Identification of phosphatidylglycerophosphate-binding proteins.
| Project/Area Number |
24659124
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
General medical chemistry
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| Research Institution | Akita University |
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Principal Investigator |
TAKASUGA SHUNSUKE 秋田大学, 医学(系)研究科(研究院), 助教 (90375262)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 細胞内シグナル伝達 / リン脂質 / ミトコンドリア |
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| Research Abstract |
Phosphatidylglycerophosphate (PGP) is a mitochondrial glycerophospholipid, known as a precursor of cardiolipin. We tried to identify PGP-binding proteins in mitochondria for elucidation of unique physiological functions of PGP. However, none of mitochondrial proteins containing known phospholipid binding domains binds PGP. Therefore, PGP-binding proteins might have a novel lipid-binding domain.
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Report
(3 results)
Research Products
(7 results)
