• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of newt molecular genetic systems

Research Project

Project/Area Number 24657155
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Developmental biology
Research InstitutionTottori University

Principal Investigator

TAKEUCHI Takashi  鳥取大学, 医学部, 教授 (70197268)

Co-Investigator(Renkei-kenkyūsha) HAYASHI Toshinori  鳥取大学, 医学部, 准教授 (60580925)
Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords発生 / 再生 / 有尾両生類 / 分子遺伝学 / トランスジェニック / イベリアトゲイモリ / 近交系 / 純系
Research Abstract

An experimental model system for molecular genetics in newts is necessary to clarify the mechanisms of regeneration from the perspective of gene functions. We have introduced Iberian ribbed newt (Pleurodeles waltl) as the suitable model newts. In the results of our researches, we have been able to shorten the periods for sexual maturation, and are developing 2 inbred and various transgenic lines of P. waltl newts. We also demonstrated that Cre-loxP recombination system efficiently worked in the newts. In addition, we achieved targeted gene knockout in the newt using TALENs. These results show that conditional knockout newts would be available by combination of Cre-loxP recombination and TALENs. Our system would be very powerful for studying the molecular mechanisms of not only regeneration but also various researches. In relation to the result of this research, we published total 12 research and review papers, also our group had 29 conference presentations.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (81 results)

All 2014 2013 2012 Other

All Journal Article (16 results) (of which Peer Reviewed: 10 results,  Open Access: 1 results) Presentation (58 results) (of which Invited: 15 results) Book (1 results) Remarks (6 results)

  • [Journal Article] Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes2014

    • Author(s)
      Tane, S., Kubota, M., Okayama, H.,Ikenishi, A., Yoshitome, S., Iwamoto,N., Satoh, Y., Kusakabe, A., Ogawa, S.,Kanai, A., Molkentin, J. D., Nakamura, K., Ohbayashi, T., and Takeuchi, T.
    • Journal Title

      J. Biol. Chem

      Volume: (in press) Issue: 26 Pages: 18033-18044

    • DOI

      10.1074/jbc.m113.541953

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Regulation of cardiomyocyte proliferation during development and regeneration2014

    • Author(s)
      Takeuchi, T.
    • Journal Title

      Dev. Growth. Differ

      Volume: (in press) Issue: 5 Pages: 402-409

    • DOI

      10.1111/dgd.12134

    • NAID

      40020109544

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] CDK inhibitors, p21Cip1 and p27Kip1, participate in cell cycle exit of mammalian cardiomyocytes.2014

    • Author(s)
      Tane, S., Ikenishi, A., Okayama, H., Iwamoto, N., Nakayama, I. K., and Takeuchi, T.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 443 Issue: 3 Pages: 1105-1109

    • DOI

      10.1016/j.bbrc.2013.12.109

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transcription activator-like effector nucleases efficiently disrupt the target gene in Iberian ribbed newts (Pleurodeles waltl), an experimental model animal for regeneration.2014

    • Author(s)
      Hayashi T, Sakamoto K, Sakuma T, Yokotani N, Inoue T, Kawaguchi E, Agata K, Yamamoto T, Takeuchi T
    • Journal Title

      Development, Growth and Differentiation

      Volume: 56 Issue: 1 Pages: 115-121

    • DOI

      10.1111/dgd.12103

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 再生研究の革命戦士~イベリアトゲイモリの奮闘~2014

    • Author(s)
      林 利憲、竹内 隆
    • Journal Title

      細胞工学

      Volume: 33 Pages: 203-207

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] 種間による自律的な心臓再生能力の違いは何によって決まるのか?2014

    • Author(s)
      竹内 隆、林 利憲
    • Journal Title

      実験医学

      Volume: 32 Pages: 29-35

    • Related Report
      2013 Final Research Report
  • [Journal Article] Regulation of cardiomyocyte proliferation during development and regeneration.2014

    • Author(s)
      Takeuchi, T.
    • Journal Title

      Dev. Growth. Differ.

