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nalysis of non-coding RNAs transcribed from ultraconserved regions in digestive tract cancer and its diagnostic and therapeutic application

Research Project

Project/Area Number 24659163
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Human pathology
Research InstitutionHiroshima University

Principal Investigator

YASUI Wataru  広島大学, 医歯薬保健学研究院(医), 教授 (40191118)

Co-Investigator(Renkei-kenkyūsha) OUE Naohide  広島大学, 大学院医歯薬保健学研究院, 准教授 (60346484)
Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
KeywordsncRNA / 超保存領域(T-UCR) / 消化管癌 / 診断・治療展開 / 発現制御 / メチル化 / 非翻訳RNA / 超保存領域(T-UCR)
Research Abstract

Transcribed ultraconserved region (T-UCR) transcripts are a novel class of long non-coding RNAs transcribed from ultraconserved regions (UCRs). The expression analysis of T-UCR in digestive tract cancers demonstrated that, in gastric cancer, most of T-UCRs including UCR118+A and 158+A were down-regulated by methylation, whereas UCR416+A and 420+A were overexpressed. Down-regulation of miR-148 and miR-143/-145 participated in cancer invasion and morphogenesis with interaction with stromal cells and served as prognostic factor of gastric cancer patients.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (64 results)

All 2014 2013 2012 2011 Other

All Journal Article (29 results) (of which Peer Reviewed: 13 results,  Open Access: 1 results) Presentation (32 results) (of which Invited: 10 results) Book (2 results) Remarks (1 results)

  • [Journal Article] High miR-21 expression from FFPE tissues is associated with poor survival and response to adjuvant chemotherapy in colon cancer2014

    • Author(s)
      Oue N, Anami K, Schetter AJ, Moehler M, Okayama H, Khan MA, Bowman ED, Mueller A, Schad A, Shimomura M, Hinoi T, Aoyagi K, Sasaki H, Okajima M, Ohdan H, Galle PR, Yasui W and Harris CC
    • Journal Title

      Int J Cancer

      Volume: 134 Pages: 1926-1934

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] MicroRNA-143 regulates collagen type III expression in stromal fibroblasts of scirrhous type gastric cancer2014

    • Author(s)
      Naito Y, Sakamoto N, Oue N, Yashiro M, Sentani K, Yanagihara K, Hirakawa K and Yasui W
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 228-235

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] MiR-148a is down-regulated in gastric cancer, targets MMP7 and indicates tumor invasiveness and poor prognosis2014

    • Author(s)
      Sakamoto N, Naito Y, Oue N, Sentani K, Uraoka N, Oo HZ, Yanagihara K, Aoyagi K, Sasaki H and Yasui W
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 236-243

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] NRD1, which encodes nardilysin protein, promotes esophageal cancer cell invasion through induction of MMP2 and MMP3 expression2014

    • Author(s)
      Uraoka N, Oue N, Sakamoto N, Sentani K, Oo HZ, Naito Y, Noguchi T and Yasui W
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 134-140

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] Identification of novel transmembrane proteins in scirrhous type gastric cancer by Escherichia coli ampicillin trap (CAST) method : TM9SF3 participates in tumor invasion and serves as a prognostic factor2014

    • Author(s)
      Oo HZ, Sentani K, Sakamoto N, Anami K, Naito Y, Oshima T, Yanagihara K, Oue N and Yasui W
    • Journal Title

      Pathobiology

      Volume: 81 Pages: 138-148

    • Related Report
      2013 Final Research Report
  • [Journal Article] Clinicopathological significance of MMP-7, lamininγ2 and EGFR at the invasive front of gastric carcinoma2014

    • Author(s)
      Sentani K
    • Journal Title

      Gastric Cancer

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Combining molecular targeted drugs to inhibit both cancer cells and activated stromal cells in gastric cancer2013

    • Author(s)
      Onoyama M, Kitadai Y, Tanaka Y, Yuge R, Shinagawa K, Tanaka S, Yasui W and Chayama K
    • Journal Title

      Neoplasia

      Volume: 15 Pages: 1391-1399

    • Related Report
      2013 Final Research Report
  • [Journal Article] Improved PCR amplification for molecular analysis using DNA from long-term preserved formalin-fixed, paraffin-embedded lung cancer tissue specimens2013

    • Author(s)
      Taga M, Eguchi H, Shinohara T, Takahashi K, Ito R, Yasui W, Nakachi K, Kusunoki Y and Hamatani K
    • Journal Title

