clarification of the mechanism of proteinuria with conditional knockout mice
| Project/Area Number |
24659499
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | Okayama University |
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Principal Investigator |
KUNIHIKO AYA 岡山大学, 医学部, 客員研究員 (20379762)
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| Co-Investigator(Kenkyū-buntansha) |
OUCHIDA Mamoru 岡山大学, 大学院医歯薬学総合研究科, 准教授 (80213635)
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| Project Period (FY) |
2012-04-01 – 2013-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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| Keywords | 蛋白尿 / 細胞内輸送 / ポドシン / ネフリン / 腎炎 / ネフローゼ / ポドサイト / 輸送蛋白 |
|---|
| Research Abstract |
To clarify the mechanism of proteinuria, we identified the transport protein which binds to podocin and expresses in podocyte on previous grant-in-aid. We made podocyte-specific conditional knockout mice to examine the in-vivo function of this molecule and start analysis on this grant-in-aid.
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Report
(3 results)
Research Products
(9 results)
