, we amalgamated our previous research accomplishments related to “nanofibers”, “photografting polymerizations”, and “functionalization of polymers”, in order to create new functional polymeric nanofibers. As a result, by introducing hydrophilicity, we fabricated new polyurethane nanofibers with excellent elasticity and high tensile property, which would be widely used in industry. We have also succeeded in synthesizing antithrombogenic polyurethane nanofibers by introducing a highly biocompatible polymer, which would be utilized as a material for the medical applications.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (22 results)

All 2015 2014 2013 2012

All Journal Article (11 results) (of which Peer Reviewed: 11 results,  Acknowledgement Compliant: 2 results) Presentation (8 results) Book (3 results)

  • [Journal Article] Poly(2-methacryloyloxyethyl phosphorylcholine) (MPC) nanofibers coated with micro-patterned diamond-like carbon (DLC) for the controlled drug release2015

    • Author(s)
      K. Bito, T. Maeda, K. Hagiwara, S. Yoshida, T. Hasebe, A. Hotta
    • Journal Title

      Journal of Biorheology

      Volume: 未定

    • NAID

      130005100423

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Effects of Salt Concentrations of the Aqueous Peptide-Amphiphile Solutions on the Sol-Gel Transitions, the Gelation Speed, and the Gel Characteristics2014

    • Author(s)
      T. Otsuka, T. Maeda, A. Hotta
    • Journal Title

      The Journal of Physical Chemistry Part B

      Volume: 118 Issue: 39 Pages: 11537-11545

    • DOI

      10.1021/jp5031569

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Micropatterning of silica nanoparticles by electrospray deposition through a stencil mask2014

    • Author(s)
      Higashi, K., Uchida, K., Hotta, A., Hishida, K. & Miki, N.
    • Journal Title

      Journal of Laboratory Automation

      Volume: 19 Issue: 1 Pages: 75-81

    • DOI

      10.1177/2211068213495205

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Basic Fibroblast Growth Factor as a Potential Stent Coating Material Inducing Endothelial Cell Proliferation2014

    • Author(s)
      Kitamura, N., Hasebe, T., Matsumoto, T, Hotta, A., Suzuki, T., Yamagami, T. & Terada, H.
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 21 Issue: 5 Pages: 477-485

    • DOI

      10.5551/jat.20404

    • NAID

      130004444732

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Preparation and characterization of 2-methacryloyloxyethyl phosphorylcholine polymer nanofibers prepared via electrospinning for biomedical materials2014

    • Author(s)
      Maeda, T., Hagiwara, K., Yoshida, S., Hasebe, T. & Hotta, A.
    • Journal Title

      Journal of Applied Polymer Science

      Volume: 131 Issue: 14 Pages: 40606-40606

    • DOI

      10.1002/app.40606

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of salt concentrations on the structural transitions of peptide-amphiphile solution2014

    • Author(s)
      Otsuka, T. & Hotta, A.
    • Journal Title

      Materials Research Society Symposia Proceedings

      Volume: 1622 Pages: 147-152

    • DOI

      10.1557/opl.2014.40

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] The structure and the mechanical properties of a newly fabricated cellulose-nanofiber/polyvinyl-alcohol composite2014

    • Author(s)
      Oishi, Y. & Hotta, A.
    • Journal Title

      Materials Research Society Symposia Proceedings

      Volume: 1621 Pages: 149-154

    • DOI

      10.1557/opl.2014.141

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Hydrophobicity and non-thrombogenicity of nanoscale dual rough surface coated with fluorine-incorporated diamond-like carbon films: Biomimetic surface for blood-contacting medical devices2013

    • Author(s)
      Hasebe, T., Nagashima, S., Kamijo, A., Moon, M.W., Kashiwagi, Y., Hotta, A., Lee, K.R., Takahashi, K., Yamagami, T. & Suzuki, T.
    • Journal Title

      Diamond and Related Materials

      Volume: 38 Pages: 14-18

    • DOI

      10.1016/j.diamond.2013.06.001

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Improvement of gas barrier property of polyolefins by diamond-like carbon deposition and photografting polymerization2013