      Int J Clin Exp Pathol

      Volume: 6 Pages: 76-79

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells2013

    • Author(s)
      Mori R, Yoshida K, Tanahashi T, Yawata K, Kato J, Okumura N, Tsutani Y, Okada M, Oue N and Yasui W
    • Journal Title

      Gastric Cancer

      Volume: 16 Pages: 345-354

    • Related Report
      2013 Final Research Report
  • [Journal Article] Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer2013

    • Author(s)
      Shinagawa K, Kitadai Y, Tanaka M, Sumida T, Onoyama M, Ohnishi M, Ohara E, Higashi Y, Tanaka S, Yasui W and Chayama K
    • Journal Title

      Int J Cancer

      Volume: 132 Pages: 813-823

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] Expression of miR-486 is a potential prognostic factor after nephrectomy in advanced renal cell carcinoma2013

    • Author(s)
      Goto K
    • Journal Title

      Mol Clin Oncol

      Volume: 1 Pages: 235-240

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells.2013

    • Author(s)
      Mori R
    • Journal Title

      Gastric Cancer

      Volume: 16 Issue: 3 Pages: 345-354

    • DOI

      10.1007/s10120-012-0191-0

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of olfactomedin 4 and claudin-18 in serrated neoplasia of the colorectum: a characteristic pattern is associated with sessile serrated lesion.2013

    • Author(s)
      Sentani K, Sakamoto N, Shimamoto F, Anami K, Oue N, Yasui W.
    • Journal Title

      Histopathology

      Volume: - Issue: 7 Pages: 1018-1027

    • DOI

      10.1111/his.12099

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Signal peptidase complex 18, encodes by SEC11A, contributes to progression via TGF-a secretion in gastric cancer2013

    • Author(s)
      Naohide Oue, Yutaka Naito, Tetsutaro Hayashi, Misato Takigahira, Akiko Kawano-Nagatsuma, Kazuhiro Sentani, Naoya Sakamoto, Htoo Zarni Oo, Naohiro Uraoka, Kazuyoshi Yanagihara, Atsushi Ochiai, Hiroki Sasaki, Wataru Yasui
    • Journal Title

      Oncogene

      Volume: 33 Issue: 30 Pages: 3918-3926

    • DOI

      10.1038/onc.2013.364

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Improved PCR amplification for molecular analysis using DNA from long-term preserved formalin-fixed, paraffin-embedded lung cancer tissue specimens2013

    • Author(s)
      Taga M
    • Journal Title

      International Journal of Clinical and Experimental Pathology

      Volume: 6 Pages: 76-79

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Expression of miR-486 is a potential prognostic factor after nephrectomy in advanced renal cell carcinoma2013

    • Author(s)
      Goto K
    • Journal Title

      Molecular and Clinical Oncology

      Volume: 1 Pages: 235-240

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells2013

    • Author(s)
      Mori R
    • Journal Title

      Gastric Cancer

      Volume: 印刷中

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Deficiency of claudin-18 causes paracellular H+ leakage, up-regulation of interleukin-1beta, and atrophic gastritis in mice2012

    • Author(s)
      Hayashi D, Tamura A, Tanaka H, Yamazaki Y, Watanabe S, Suzuki K, Suzuki K, Sentani K, Yasui W, Rakugi H, Isaka Y and Tsukita S
    • Journal Title

      Gastroenterology

      Volume: 142 Pages: 292-304

    • Related Report
      2013 Final Research Report
  • [Journal Article] Upregulation of HOXA10 in gastric cancer with the intestinal mucin phenotype : Reduction during tumor progression and favorable prognosis2012

    • Author(s)
      Sentani K, Oue N, Naito Y, Sakamoto N, Anami K, Oo HZ, Uraoka N, Aoyagi K, Sasaki H and Yasui W
    • Journal Title

      Carcinogenesis

      Volume: 33 Pages: 1081-1088

    • NAID

      120005308208

    • Related Report
      2013 Final Research Report
  • [Journal Article] Cytokeratin 7 is a predictive marker for survival in patients with esophageal squamous cell carcinoma2012

    • Author(s)
      Oue N, Noguchi T, Anami K, Kitano S, Sakamoto N, Sentani K, Uraoka N, Aoyagi K, Yoshida T, Sasaki H and Yasui W
    • Journal Title

      Ann Surg Oncol

      Volume: 19 Pages: 1902-1910

    • Related Report
      2013 Final Research Report
  • [Journal Article] Liver-intestine cadherin induction by epidermal growth factor receptor is associated with intestinal differentiation of gastric cancer2012

