Identification of transcription regulatory factor using chromatinized DNA template immobilized on microbeads
Project/Area Number |
24659121
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Single-year Grants |
Research Field |
General medical chemistry
|
Research Institution | Hokkaido University |
Principal Investigator |
|
Project Period (FY) |
2012-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 転写因子 / 転写制御因子 / HNF4 alpha / ES細胞 / HNF4alpha |
Research Abstract |
Many evidence including that all of the Yamanaka factors necessary for generation of IPS cells are transcription factors indicates that transcription factors play an very important role in regulation of gene expression. To address the mechanism how transcription factor regulates gene transcription, we performed the identification of transcription regulatory factor using chromatinized DNA template.
|
Report
(3 results)
Research Products
(20 results)
-
-
-
[Journal Article] Identification of anti-Sez6l2 antibody in a patient with cerebellar ataxia and retinopathy2013
Author(s)
Yaguchi H, Yabe I, Takahashi H, Okumura F, Takeuchi A, Horiuchi, K, Kan T, Kanda, A, Saito W, Matsumoto M, Nakayama KI, Hatakeyama S and Sasaki H
-
Journal Title
J. Neurol.
Volume: 261
Issue: 1
Pages: 224-226
DOI
Related Report
Peer Reviewed
-
[Journal Article] Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation.2012
Author(s)
Yasukawa T, Bhatt S, Takeuchi T, Kawauchi J, Takahashi H, Tsutsui A, Muraoka T, Inoue M, Tsuda M, Kitajima S, Conaway RC, Conaway JW, Trainor PA, Aso T.
-
Journal Title
Cell Rep
Volume: 2(5)
Issue: 5
Pages: 1129-36
DOI
Related Report
Peer Reviewed
-
[Journal Article] TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and indices neuritogenesis2012
Author(s)
Yaguchi, H., Okumura, F., Takahashi, H., Kano, T., Kameda, H., Uchigashima, M., Tanaka, S., Watanabe, M., Sasaki, H. and Hatakeyama, S.
-
Journal Title
J. Biol. Chem.
Volume: 287
Issue: 15
Pages: 12050-12059
DOI
Related Report
Peer Reviewed
-
-
[Presentation] Med26はLittle elongation complexをリクルートすることでsmall nuclear RNA遺伝子の発現を制御する2013
Author(s)
高橋秀尚,瀧川一学, Delnur Anwar,柴田美音,佐藤チエリ,佐藤滋生, Ranjan Amol, Chris W. Seidel,築山忠維,渡部昌,林正康,大川恭行, Joan W. Conaway, Ronald C. Conaway,畠山鎮次
Organizer
第36回日本分子生物学会
Place of Presentation
神戸ポートピアホテル(神戸)
Related Report
-
-
[Presentation] Med26はLittle elongation complexをリクルートすることでsmall nuclear RNA遺伝子の発現を制御する2013
Author(s)
高橋秀尚, 瀧川一学, Delnur Anwar, 柴田美音, 佐藤チエリ, 佐藤滋生, Ranjan Amol, Chris W. Seidel, 築山忠維, 渡部昌, 林正康, 大川恭行, Joan W. Conaway, Ronald C. Conaway, 畠山鎮次
Organizer
第36回日本分子生物学会年会
Place of Presentation
神戸ポートピアアイランド(神戸市)
Related Report
-
-
-
-
-
[Presentation] Med26はLittle elongation complexをリクルートすることでsmall nuclear RNA遺伝子の発現を制御する2012
Author(s)
高橋秀尚,佐藤智信,Conaway, J.W., Conaway, R.C.,畠山鎮次 高橋秀尚,佐藤智信,Conaway, J.W., Conaway, R.C.,畠山鎮次
Organizer
第35回日本分子生物学会年会
Place of Presentation
福岡国際会議場、マリンメッセ福岡(福岡)
Related Report
-
-
-
-
-
-