    • Author(s)
      Takahashi, J., Nakaya, M., Matsui, E. & Hotta, A.
    • Journal Title

      Journal of Applied Polymer Science

      Volume: - Issue: 5 Pages: 2591-2597

    • DOI

      10.1002/app.38974

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Surface modification of polymers by plasma treatments for the enhancement of biocompatibility and controlled drug release2013

    • Author(s)
      Yoshida, S., Hagiwara, K., Hasebe, T. & Hotta, A.
    • Journal Title

      Surface and Coating Technology

      Volume: - Pages: 99-107

    • DOI

      10.1016/j.surfcoat.2013.02.042

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Adhesion enhancement of polyolefins by diamond like carbon coating and photografting polymerization2012

    • Author(s)
      Takahashi, J., Hotta, A.
    • Journal Title

      Diamond and Related Materials

      Volume: Vol.26 Pages: 55-59

    • DOI

      10.1016/j.diamond.2012.04.006

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] アクリル酸モノマーの光グラフト重合によるポリウレタン ナノファイバへの機能性付与2014

    • Author(s)
      保田穣人, 堀田篤
    • Organizer
      第63回高分子討論会
    • Place of Presentation
      長崎大学文教キャンパス, 長崎
    • Year and Date
      2014-09-24 – 2014-09-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 早期内皮化促進及び抗血栓性を有するbFGF溶出性冠動脈ステントシステムの開発2014

    • Author(s)
      尾藤健太, 長谷部光泉, 堀田篤
    • Organizer
      第37回日本バイオレオロジー学会年会
    • Place of Presentation
      ソニックシティビル, 埼玉
    • Year and Date
      2014-06-05 – 2014-06-06
    • Related Report
      2014 Annual Research Report
  • [Presentation] Syndiotactic polypropylene nanofibers fabricated by a solution electrospinning method with single solvent at ambient temperature2013

    • Author(s)
      T. Maeda, K. Takaesu, A. Hotta
    • Organizer
      245th ACS National Meeting & Exposition
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] Preparation and characterization of phospholipid polymer nanofibers via electrospinning for tissue-engineered vascular grafts2013

    • Author(s)
      K. Hagiwara, A. Hotta
    • Organizer
      The 13th Pacific Polymer Conference
    • Place of Presentation
      Kaohsiung, Taiwan
    • Related Report
      2013 Research-status Report
  • [Presentation] Effects of salt concentrations on the structural transitions of peptide-amphiphile solution2013

    • Author(s)
      T. Otsuka, A. Hotta
    • Organizer
      2013 MRS Fall Meeting & Exhibit
    • Place of Presentation
      Boston, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] Solvent and temperature dependence of the one-dimensional assembly and the 3D network formation observed in silica-nanoparticle solutions2013

    • Author(s)
      A. Murano, A. Hotta
    • Organizer
      2013 MRS Fall Meeting & Exhibit
    • Place of Presentation
      Boston, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] The solution properties and the structures of newly fabricated cellulose nanofibers2013

    • Author(s)
      Y. Oishi, A. Hotta
    • Organizer
      2013 MRS Fall Meeting & Exhibit
    • Place of Presentation
      Boston, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] Enhancement of gas barrier properties of polypropylene by surface treatment before DLC coating2012

    • Author(s)
      Tashiro, H., Hotta, A.
    • Organizer
      39th ICMCTF, International Conference on Metallurgical Coating and Thin Films
    • Place of Presentation
      San Diego, USA
    • Related Report
      2012 Research-status Report
  • [Book] Comprehensive Guide for Nanocoatings Technology2015

    • Author(s)
      T. Maeda, K. Hagiwara, T. Hasebe, and A. Hotta
    • Publisher
      Nova Science Publishers
    • Related Report
      2014 Annual Research Report
  • [Book] Thin Films and Coatings in Biology2013

    • Author(s)
      A. Hotta, T. Hasebe
    • Total Pages
      365
    • Publisher
      Springer
    • Related Report
      2013 Research-status Report
  • [Book] 次世代ポリオレフィン総合研究,Vol. 72013

    • Author(s)
      前田知貴,堀田篤
    • Total Pages
      174
    • Publisher
      三恵社
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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