Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Research Abstract |
In my previous study, I isolated chemical compounds which bound to nucleic acid. Some of them had strong therapeutic effect on inflammatory diseases in the mice model. From this and other results, I hypothesized that the compounds targeted the endogenous immunogenic nucleic acid-protein complex. In this study, I tried to identify them and successfully identified both immunogenic nucleic acid and protein. Further study may provide the new strategy for the therapy of inflammatory diseases.
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