      Volume: 印刷中

    • NAID

      40020109544

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 両生類におけるTALENを用いた遺伝子改変2014

    • Author(s)
      林 利憲、坂根 祐人、竹内 隆、鈴木 賢一
    • Journal Title

      実験医学

      Volume: 別册 Pages: 180-188

    • Related Report
      2013 Annual Research Report
  • [Journal Article] 種間による自律的な心臓再生能力の違いは何によって決まるのか?実験医学2014

    • Author(s)
      竹内 隆、林 利憲
    • Journal Title

      実験医学

      Volume: 32 Pages: 29-35

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.2013

    • Author(s)
      Inagawa M, Nakajima K, Makino T, Ogawa S, Kojima M, Ito S, Ikenishi A, Hayashi T, Schwartz RJ, Nakamura K, Obayashi T, Tachibana M, Shinkai Y, Maeda K, Miyagawa-Tomita S, Takeuchi T
    • Journal Title

      Mech Dev.

      Volume: 130 Issue: 11-12 Pages: 519-31

    • DOI

      10.1016/j.mod.2013.07.002

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Molecular genetic system for regenerative studies using newts.2013

    • Author(s)
      Hayashi T, Yokotani N, Tane S, Matsumoto A, Myouga A, Okamoto M, Takeuchi T.
    • Journal Title

      Development, Growth & Differentiation

      Volume: 55 Issue: 2 Pages: 229-36

    • DOI

      10.1111/dgd.12019

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 発生過程から成体にかけての心筋細胞の増殖パターンはどのように作られ、どのような意義があるのか?2013

    • Author(s)
      竹内 隆、池西 愛子、岡山 仁美、岩本 典子
    • Journal Title

      実験医学

      Volume: 31 Pages: 205-211

    • Related Report
      2013 Final Research Report
  • [Journal Article] なぜ、哺乳類は心臓を再生できず、イモリはできるのか?2013

    • Author(s)
      竹内 隆、池西 愛子、岡山 仁美、岩本 典子
    • Journal Title

      実験医学

      Volume: 31 Pages: 205-211

    • Related Report
      2012 Research-status Report
  • [Journal Article] Cell cycle regulation in mouse heart during embryonic and postnatal stages.2012

    • Author(s)
      Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T.
    • Journal Title

      Development, Growth & Differentiation

      Volume: 54 Issue: 8 Pages: 731-8

    • DOI

      10.1111/j.1440-169x.2012.01373.x

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells2012

    • Author(s)
      Akiko Takahashi
    • Journal Title

      Molecular Cell

      Volume: 45 Issue: 1 Pages: 123-131

    • DOI

      10.1016/j.molcel.2011.10.018

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Notch prosensory effects in the Mammalian cochlea are partially mediated by Fgf202012

    • Author(s)
      Munnamalai, V., Hayashi, T.,Bermingham-McDonogh, O.
    • Journal Title

      J. Neurosci

      Volume: 12 Issue: 37 Pages: 12876-12884

    • DOI

      10.1523/jneurosci.2250-12.2012

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 心筋細胞の増殖制御と心臓再生2014

    • Author(s)
      竹内隆
    • Organizer
      シンポジウム 幹細胞の増殖・分化と再生創薬
    • Place of Presentation
      米子コンベンションセンター米子市
    • Year and Date
      2014-02-21
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Molecularmechanisms of cell proliferation in cardiomyocytes during cardiac development and regeneration2014

    • Author(s)
      Takeuchi, T., Tane, S., Okayama,Ikenishi, A., H., Matsumoto, A.,Myouga, A., Hayashi, T.
    • Organizer
      CDB Symposium 2014
    • Place of Presentation
      RIKEN CDB 神戸市
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Molecular genetic system for regenerative studies using newts Iberian Ribbed Newts (Pleurodeles waltl)2014

    • Author(s)
      Hayashi, T., Yokotani, N., Matsumoto,A., Myouga, A., Sakamoto, K., Inoue,T., Kawaguchi, E., Agata, K., Sakuma,T., Yamamoto, T., Takeuchi, T.
    • Organizer
      CDB Symposium 2014
    • Place of Presentation
      RIKEN CDB、神戸市
    • Related Report
      2013 Final Research Report
  • [Presentation] Linage tracing analysis of cardiomyocytes in the newt cardiac regeneration by tamoxifen-inducible Cre-loxP system2014

    • Author(s)
      Myouga, A., Yokotani, N., Takeuchi, T.,Hayashi, T.
    • Organizer
      CDB Symposium 2014
    • Place of Presentation
      RIKENCDB、神戸市
    • Related Report
      2013 Final Research Report
  • [Presentation] イモリの心臓再生における心筋細胞の増殖と、再生心筋組織に対する寄与2014

    • Author(s)
      林 利憲、茗荷あゆみ、横谷 直樹、竹内隆
    • Organizer
      日本再生医療学会
    • Place of Presentation
      国立京都国際会館 京都市
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular mechanisms of cell proliferation in cardiomyocytes during cardiac development and regeneration.2014

