Study on surface-recognition signaling which induce surface adhesion in filamentous fungi
| Project/Area Number |
24658087
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied microbiology
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| Research Institution | National Institute of Agrobiological Sciences |
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Principal Investigator |
NISHIMURA Marie 独立行政法人農業生物資源研究所, 植物科学領域 植物・微生物間相互作用研究ユニット, 主任研究員 (30370670)
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| Co-Investigator(Kenkyū-buntansha) |
中野 美紀 独立行政法人産業技術総合研究所, 先進製造プロセス研究部門, 研究員 (20415722)
三宅 晃司 独立行政法人産業技術総合研究所, 先進製造プロセス研究部門, グループ長 (30302392)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | バイオフィルム / 糸状菌 / シグナル伝達 / 接着 / ヘテロ3量体Gタンパク質 / バイオフォルム |
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| Research Abstract |
Controlling of fungal biofilms has been an important issue to supply clean environments for industrial, medical and living purposes. Biofilm formation in Ascomycete filamentous fungi starts with the fungal adhering to substrate surfaces. This surface adhesion apperes to be induced by fungal recognition of the surface physiological cues. In this project, we studied mechanisms that triggered adhesion in the Ascomycete fungi, Magnaporthe oryzae. Our results suggested that recognition signaling of certain surface cues negatively regulated the fungal adhesion. We also identified a conserved cell wall protein which was involved in the surface adhesion. Our study will contribute to the further understanding of fungal adhesion mechanisms and the development of anti-biofilm technologies.
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Report
(3 results)
Research Products
(5 results)