    • Author(s)
      Sakamoto N, Oue N, Sentani K, Anami K, Uraoka N, Oo HZ, Naito Y, Hinoi T, Ohdan H, Yanagihara K, Aoyagi K, Sasaki H and Yasui W
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 1744-1750

    • Related Report
      2013 Final Research Report
  • [Journal Article] Reg IV is a direct target of intestinal transcription factor CDX2 in gastric cancer2012

    • Author(s)
      Naito Y, Oue N, Hinoi T, Sakamoto N, Sentani K, Ohdan H, Yanagihara K, Sasaki H and Yasui W
    • Journal Title

      PLoS One

      Volume: 7(11)

    • Related Report
      2013 Final Research Report
  • [Journal Article] MicroRNA-155 is a predictive marker for survival in patients with clear cell renal cell carcinoma.2012

    • Author(s)
      Shinmei S, Sakamoto N, Goto K, Sentani K, Anami K, Hayashi T, Teishima J, Matsubara A, Oue N, Kitadai Y, Yasui W.
    • Journal Title

      Int J Urol

      Volume: - Issue: 5 Pages: 468-477

    • DOI

      10.1111/j.1442-2042.2012.03182.x

    • Related Report
      2013 Annual Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Upregulation of HOXA10 in gastric cancer with the intestinal mucin phenotype: reduction during tumor progression and favorable prognosis.2012

    • Author(s)
      Sentani K, Oue N, Naito Y, Sakamoto N, Anami K, Oo HZ, Uraoka N, Aoyagi K, Sasaki H, Yasui W.
    • Journal Title

      Carcinogenesis

      Volume: 33 Issue: 5 Pages: 1081-1088

    • DOI

      10.1093/carcin/bgs121

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Liver-intestine cadherin induction by epidermal growth factor receptor is associated with intestinal differentiation of gastric cancer2012

    • Author(s)
      Sakamoto N, Oue N, Sentani K, Anami K, Uraoka N, Naito Y, Oo HZ, Hinoi T, Ohdan H, Yanagihara K, Aoyagi K, Sasaki H, Yasui W.
    • Journal Title

      Liver-intestine cadherin induction by epidermal growth factor receptor is associated with intestinal differentiation of gastric cancer

      Volume: 103(9) Issue: 9 Pages: 1744-50

    • DOI

      10.1111/j.1349-7006.2012.02353.x

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancer.2012

    • Author(s)
      Naito Y, Oue N, Hinoi T, Sakamoto N, Sentani K, Ohdan H, Yanagihara K, Sasaki, H, Yasui W.
    • Journal Title

      PLoS One

      Volume: 7(11) Issue: 11 Pages: 47545-47545

    • DOI

      10.1371/journal.pone.0047545

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Cytokeratin 7 is a Predictive Marker for Survival in Patients with Esophageal Squamous Cell Carcinoma2011

    • Author(s)
      Naohide Oue, Tsuyoshi Noguchi, Wataru Yasui.(他8名, 2番目)
    • Journal Title

      Ann Surg Oncol.

      Volume: 19 Issue: 6 Pages: 1902-1910

    • DOI

      10.1245/s10434-011-2175-4

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Signal peptidase complex 18, encoded by SEC11A, contributes to progression via TGF-a secretion in gastric cancer

    • Author(s)
      Oue N, Naito Y, Hayashi T, Takigahira M, Kawano-Nagatsuma A, Sentani K, Sakamoto N, Oo HZ, Uraoka N, Yanagihara K, Ochiai A, Sasaki H and Yasui W
    • Journal Title

      Oncogene

      Volume: (In press)

    • Related Report
      2013 Final Research Report
  • [Journal Article] Clinicopathological significance of MMP-7, lamininγ2 and EGFR at the invasive front of gastric carcinoma

    • Author(s)
      Sentani K, Matsuda M, Oue N, Uraoka N, Naito Y, Sakamoto N and Yasui W
    • Journal Title

      Gastric Cancer

      Volume: (In press)

    • Related Report
      2013 Final Research Report
  • [Presentation] Novel biomarkers and therapeutic targets of gastric cancer2013

    • Author(s)
      Yasui W, Oue N, Anami K, Oo HZ and Sentani K
    • Organizer
      The 4th JCA-AACR Special Joint Conference : The Latest Advances in Gastric Cancer Research"From Basic Science to Therapeutics"
    • Place of Presentation
      Urayasu, Chiba (Japan)
    • Related Report
      2013 Final Research Report
  • [Presentation] miR-148a, down-regulated in gastric cancer, targets MMP7 and participates in tumor invasion and poor prognosis2013

