Body on a Chip: in vitro living model using human pluripotent stem cells
| Project/Area Number |
24656502
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Kyoto University |
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Principal Investigator |
KAMEI Kenichiro 京都大学, 物質ー細胞統合システム拠点, 助教 (00588262)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | マイクロ流体デバイス / ヒト多能性幹細胞 / 組織工学 / ヒトES/iPS細胞 / 幹細胞 / Body on a Chip / 3次元微小組織 |
|---|
| Research Abstract |
In this research, we will develop "Body on a Chip" by accomplishing three aims, 1) development of microfluidic platform for construction of 3D micro tissues, 2) construction of 3D micro tissues using human pluripotent stem cells (hPSCs) and 3) development of "Body on a Chip" by interconnecting multiple 3D micro tissue within a microfluidic device.
Specifically, A. Development of high throughput microfluidic device (HT-microFD); B. Establishment of multiple 3D micro tissues within a HT-microFD using hPSCs; C. Construction of of "Body on a Chip" by interconnecting multiple 3D micro tissue within a microfluidic device.
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Report
(4 results)
Research Products
(47 results)
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[Journal Article] Microfluidic-nanofiber hybrid array for screening of cellular microenvironments2017
Author(s)
K. Kamei, Y. Mashimo, M. Yoshioka, Y. Tokunaga, C. Fockenberg, S. Terada, M. Nakajima, T. Shibata-Seki, L. Liu, T. Akaike, E. Kobatake, E. S. How, M. Uesugi and Y. Chen
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Journal Title
Small
Volume: 印刷中
Issue: 18
Pages: 1603104-1603104
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Nanofibrous gelatin substrates for long-term expansion of human pluripotent stem cells2014
Author(s)
Li Liu, Momoko Yoshioka, Minako Nakajima, Arata Ogasawara, Jun Liu, Kouichi Hasegawa, Sisi Li, Jianli Zou, Norio Nakatsuji, Ken-ichiro Kamei*, Yong Chen*
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Journal Title
Biomaterial
Volume: in press
Issue: 24
Pages: 6259-6267
DOI
Related Report
Peer Reviewed
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