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Willingness-to-pay in health economics: International comparison survey in east Asian countries.

Research Project

Project/Area Number 24659252
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Medical sociology
Research InstitutionRitsumeikan University

Principal Investigator

SHIMOZUMA Kojiro  立命館大学, 生命科学部, 教授 (00248254)

Co-Investigator(Kenkyū-buntansha) SHIROIWA Takeru  帝京大学, 医学部, 講師 (20583090)
Project Period (FY) 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2012: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords医療経済評価 / QALY / 支払意思額 / 仮想評価法 / 国際情報交換 / タイ / 韓国 / 東アジア
Research Abstract

To examine the relationship between severity of health status and monetary value of a QALY, we obtained willingness to pay (WTP) values for one additional QALY in eight patterns of health states. We randomly sampled approximately 2,100 respondents from an online panel. We randomly allocated respondents to two of 14 questionnaires, with 300 responses expected for each pattern. After respondents were asked whether they wanted to purchase the treatment, double-bounded dichotomous choice method was used to obtain WTP values. The results clearly show that the WTP per QALY is higher for worse health states than for better health states. The WTP per QALY ranged from JPY 1.5 million to 5 million. For respondents who wanted to purchase the treatment, WTP values were significantly correlated with household income. This survey shows that QALY doesn’t necessarily have the same monetary value. Given these results, the WTP per QALY depends on the severity of health states.

Report

(2 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (53 results)

All 2013 2012 Other

All Journal Article (27 results) (of which Peer Reviewed: 24 results) Presentation (21 results) Book (4 results) Remarks (1 results)

  • [Journal Article] Current status and future perspectives of patient-reported outcome research in clinical trials for patients with breast cancer in Japan.2013

    • Author(s)
      Ohsumi S, Shimozuma K
    • Journal Title

      Breast Cancer

      Volume: online publication Issue: 4 Pages: 296-301

    • DOI

      10.1007/s12282-012-0368-8

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of preservation of the intercostobrachial nerve during axillary dissection on sensory change and health-related quality of life two years after breast cancer surgery2013

    • Author(s)
      Taira N, Shimozuma K, Ohsumi S, KuroiK, Shiroiwa T, Watanabe T, Saito M
    • Journal Title

      Breast Cancer

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Anemia affects the quality of life of Japanese cancer patients2013

    • Author(s)
      Wasada I, Eguchi H, Kurita M, Kudo S, Shishida T, Mishima Y, Saito Y, Ushirozawa N, Seto T, Shimozuma K, Morita S, Saito M, Yokomizo Y, Ishizawa K, Ohashi Y, Eguchi K
    • Journal Title

      Tokai Exp Clin Med

      Volume: 38(1) Pages: 7-11

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Anemia affects the quality of life of Japanese cancer patients.2013

    • Author(s)
      Wasada I
    • Journal Title

      Tokai Exp Clin Med

      Volume: 38 Pages: 7-11

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Health-related quality of life, psychological distress, and adverse events in postmenopausal women with breast cancer who receive tamoxifen, exemestane, or anastrozole as adjuvant endocrine therapy: National Surgical Adjuvant Study of Breast Cancer 04 (N-SAS BC 04).2012

    • Author(s)
      Takei H
    • Journal Title

      Breast Cancer Res Treat

      Volume: 133 Issue: 1 Pages: 227-236

    • DOI

      10.1007/s10549-011-1943-y

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Taxane-induced peripheral neuropathy and health-related quality of life in postoperative breast cancer patients undergoing adjuvant chemotherapy: N-SAS BC 02, a randomized clinical trial.2012

    • Author(s)
      Shimozuma K
    • Journal Title

      Support Care Cancer

      Volume: 20 Issue: 12 Pages: 3355-3364

    • DOI

      10.1007/s00520-012-1492-x

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 世界で医療経済評価はどのように用いられているか?-7カ国の比較調査結果と日本での応用可能性についての検討2012

    • Author(s)
      福田敬、白岩健、五十嵐中、小林慎、池田俊也、能登真一、下妻晃二郎、坂巻弘之
    • Journal Title

      医薬経済研究

      Volume: 23 Pages: 147-164

    • NAID

      40019389667

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 特集/ISPOR日本部会共同企画医療経済評価に関する諸問題-理論的・倫理的側面からの検討2012

    • Author(s)
      下妻晃二郎
    • Journal Title

      薬剤疫学

      Volume: 17(1) Pages: 3-3

    • Related Report
      2012 Final Research Report
  • [Journal Article] 1.医療経済評価における費用の取り扱いに関する論点2012

    • Author(s)
      坂巻弘之、石田博、福田敬、白岩健、下妻晃二郎
    • Journal Title

      薬剤疫学

      Volume: 17(1) Pages: 14-20

    • NAID

      130003297454

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 2.医療経済評価における非関連費用の取扱い2012

    • Author(s)
      五十嵐中、橋本義彦、白岩健、小林慎、赤沢学、池田俊也、福田敬、下妻晃二郎
    • Journal Title

      薬剤疫学

      Volume: 17(1) Pages: 21-26

    • NAID

      130003297455

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 4.医療経済評価における割引率をどのよう に設定すべきか?2012

    • Author(s)
      白岩健、福田敬、池田俊也、下妻晃二郎
    • Journal Title

      薬剤疫学

      Volume: 17(1) Pages: 33-38

    • NAID

      130003297457

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 5.健康アウトカムの割引率とその実証的研究2012

    • Author(s)
      葛西美恵、白岩健、池田俊也、下妻晃二郎
    • Journal Title

      薬剤疫学

      Volume: 17(1) Pages: 39-46

    • NAID

      130003297458

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 6.医療資源配分とQALY に関する倫理的側面からの考察2012

    • Author(s)
      齋藤信也、児玉聡、白岩健、下妻晃二郎、能登真一、後藤玲子
    • Journal Title

      薬剤疫学

      Volume: 17(1) Pages: 47-53

    • NAID

      130003297459

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Subjective and objective assessment of edema during adjuvant chemotherapy for breast cancer using taxane-containing regimens in a randomized controlled trial: The National Surgical Adjuvant Study of Breast Cancer 02.2012

    • Author(s)
      Ohsumi S
    • Journal Title

      Oncology

      Volume: 82 Issue: 3 Pages: 131-138

    • DOI

      10.1159/000336480

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cost-Effectiveness of Adjuvant FOLFOX Therapy for StageIII Colon Cancer in Japan Based on the MOSAIC Trial2012

    • Author(s)
      Shiroiwa T, Takeuchi T, Fukuda T, Shimozuma K, Ohashi Y
    • Journal Title

      Value Health

      Volume: 15(2) Pages: 255-260

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 産業医に役立つ最新の研究報告‐がん等の勤労者の罹患率の高い疾病の治療と職業生活の両立支援に係る社会的効用とコストパフォーマンス測定について2012

    • Author(s)
      下妻晃二郎
    • Journal Title

      産業医学ジャーナル

      Volume: 35(3) Pages: 76-79

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Journal Article] 世界で医療経済評価はどのように用いられているか?-7カ国の比較調査結果と日本での応用可能性についての検討2012

    • Author(s)
      福田敬
    • Journal Title

      医薬経済研究

      Volume: 23 Pages: 147-164

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 特集/ISPOR日本部会共同企画 医療経済評価に関する諸問題-理論的・倫理的側面からの検討2012

    • Author(s)
      下妻晃二郎
    • Journal Title

      薬剤疫学

      Volume: 17 Pages: 3-3

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 1.医療経済評価における費用の取り扱いに関する論点2012

    • Author(s)
      坂巻弘之
    • Journal Title

      薬剤疫学

      Volume: 17 Pages: 14-20

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 2.医療経済評価における非関連費用の取扱い2012

    • Author(s)
      五十嵐中
    • Journal Title

      薬剤疫学

      Volume: 17 Pages: 21-26

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 3.生産性費用とQALY:二重計上(double counting)問題の実証的検討2012

    • Author(s)
      白岩健
    • Journal Title

      薬剤疫学

      Volume: 17 Pages: 27-32

    • NAID

      130003297456

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 4.医療経済評価における割引率をどのように設定すべきか?2012

    • Author(s)
      白岩健
    • Journal Title

      薬剤疫学

      Volume: 17 Pages: 33-38

    • NAID

      130003297457

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 5.健康アウトカムの割引率とその実証的研究2012

    • Author(s)
      葛西美恵
    • Journal Title

      薬剤疫学

      Volume: 17 Pages: 39-46

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 6.医療資源配分とQALYに関する倫理的側面からの考察2012

    • Author(s)
      齋藤信也
    • Journal Title

      薬剤疫学

      Volume: 17 Pages: 47-53

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Subjective and objective assessments of edema during adjuvant chemotherapy for breast cancer using taxane-containing regimens in a randomized controlled trial: National Surgical Adjuvant Study of Breast Cancer (N-SAS BC) 02.2012

    • Author(s)
      Ohsumi S
    • Journal Title

      Oncology

      Volume: 82 Pages: 131-138

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cost-Effectiveness of Adjuvant FOLFOX Therapy for StageIII Colon Cancer in Japan Based on the MOSAIC Trial.2012

    • Author(s)
      Shiroiwa T
    • Journal Title

      Value Health

      Volume: 15 Pages: 255-260

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of preservation of the intercostobrachial nerve during axillary dissection on sensory change and health-related quality of life two years after breast cancer surgery.2012

    • Author(s)
      Taira N
    • Journal Title

      Breast Cancer

      Volume: in press

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] Comparison of PROs between thecontinuation and stop groups after 5 years of anastrozole: NSAS-BC 052013

    • Author(s)
      Yagata H, Ohtsu H, Shimozuma K, Ohashi Y,Komoike Y, Saji S, Takei H, Nakamura T,Iwase T
    • Organizer
      13th St. Gallen International Breast Cancer Conference2013
    • Place of Presentation
      Gallen,Switzerland
    • Related Report
      2012 Final Research Report
  • [Presentation] Comparison of bone health in continuation and stop groups after 5 years of anastrozole: NSAS-BC 052013

    • Author(s)
      Takei H, Ohtsu H, Yagata H, Shimozuma K, Komoike Y, Saji S, Higaki K, Nakamura T, Ohashi Y, Iwase T
    • Organizer
      13th St. Gallen International Breast Cancer Conference
    • Place of Presentation
      Gallen,Switzerland
    • Related Report
      2012 Final Research Report
  • [Presentation] Comparison of PROs between the continuation and stop groups after 5 years of anastrozole: NSAS-BC 05.2013

    • Author(s)
      Yagata H
    • Organizer
      13th St. Gallen International Breast Cancer Conference
    • Place of Presentation
      St. Gallen, Switzerland
    • Related Report
      2012 Annual Research Report
  • [Presentation] Impact of preservation of the intercostobrachial nerve during axillary dissection on sensory change and health-related quality of life two years after breast cancer surgery2012

    • Author(s)
      Taira N, Shimozuma K, Ohsumi S, Kuroi K,Shiroiwa T, Watanabe T, Saito M
    • Organizer
      35th San Antonio Breast Cancer Symposium
    • Place of Presentation
      San Antonio, USA
    • Year and Date
      2012-12-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Efficacy, toxicity and quality of life in older patients with early-stage breast cancer treated with oral Tegafur-uracil or classical CMF (cyclophosphamide, methotrexate, and fluorouracil): an exploratory analysis of National Surgical Adjuvant Study for Breast Cancer (N-SAS BC)01 Trial2012

    • Author(s)
      Hara F, Watanabe T, Shimozuma K, Ohashi Y
    • Organizer
      35th San Antonio Breast CancerSymposium
    • Place of Presentation
      San Antonio, USA
    • Year and Date
      2012-12-05
    • Related Report
      2012 Final Research Report
  • [Presentation] Minimally important difference (MID) in scores on the European organization for research and treatment of cancer (EORTC) Quality of Life Questionnaire Core 15 for Palliative (QLQ-C15-PAL)2012

    • Author(s)
      Miyazaki K, Suzukamo Y, Shimozuma K, Ohsumi S, Saito M, Nakayama T
    • Organizer
      19th Annual Conference of the International Society for Quality of Life Research (ISOQOL)
    • Place of Presentation
      Budapest,Hungary
    • Year and Date
      2012-10-27
    • Related Report
      2012 Final Research Report
  • [Presentation] Assessment of effects of response shift in palliative care patients using the structural equation modeling approach2012

    • Author(s)
      Suzukamo Y, Miyazaki K, Shimozuma K, Nakayama T
    • Organizer
      19th Annual Conference of the International Society for Quality of Life Research (ISOQOL)
    • Place of Presentation
      Budapest, Hungary
    • Year and Date
      2012-10-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 日本における1QALYあたりの支払意思額調査2012

    • Author(s)
      白岩健
    • Organizer
      第50回日本医療・病院管理学会学術総会
    • Place of Presentation
      学術総合センター,東京都
    • Year and Date
      2012-10-18
    • Related Report
      2012 Final Research Report
  • [Presentation] The margin between acquisition costs and reimbursement prices of generic drugs (Yakkasa) in Japan2012

    • Author(s)
      Shibahara H, Shiroiwa T, Shimozuma K
    • Organizer
      ISPOR 5th Asia-Pacific Conference
    • Place of Presentation
      Taipei, ChinaRepublic
    • Year and Date
      2012-09-24
    • Related Report
      2012 Final Research Report
  • [Presentation] QALY and productivity loss: empirical evidence for "double counting"2012

    • Author(s)
      Shiroiwa T, Fukuda T, Shimozuma K, Ikeda S
    • Organizer
      ISPOR 5th Asia-Pacific Conference
    • Place of Presentation
      Taipei,China Republic
    • Year and Date
      2012-09-24
    • Related Report
      2012 Final Research Report
  • [Presentation] Prospective Validation of Patient Neurotoxicity Questionnaire (PNQ) for Assessment of Oxaliplatin Neurotoxicty : CSP-HOR 162012

    • Author(s)
      Amano T, Shimada Y, Nishina T, ShinozakiK, Esaki T, Komatsu Y, Shimozuma K, Akita H, Ohashi Y, Hausheer FH
    • Organizer
      European Society for Medical Oncology
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2012 Final Research Report
  • [Presentation] Perception and clinical care of depression in breast cancer patients - a survey of oncology practice in Japan2012

    • Author(s)
      Sato I, Makino H, Shimozuma K, Ohashi Y
    • Organizer
      28th Meeting of the International Society for Pharmacoepidemiology
    • Place of Presentation
      Barcelona,Spain
    • Related Report
      2012 Final Research Report
  • [Presentation] Perception and clinical care of depression in breast cancer patients - a survey of oncology practice in Japan.2012

    • Author(s)
      Sato I
    • Organizer
      28th Meeting of the International Society for Pharmacoepidemiology
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2012 Annual Research Report
  • [Presentation] The margin between acquisition costs and reimbursement prices of generic drugs (Yakkasa) in Japan.2012

    • Author(s)
      Shibahara H
    • Organizer
      ISPOR 5th Asia-Pacific Conference
    • Place of Presentation
      Taipei, China Republic
    • Related Report
      2012 Annual Research Report
  • [Presentation] QALY and productivity loss: empirical evidence for “double counting”.2012

    • Author(s)
      Shiroiwa T
    • Organizer
      ISPOR 5th Asia-Pacific Conference
    • Place of Presentation
      Taipei, China Republic
    • Related Report
      2012 Annual Research Report
  • [Presentation] Prospective Validation of Patient Neurotoxicity Questionnaire (PNQ) for Assessment of Oxaliplatin Neurotoxicty : CSP-HOR 16.2012

    • Author(s)
      Amano T
    • Organizer
      European Society for Medical Oncology
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2012 Annual Research Report
  • [Presentation] Assessment of effects of response shift in palliative care patients using the structural equation modeling approach.

    • Author(s)
      Suzukamo Y
    • Organizer
      19th Annual Conference of the International Society for Quality of Life Research
    • Place of Presentation
      Budapest, Hungary
    • Related Report
      2012 Annual Research Report
  • [Presentation] Minimally important difference (MID) in scores on the European organization for research and treatment of cancer (EORTC) Quality of Life Questionnaire Core 15 for Palliative (QLQ-C15-PAL).

    • Author(s)
      Miyazaki K
    • Organizer
      19th Annual Conference of the International Society for Quality of Life Research
    • Place of Presentation
      Budapest, Hungary
    • Related Report
      2012 Annual Research Report
  • [Presentation] Efficacy, toxicity and quality of life in older patients with early-stage breast cancer treated with oral Tegafur-uracil or classical CMF (cyclophosphamide, methotrexate, and fluorouracil): an exploratory analysis of National Surgical Adjuvant Study for Breast Cancer (N-SAS BC) 01 Trial.

    • Author(s)
      Hara F
    • Organizer
      35th San Antonio Breast Cancer Symposium
    • Place of Presentation
      San Antonio, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Impact of preservation of the intercostobrachial nerve during axillary dissection on sensory change and health-related quality of life two years after breast cancer surgery.

    • Author(s)
      Taira N
    • Organizer
      35th San Antonio Breast Cancer Symposium
    • Place of Presentation
      San Antonio, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Comparison of bone health in continuation and stop groups after 5 years of anastrozole: NSAS-BC 05.

    • Author(s)
      Takei H
    • Organizer
      13th St. Gallen International Breast Cancer Conference
    • Place of Presentation
      St. Gallen, Switzerland
    • Related Report
      2012 Annual Research Report
  • [Book] 生命科学1-生物個体から分子へ 3.8 医療・福祉制度2012

    • Author(s)
      下妻晃二郎
    • Publisher
      コロナ社
    • Related Report
      2012 Final Research Report
  • [Book] 患者さんのための乳がん診療ガイドライン2012

    • Author(s)
      下妻晃二郎
    • Publisher
      金原出版
    • Related Report
      2012 Final Research Report
  • [Book] 生命科学1-生物個体から分子へ 3.8 医療・福祉制度2012

    • Author(s)
      下妻晃二郎
    • Publisher
      コロナ社
    • Related Report
      2012 Annual Research Report
  • [Book] 2012年版 患者さんのための乳がん診療ガイドライン2012

    • Author(s)
      日本乳癌学会
    • Publisher
      金原出版株式会社
    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.ritsumei.ac.jp/lifescience/bm/shimozuma/index.html

    • Related Report
      2012 Final Research Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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