Diversity and evolution of gene expression in reptilian mitochondria
| Project/Area Number |
24657163
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Evolutionary biology
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| Research Institution | Nagoya City University |
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Principal Investigator |
KUMAZAWA Yoshinori 名古屋市立大学, 大学院システム自然科学研究科, 教授 (60221941)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | ミトコンドリア / RNA-Seq / 爬虫類 / 次世代シーケンス / RNA編集 / polyA付加 / RNA / 遺伝子発現 / polyA / 次世代シーケンサー / トランスクリプトーム / ミトコンドリアDNA / 翻訳異常 / 遺伝子配置変動 |
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| Research Abstract |
We conducted RNA-Seq experiments using animal species representing Reptilia. We found some variations in the distribution of polyA-addition sites to mRNAs and some of them are consistent with variations of gene arrangements of mtDNAs. Accuracy of polyA addition was lowered to some extent for particular mRNAs in a species though reasons for this are currently unknown. Relative ratio of each mRNA abundance in a species is changed in a way that is consistent with an idea that polycistronic mRNAs are created from one control region to another. The gene expression system in mitochondria has variations and is evolving in Reptilia.
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Report
(3 results)
Research Products
(22 results)