    • Author(s)
      Takeuchi, T., Tane, S., Okayama, Ikenishi, A., H., Matsumoto, A., Myouga, A., Hayashi, T.
    • Organizer
      CDB Symposium 2014
    • Place of Presentation
      RIKEN CDB 神戸市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Molecular genetic system for regenerative studies using newts Iberian Ribbed Newts (Pleurodeles waltl).2014

    • Author(s)
      Hayashi, T., Yokotani, N., Matsumoto, A., Myouga, A., Sakamoto, K., Inoue, T., Kawaguchi, E., Agata, K., Sakuma, T., Yamamoto, T., Takeuchi, T.
    • Organizer
      CDB Symposium 2014
    • Place of Presentation
      RIKEN CDB 神戸市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Linage tracing analysis of cardiomyocytes in the newt cardiac regeneration by tamoxifen-inducible Cre-loxP system.2014

    • Author(s)
      Myouga, A., Yokotani, N., Takeuchi, T., Hayashi, T.
    • Organizer
      CDB Symposium 2014
    • Place of Presentation
      RIKEN CDB 神戸市
    • Related Report
      2013 Annual Research Report
  • [Presentation] イモリの心臓再生における心筋細胞の増殖と、再生心筋組織に対する寄与2014

    • Author(s)
      林利憲、茗荷 あゆみ、横谷 直樹、竹内 隆
    • Organizer
      日本再生医療学会
    • Place of Presentation
      国立京都国際会館 京都市
    • Related Report
      2013 Annual Research Report
  • [Presentation] 心筋細胞の増殖制御と心臓再生2014

    • Author(s)
      竹内隆
    • Organizer
      シンポジウム 幹細胞の増殖・分化と再生創薬
    • Place of Presentation
      米子コンベンションセンター 米子市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 心筋細胞の増殖制御と心臓再生2013

    • Author(s)
      竹内 隆
    • Organizer
      西日本心臓血管発生研究会
    • Place of Presentation
      広島大学、広島市
    • Year and Date
      2013-10-26
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] イモリの心臓再生過程における細胞系譜の追跡と再生心筋に対する寄与の解明2013

    • Author(s)
      茗荷 あゆみ,横谷 直樹,竹内 隆,林利憲
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸国際会議場神戸市
    • Related Report
      2013 Final Research Report
  • [Presentation] マウス心筋細胞のM 期阻害機構はいつ獲得されるのか?2013

    • Author(s)
      岡山 仁美,田根 将志,池西 愛子,竹内 隆
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸国際会議場 神戸市
    • Related Report
      2013 Final Research Report
  • [Presentation] 哺乳類心筋細胞のM 期進行阻害機構は心傷害によって解除されるか?2013

    • Author(s)
      池西 愛子,田根 将志,岡山 仁美,竹内 隆
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸国際会議場 神戸市
    • Related Report
      2013 Final Research Report
  • [Presentation] TALEN によるイモリのゲノム編集の可能性と、再生研究への展開2013

    • Author(s)
      林 利憲、坂本興亮、佐久間哲史、横谷直樹、井上武、川口恵里、阿形清和、山本卓、 竹内隆
    • Organizer
      ゲノム編集研究会
    • Place of Presentation
      広島大学、東広島市
    • Related Report
      2013 Final Research Report
  • [Presentation] 遺伝子操作、ゲノム編集技術を用いたイモリ再生研究の展開2013

    • Author(s)
      林 利憲、茗荷 あゆみ、 横谷 直樹、佐久間 哲史、 山本 卓、 竹内 隆
    • Organizer
      日本動物学会招待講演
    • Place of Presentation
      岡山大学 岡山市
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecularmechanisms of cell proliferation in cardiomyocytes during cardiacdevelopment and regeneration2013

    • Author(s)
      Takeuchi, T., Tane, S., Okayama,Ikenishi, A., Yokotani, N., Matsumoto,A., Myouga, A., Hayashi, T.
    • Organizer
      日本発生生物学会
    • Place of Presentation
      くにびきメッセ 松江市
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Linage tracing analysis ofcardiomyocytes in the newt cardiac regeneration by tamoxifen-inducible Cre-loxP system2013

    • Author(s)
      Myouga, A., Yokotani, N., Takeuchi, T.,Hayashi, T.
    • Organizer
      日本発生生物学会
    • Place of Presentation
      くにびきメッセ 松江市
    • Related Report
      2013 Final Research Report
  • [Presentation] What molecule triggersre-proliferation of cardiomyocytes during newt heart regeneration?2013

    • Author(s)
      Yokotani, N., Inoue, T., Kawaguchi, E.,Agata, K., Takeuchi, T., Hayashi, T.
    • Organizer
      日本発生生物学会
    • Place of Presentation
      くにびきメッセ 松江市
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular genetic systemfor regenerative studies using newt2013

    • Author(s)
      Hayashi, T., Yokotani, N., Matsumoto,A., Myouga, A., Okamoto, M.,Takeuchi, T.
    • Organizer
      日本発生生物学会
    • Place of Presentation
      くにびきメッセ 松江市
    • Related Report
      2013 Final Research Report
  • [Presentation] なぜ、哺乳類は心臓を再生できず、イモリはできるのか?2013

    • Author(s)
      竹内隆、田根将志、横谷直樹、岡山仁美、池西愛子、松本晃、茗荷あゆみ、林利憲
    • Organizer
      日本再生医療学会
    • Place of Presentation
      パシフィコ横浜 横浜市
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] 両生類のイモリを用いた心臓再生機構の解明2013

    • Author(s)
      林利憲、横谷直樹、松本晃、茗荷あゆみ、川口恵理、井上武、阿形清和、竹内隆
    • Organizer
      日本再生医療学会
    • Place of Presentation
      パシフィコ横浜 横浜市
    • Related Report
      2013 Final Research Report
  • [Presentation] イモリの心臓再生過程における細胞系譜の追跡と再生心筋に対する寄与の解明2013

    • Author(s)
      茗荷あゆみ,横谷直樹,竹内隆,林利憲
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸国際会議場 神戸市
    • Related Report
      2013 Annual Research Report
  • [Presentation] マウス心筋細胞のM 期阻害機構はいつ獲得されるのか?2013

    • Author(s)
      岡山仁美,田根将志,池西愛子,竹内隆
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸国際会議場 神戸市
    • Related Report
      2013 Annual Research Report
  • [Presentation] 哺乳類心筋細胞のM 期進行阻害機構は心傷害によって解除されるか?2013

    • Author(s)
      池西愛子,田根将志,岡山仁美,竹内隆
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸国際会議場 神戸市
    • Related Report
      2013 Annual Research Report
  • [Presentation] 心筋細胞の増殖制御と心臓再生2013

    • Author(s)
      竹内隆
    • Organizer
      西日本心臓血管発生研究会
    • Place of Presentation
      広島大学 広島市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] TALENによるイモリのゲノム編集の可能性と、再生研究への展開2013

    • Author(s)
      林利憲、坂本興亮、佐久間哲史、横谷直樹、井上武、川口恵里、阿形清和、山本卓、 竹内隆
    • Organizer
      ゲノム編集研究会
    • Place of Presentation
      広島大学 東広島市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ゲノム編集技術を用いたイモリ再生研究の展開2013

    • Author(s)
      林利憲、茗荷あゆみ、 横谷直樹、 佐久間哲史、 山本卓、 竹内隆 遺伝子操作
    • Organizer
      日本動物学会
    • Place of Presentation
      岡山大学 岡山市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Molecular mechanisms of cell proliferation in cardiomyocytes during cardiac development and regeneration.2013

    • Author(s)
      Takeuchi, T., Tane, S., Okayama, Ikenishi, A., Yokotani, N., Matsumoto, A., Myouga, A., Hayashi, T.
    • Organizer
      日本発生生物学会
    • Place of Presentation
      くにびきメッセ 松江市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Myouga, A., Yokotani, N., Takeuchi, T., Hayashi, T. Linage tracing analysis of cardiomyocytes in the newt cardiac regeneration by tamoxifen-inducible Cre-loxP system.2013

    • Author(s)
      Myouga, A., Yokotani, N., Takeuchi, T., Hayashi, T.
    • Organizer
      日本発生生物学会
    • Place of Presentation
      くにびきメッセ 松江市
    • Related Report
      2013 Annual Research Report
  • [Presentation] What molecule triggers re-proliferation of cardiomyocytes during newt heart regeneration?2013

    • Author(s)
      Yokotani, N., Inoue, T., Kawaguchi, E., Agata, K., Takeuchi, T., Hayashi, T.
    • Organizer
      日本発生生物学会
    • Place of Presentation
      くにびきメッセ 松江市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Molecular genetic system for regenerative studies using newt.2013

    • Author(s)
      Hayashi, T., Yokotani, N., Matsumoto, A., Myouga, A., Okamoto, M., Takeuchi, T.
    • Organizer
      日本発生生物学会
    • Place of Presentation
      くにびきメッセ 松江市
    • Related Report
      2013 Annual Research Report
  • [Presentation] なぜ、哺乳類は心臓を再生できず、イモリはできるのか?2013

    • Author(s)
      竹内 隆その他
    • Organizer
      日本再生医療学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 両生類のイモリを用いた心臓再生機構の解明2013

    • Author(s)
      林 利憲その他
    • Organizer
      日本再生医療学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 心筋細胞の増殖制御機構と心臓再生 : なぜ、イモリは心臓再生が可能で哺乳類は不可能なのか?2012

    • Author(s)
      竹内隆
    • Organizer
      分子病理学研究会
    • Place of Presentation
      恵那峡グランドホテル 恵那市
    • Year and Date
      2012-07-22
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular mechanisms of cell cycle arrest in cardiomyocytes during cardiac development and regeneration2012

    • Author(s)
      Takeuchi, T., Tane, S., Ikenishi, A.,Okayama, H., Yokotani, N.,Matsumoto, A., Hayashi, T.
    • Organizer
      日本分子生物学会 指定演者
    • Place of Presentation
      福岡国際会議場 福岡市
    • Related Report
      2013 Final Research Report
  • [Presentation] How doadult mammalian cardiomyocytesmaintain the proliferation arrest?2012

    • Author(s)
      Tane, S., Yoshitome, Satoh, Y.,Iwamoto, N., Okayama, H., Ikenishi,A., Hayashi, T., Takeuchi, T.
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場 福岡市
    • Related Report
      2013 Final Research Report
  • [Presentation] How does cell cycle ofmouse cardiomyocytes arrest? : analysis of cell cycle regulator2012

    • Author(s)
      Ikenishi, Iwamoto, N., Tane, S.,Okayama, H., Satoh, Y., Hayashi, T.,Takeuchi, T.
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場 福岡市
    • Related Report
      2013 Final Research Report
  • [Presentation] How does cell cycle of mouse cardiomyocytes arrest? : analysis of cell cycle pattern2012

    • Author(s)
      Okayama, H., Tane, S., Iwamoto, N.,Ikenishi, A., Satoh, Y., Hayashi, T.,Takeuchi, T.
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場 福岡市
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular geneticsystem for regenerative studiesusing newt2012

    • Author(s)
      Hayashi, T., Yokotani, N., Tane, S.,Matsumoto, A., Myouga, A.,Takeuchi, T.
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場福岡市
    • Related Report
      2013 Final Research Report
  • [Presentation] What molecule triggers reproliferationof cardiomyocytesduring newt heart regeneration?2012

    • Author(s)
      Yokotani, N., Matsumoto, A.,Hayashi, T., Inoue, T., Shibata, N.,Kawaguchi, E., Agata, K., Takeuchi,T.
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場 福岡市
    • Related Report
      2013 Final Research Report
  • [Presentation] 心筋細胞の増殖制御機構と心臓再生 : マウスとイモリとを比較する2012

    • Author(s)
      竹内隆、田根将志、岡山仁美、池西愛子、岩本典子、横谷直樹、松本晃、林利憲
    • Organizer
      日本動物学会
    • Place of Presentation
      大阪大学 豊中市
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] イモリ心臓再生における心筋細胞増殖の時空間パターンの解明2012

    • Author(s)
      林利憲、松本晃、横谷直樹、川口恵理、西村 理、井上武、阿形清和、竹内隆
    • Organizer
      日本動物学会
    • Place of Presentation
      大阪大学豊中市
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Howdo adult mammalian cardiomyocytesmaintain the proliferation arrest?2012

    • Author(s)
      Tane, S., Yoshitome, Satoh, Y.,Iwamoto, N., Okayama, H., Ikenishi,A., Hayashi, T., Takeuchi, T.
    • Organizer
      日本発生生物学会、細胞生物学会合同大会
    • Place of Presentation
      神戸国際会議場 神戸市
    • Related Report
      2013 Final Research Report
  • [Presentation] Development of the model system formolecular genetics for theregene-rative studies in urodeles2012

