• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Functional analysis of age-associated madRNA

Research Project

Project/Area Number 24657122
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Molecular biology
Research InstitutionNational Institute of Genetics

Principal Investigator

IIDA Tetsushi  国立遺伝学研究所, 細胞遺伝研究系, 助教 (60391851)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
KeywordsRNA / 老化 / ノンコーディングRNA / Webツール / 変異点同定
Research Abstract

Asymmetric cell division, "budding", produces a virgin daughter and an older mother. Rejuvenation of the daughter in budding may be from sequestration of aging factors into the mother. In this project, we found that ribonuclease-resistant RNAs are specifically accumulated into aged mother cell.
For time-consuming process of genetic analysis, we also developed a web tool for mutation identification by next-generation sequencing.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (7 results)

All 2014 2013 2012 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (2 results) Remarks (2 results)

  • [Journal Article] Mudi, a web tool for identifying mutations by bioinformatics analysis of whole-genome sequence2014

    • Author(s)
      Naoko Iida, Fumiaki Yamao, Yasukazu Nakamura, Tetsushi Iida.
    • Journal Title

      Genes to Cells

      Volume: Vol.19、No.1 Issue: 6 Pages: 517-527

    • DOI

      10.1111/gtc.12151

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Spt6 prevents transcription-coupled loss of posttranslationally modified histone H3.2013

    • Author(s)
      Kato H, Okazaki K, Iida T, Nakayama J, Murakami Y, Urano T.
    • Journal Title

      Sci Rep.

      Volume: 3 Issue: 1 Pages: 2186-2186

    • DOI

      10.1038/srep02186

    • NAID

      120006539377

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] RNA interference regulates the cell cycle checkpoint through the RNA export factor, Ptr1, in fission yeast.2012

    • Author(s)
      Iida T
    • Journal Title

      BBRC

      Volume: 427 Issue: 1 Pages: 143-147

    • DOI

      10.1016/j.bbrc.2012.09.027

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Presentation] Cell cycle regulation by RNAi components through RNA-export factor in fission yeast2012

    • Author(s)
      Tetsushi Iida, Naoko Iidab, Yasuhiro Tsutsui, Fumiaki Yamao, Takehiko Kobayashi.
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      マリンメッセ福岡・福岡
    • Related Report
      2013 Final Research Report
  • [Presentation] Cell cycle regulation by RNAi components through and RNA-expoert factor in fission yeast2012

    • Author(s)
      Tetsushi Iida, Naoko Iida, Yasuhiro Tsutsui, Fumiaki Ymao, Takehiko Kobayashi
    • Organizer
      第35回 日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡(福岡県)
    • Related Report
      2012 Research-status Report
  • [Remarks] Mudi:Mutation discovery in yeast

    • URL

      http://naoii.nig.ac.jp/mudi_top.html

    • Related Report
      2013 Final Research Report
  • [Remarks] Mudi: Mutation discovery in yeast

    • URL

      http://naoii.nig.ac.jp/mudi_top.html

    • Related Report
      2013 Annual Research Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi