| Project/Area Number |
24659209
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Virology
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| Research Institution | Nagasaki University |
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Principal Investigator |
YASUDA Jiro 長崎大学, 熱帯医学研究所, 教授 (10282518)
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| Co-Investigator(Renkei-kenkyūsha) |
KUROSAKI Yohei 長崎大学, 熱帯医学研究所, 助教 (40415443)
URATA Shuzo 長崎大学, 熱帯医学研究所, 助教 (20614449)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 診断・治療 / 創薬 / 抗ウイルス / ラッサウイルス |
|---|
| Research Abstract |
By in silico screening using super computer DEGIMA system, we selected 374 chemical compounds as antiviral candidates which inhibit ebolavirus assembly. Antiviral activities of these compounds are currently under investigation.
We also established the high-through put screening system to identify the chemical compounds which inhibit Lassa virus assembly.
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