    • Author(s)
      Sakamoto N, Naito Y, Oue N, Sentani K, Uraoka N, Oo HZ, Yanagihara K, Aoyagi K, Sasaki H and Yasui W
    • Organizer
      10^<th> International Gastric Cancer Congress
    • Place of Presentation
      Verona (Italy)
    • Related Report
      2013 Final Research Report
  • [Presentation] HP and carcinogenesis -Pathogenesis and novel diagnostic and therapeutic targets2013

    • Author(s)
      Yasui W
    • Organizer
      10^<th> International Gastric Cancer Congress, Symposium 2"HP and Carcinogenesis"
    • Place of Presentation
      Verona (Italy)
    • Related Report
      2013 Final Research Report
  • [Presentation] Novel Biomarkers and therapeutic targets of scirrhous type stomach cancer2013

    • Author(s)
      Yasui W
    • Organizer
      Commemorative Symposium for the 2nd anniversary of SNUCH (Seoul National University Cancer Hospital), Special Lecture
    • Place of Presentation
      Seoul (Korea)
    • Related Report
      2013 Final Research Report
  • [Presentation] スキルス胃癌形態形成におけるmiR-143の役割と腫瘍マーカーとしての有用性2013

    • Author(s)
      内藤寛,坂本直也,浦岡直礼,仙谷和弘,大上直秀,八代正和,平川弘聖,安井弥
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] microRNA-143のスキルス胃癌における機能と腫瘍マーカーとしての有用性2013

    • Author(s)
      内藤寛,坂本直也,安野恭平,浦岡直礼,仙谷和弘,大上直秀,安井弥
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] 胃癌の分子・遺伝子を標的とした診断2013

    • Author(s)
      安井弥
    • Organizer
      第85回日本胃癌学会総会
    • Place of Presentation
      大阪
    • Related Report
      2013 Final Research Report
  • [Presentation] スキルス胃癌の病態と臨床応用−bench to bedside− : スキルス胃癌の分子病理と治療標的2013

    • Author(s)
      安井弥,Htoo Zarni Oo,坂本直也,大上直秀
    • Organizer
      第85回日本胃癌学会総会
    • Place of Presentation
      大阪(シンポジウム2)
    • Related Report
      2013 Final Research Report
  • [Presentation] Function of microRNA-143 and its potential of prognostic factor in scirrhous type gastric cancer2013

    • Author(s)
      Naito Y
    • Organizer
      The 104th Annual Meeting of the American Association for Cancer Research
    • Place of Presentation
      Washington D.C. (USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Biomarker for gastric cancer2013

    • Author(s)
      Yasui W
    • Organizer
      Commemorative Symposium for the 2nd anniversary of SNUCH
    • Place of Presentation
      Seoul (Korea)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] HP and carcinogenesis -Pathogenesis and novel diagnostic and therapeutic target2013

    • Author(s)
      Yasui W
    • Organizer
      10th International Gastric Cancer Congress
    • Place of Presentation
      Verona (Italy)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] miR-148a, down-regulated in gastric cancer, targets MMP7 and participates in tumor invasion and poor prognosis2013

    • Author(s)
      Sakamoto N
    • Organizer
      10th International Gastric Cancer Congress
    • Place of Presentation
      Verona (Italy)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Novel biomarkers and therapeutic targets of gastric cancer2013

    • Author(s)
      Yasui W
    • Organizer
      The 4th JCA-AACR Special Joint Conference
    • Place of Presentation
      Urayasu, Chiba (Japan)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] スキルス胃癌の分子病理と治療標的2013

    • Author(s)
      安井 弥
    • Organizer
      第85回日本胃癌学会総会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 胃癌の分子・遺伝子を標的とした診断2013

    • Author(s)
      安井 弥
    • Organizer
      第85回日本胃癌学会総会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Alteration of microRNA expression in gastrointestinal cancer2012

    • Author(s)
      Oue N, Sakamoto N, Naito Y, Sentani K, Harris CC and Yasui W
    • Organizer
      The 22^<nd> Hiroshima Cancer Seminar and the 4^<th> Japanese Association for RNA interference Joint International Symposium"MicroRNAs in cancer"
    • Place of Presentation
      Hiroshima (Japan)
    • Year and Date
      2012-08-30
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular targets for diagnosis and therapeutics of gastric cancer - Present and future2012

