Development of polymeric macroporous hydrogels for the immobilization of enzymes using an emulsion-gelation method
| Project/Area Number |
24656465
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Properties in chemical engineering process/Transfer operation/Unit operation
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| Research Institution | Tokyo University of Agriculture and Technology |
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Principal Investigator |
TOKUYAMA Hideaki 東京農工大学, 工学(系)研究科(研究院), 准教授 (10363029)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 反応・分離工学 / 化学工学 / 高分子合成 / 固定化酵素 / ゲル / エマルション |
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| Research Abstract |
Novel polymeric macroporous hydrogels were developed to entrap and immobilize enzymes for improved enzyme reaction process. The emulsion-gelation method using emulsions was used to simultaneously synthesize the gels and entrap enzymes in the randomly distributed, non-interconnected, sphere-like macropores. The lipase, immobilized within the macroporous hydrogel and organogel, successfully catalyzed the hydrolysis in aqueous media and the transesterification in organic media, respectively.
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Report
(3 results)
Research Products
(12 results)