    • Author(s)
      Hayashi, T., Yokotani, N., Matsumoto,A., Tane, S., Takeuchi, T.
    • Organizer
      日本発生生物学会、細胞生物学会合同大会
    • Place of Presentation
      神戸国際会議場 神戸市
    • Related Report
      2013 Final Research Report
  • [Presentation] Analysis ofthe expression patterns of Cell cycleregulator genes during newt cardiac egeneration2012

    • Author(s)
      Matsumoto, A., Hayashi, T., Yokotani,N., Kawaguchi, E., Nishimura, O.,Agata, K., Takeuchi, T.
    • Organizer
      日本発生生物学会、細胞生物学会合同大会
    • Place of Presentation
      神戸国際会議場 神戸市
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular mechanisms of cell cycle arrest in cardiomyocytes during cardiac development and regeneration2012

    • Author(s)
      Takeuchi et al
    • Organizer
      日本分子生物学会(指定演者)
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Related Report
      2012 Research-status Report
  • [Presentation] How do adult mammalian cardiomyocytes maintain the proliferation arrest?2012

    • Author(s)
      Tane et al
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Related Report
      2012 Research-status Report
  • [Presentation] How does cell cycle of mouse cardiomyocytes arrest? :analysis of cell cycle regulators.2012

    • Author(s)
      Ikenishi et al
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Related Report
      2012 Research-status Report
  • [Presentation] How does cell cycle of mouse cardiomyocytes arrest? : analysis of cell cycle pattern.2012

    • Author(s)
      Okayama et al
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Molecular genetic system for regenerative studies using newts.2012

    • Author(s)
      Hayashi et al
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Related Report
      2012 Research-status Report
  • [Presentation] hat molecule triggers re-proliferation of cardiomyocytes during newt heart regeneration.2012

    • Author(s)
      Yokotani et al
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 心筋細胞の増殖制御機構と心臓再生:マウスとイモリとを比較する2012

    • Author(s)
      竹内 隆その他
    • Organizer
      日本動物学会
    • Place of Presentation
      大阪大学(豊中市)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] イモリ心臓再生における心筋細胞増殖の時空間パターンの解明2012

    • Author(s)
      林 利憲その他
    • Organizer
      日本動物学会
    • Place of Presentation
      大阪大学(豊中市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 心筋細胞の増殖制御機構と心臓再生:なぜ、イモリは心臓再生が可能で哺乳類は不可能なのか?2012

    • Author(s)
      竹内 隆
    • Organizer
      分子病理学研究会 特別講演
    • Place of Presentation
      恵那峡グランドホテル(恵那市)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] How do adult mammalian cardiomyocytes maintain the proliferation arrest?2012

    • Author(s)
      Tane et al
    • Organizer
      日本発生生物学会、細胞生物学会合同大会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Development of the model system for molecular genetics for the regenerative studies in urodeles.2012

    • Author(s)
      Hayashi et al
    • Organizer
      日本発生生物学会、細胞生物学会合同大会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Analysis of the expression patterns of Cell cycle regulator genes during newt cardiac regeneration.2012

    • Author(s)
      Matsumoto et al
    • Organizer
      日本発生生物学会、細胞生物学会合同大会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Related Report
      2012 Research-status Report
  • [Book] 両生類におけるTALEN を用いた遺伝子改変 実験医学別册 今すぐ始めるゲノム編集2014

    • Author(s)
      林 利憲、坂根 祐人、竹内 隆、鈴木 賢一(山本卓編集)
    • Publisher
      羊土社
    • Related Report
      2013 Final Research Report
  • [Remarks]

    • URL

      http://toridaimedseitai.web.fc2.com/index.html

    • Related Report
      2013 Final Research Report
  • [Remarks]

    • URL

      http://www.med.tottori-u.ac.jp/biosign/5982.html

    • Related Report
      2013 Final Research Report
  • [Remarks] 鳥取大学 医学部 生命科学科 生体情報学分野

    • URL

      http://toridaimedseitai.web.fc2.com/index.html

    • Related Report
      2013 Annual Research Report
  • [Remarks] 生体情報学分野

    • URL

      http://www.med.tottori-u.ac.jp/biosign/5982.html

    • Related Report
      2013 Annual Research Report
  • [Remarks] 鳥取大学医学部生命科学科生体情報学分野

    • URL

      http://toridaimedseitai.web.fc2.com/index.html

    • Related Report
      2012 Research-status Report
  • [Remarks] 生体情報学分野

    • URL

      http://www.med.tottori-u.ac.jp/biosign/5982.html

    • Related Report
      2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi