| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
(1) As an animal model of "placebo-induced analgesia", the effects of non-opioid analgesic drugs were conditioned in rats and mice with inflammatory pain. We have established the new assessment system to evaluate the changes of spontaneous activity and emotions such as anxiety, in addition to pain thresholds.
(2) We have shown that the reduction of anxiety is conditioned simultaneously with analgesia, and that the prefrontal cortex and amygdala are involved in "placebo-induced analgesia." The study is still in progress.
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