| Project/Area Number |
24659332
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Public health/Health science
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| Research Institution | Osaka Medical College (2013)
Kinki University (2012) |
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Principal Investigator |
TAMAKI Junko 大阪医科大学, 医学部, 教授 (90326356)
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| Co-Investigator(Kenkyū-buntansha) |
IKI Masayuki 近畿大学, 医学部, 教授 (50184388)
SATO Yuho 仁愛大学, 生活科学学科, 教授 (10337115)
KOUDA Katsuyasu 近畿大学, 医学部, 准教授 (60273182)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
|
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| Keywords | 成人保健 / 骨折 / 循環器疾患 |
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| Research Abstract |
We conducted the 5-year follow-up survey of FORMEN Study which enrolled 2012 men at the baseline, as part of a prospective cohort study of Fujiwara-kyo study. There was no significant difference in esRAGE values at the baseline survey in men who suffered coronary artery diseases when compared to men who did not. The higher values of esRAGE were significantly correlated with the lower values of intima-media thickness of carotid artery (IMT) measured at the 5-year follow-up survey, while there was no significant correlation between esRAGE- to pentosidine ratio and IMT values. Higher values of esRAGE-to-pentosidine ratio were associated with a decreased risk of fragility fractures independently of age and BMD among Japanese elderly men.
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