    • Author(s)
      Yasui W
    • Organizer
      The 17^<th> Japan-Korea Cancer Research Workshop
    • Place of Presentation
      Busan (Korea)
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular pathology of gastric cancer–microRNA and novel diagnostic & therapeutic targets2012

    • Author(s)
      Yasui W
    • Organizer
      The 96^<th> Annual Meeting of the German Society of Pathology, English Session, Lecture
    • Place of Presentation
      Berlin (Germany)
    • Related Report
      2013 Final Research Report
  • [Presentation] スキルス胃癌におけるmicroRNA-143の機能の解析2012

    • Author(s)
      内藤寛,坂本直也,浦岡直礼,仙谷和弘,大上直秀,安井弥
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Related Report
      2013 Final Research Report
  • [Presentation] 胃癌で発現が低下しているmiR-148aはMMP7を標的とし,浸潤に関与する2012

    • Author(s)
      坂本直也,内藤寛,仙谷和弘,大上直秀,安井弥
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Related Report
      2013 Final Research Report
  • [Presentation] 胃癌研究のマイルストーンと今後の展望Milestone and future of gastric cancer research2012

    • Author(s)
      安井弥
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Related Report
      2013 Final Research Report
  • [Presentation] 消化管がんの新規診断・治療開発に向けた分子病理学的アプローチ2012

    • Author(s)
      安井弥
    • Organizer
      第21回日本がん転移学会学術集会・総会
    • Place of Presentation
      広島
    • Related Report
      2013 Final Research Report
  • [Presentation] 統括病理学の現状と展望 : 消化管がんの発生と制御・形態の理解における統括病理学2012

    • Author(s)
      安井弥,仙谷和弘,坂本直也,大上直秀
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular pathology of gastric cancer - microRNA and novel diagnostic & therapeutic targets2012

    • Author(s)
      Yasui W
    • Organizer
      The 96th Annual Meeting of the German Society of Pathology
    • Place of Presentation
      Berlin (Germany)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Alteration of microRNA expression in gastrointestinal cancer2012

    • Author(s)
      Oue N
    • Organizer
      The 22nd Hiroshima Cancer Seminar and the 4th Japanese Association for RNA interference Joint International Symposium
    • Place of Presentation
      Hiroshima (Japan)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Molecular targets for diagnosis and therapeutics of gastric cancer - Present and future2012

    • Author(s)
      Yasui W
    • Organizer
      17th Japan-Korea Cancer Research Workshop
    • Place of Presentation
      Busan (Korea)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 消化管がんの発生と制御・形態の理解における統括病理学2012

    • Author(s)
      安井 弥
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 胃癌研究のマイルストーンと今後の展望2012

    • Author(s)
      安井 弥
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ホテルロイトン札幌(札幌)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 進行腎細胞癌におけるmiR-486発現の予後予測因子としての意義2012

    • Author(s)
      後藤景介
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ホテルロイトン札幌(札幌)
    • Related Report
      2012 Research-status Report
  • [Presentation] 胃癌で発現が低下しているmiR-148aはMMP7を標的とし、浸潤に関与する2012

    • Author(s)
      坂本 直也
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ホテルロイトン札幌(札幌)
    • Related Report
      2012 Research-status Report
  • [Presentation] microRNA-155発現の腎細胞癌における予後予測因子としての意義2012

    • Author(s)
      神明俊輔
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ホテルロイトン札幌(札幌)
    • Related Report
      2012 Research-status Report
  • [Presentation] スキルス胃癌におけるmicroRNA-143の機能の解析2012

    • Author(s)
      内藤 寛
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡(福岡)
    • Related Report
      2012 Research-status Report
  • [Book] Chapter 29: Molecular diagnostics of esophageal and gastric cancers. In : Principle of molecular diagnostics and personalized cancer medicine, ed. By Dongfeng Tan and Henry Lynch2013

    • Author(s)
      Yasui W, Oue N, Sentani K and Tan DF
    • Publisher
      Lippincott Williams & Wilkins, Philadelphia
    • Related Report
      2013 Final Research Report
  • [Book] Principle of molecular diagnostics and personalized cancer medicine2013

    • Author(s)
      Yasui W
    • Total Pages
      968
    • Publisher
      Lippincott Williams & Wilkins
    • Related Report
      2012 Research-status Report
  • [Remarks]

    • URL

      http://home.hiroshima-u.ac.jp/byori1/

    • Related Report
      2013 Final Research Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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