• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

A clinical and neuroimaging study of adolescents with autism spectrum disorder or bipolar disorders

Research Project

Project/Area Number 24659541
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Psychiatric science
Research InstitutionKanazawa University

Principal Investigator

MUNESUE Toshio  金沢大学, 子どものこころの発達研究センター, 特任教授 (50293353)

Co-Investigator(Kenkyū-buntansha) KIKUCHI Mitsuru  金沢大学, 子どものこころの発達研究センター, 特任教授 (00377384)
YOSHIMURA Yuko  金沢大学, 子どものこころの発達研究センター, 協力研究員 (70597070)
SHITAMICHI Kiyomi  金沢大学, 子どものこころの発達研究センター, 協力研究員 (70569475)
UENO Sanae  金沢大学, 子どものこころの発達研究センター, 協力研究員 (80569476)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords双極性障害 / 自閉症 / 児童青年精神医学 / 児童青年期精神医学
Outline of Final Research Achievements

We performed psychological assessments including Autism-spectrum Quotient, Rorchach test and Dimensional Yale-Brown Obsessive-Compulsive Scale to subjects with bipolar disorder or autism spectrum disorder, and typically developing individuals. Results suggested that there may be common pathological bases between bipolar disorder and autism spectrum disorder.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (19 results)

All 2013 2012 Other

All Journal Article (14 results) (of which Peer Reviewed: 14 results) Presentation (2 results) (of which Invited: 1 results) Book (2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Episodic memory retrieval for story characters in high-functioning autism2013

    • Author(s)
      Komeda H, Kosaka H, Saito DN, Inohara K, Munesue T, Ishitobi M, Sato M, Okazawa H.
    • Journal Title

      Mol Autism

      Volume: 4 (1) Issue: 1 Pages: 20-20

    • DOI

      10.1186/2040-2392-4-20

    • NAID

      120005293585

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Non-synonymous single-nucleotide variations of the human oxytocin receptor gene and autism spectrum disorders: a case-control study in a Japanese population and functional analysis.2013

    • Author(s)
      Ma WJ, Hashii M, Munesue T, Hayashi K, Yagi K, Yamagishi M, Higashida H, Yokoyama S.
    • Journal Title

      Mol Autism

      Volume: 4 Issue: 1 Pages: 22-22

    • DOI

      10.1186/2040-2392-4-22

    • NAID

      120006325350

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Atypical brain lateralisation in the auditory cortex and language performance in 3- to 7-year-old children with high-functioning autism spectrum disorder : a child-customised magnetoencephalography (MEG) study2013

    • Author(s)
      Y Yoshimura, M Kikuchi, K Shitamichi, S Ueno, T Munesue, Y Ono, T Tsubokawa, Y Haruta, M Oi, Y Niida, GB Remijn, T Takahashi, M Suzuki, H Higashida, Y Minabe
    • Journal Title

      Mol Autism

      Volume: 8巻 Issue: 1 Pages: 38-38

    • DOI

      10.1186/2040-2392-4-38

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Altered brain connectivity in 3-to-7-year-old children with autism spectrum disorder.2013

    • Author(s)
      Kikuchi, M., Shitamichi, K., Yoshimura, Y., Ueno, S., et al., Remijn, G.B., Takahashi, T., Suzuki, M., Higashida, H., Minabe, Y.
    • Journal Title

      Neuroimage: Clinical

      Volume: 2 Pages: 394-401

    • DOI

      10.1016/j.nicl.2013.03.003

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] The brain's response to the human voice depends on the incidence of autistic traits in the general population2013

    • Author(s)
      Y Yoshimura, M Kikuchi, S Ueno, E Okumura, H Hiraishi, C Hasegawa, G B Remijn, K Shitamichi, T Munesue, T Tsubokawa, H Higashida, Y Minabe
    • Journal Title

      PLoS One

      Volume: 20巻 Issue: 11 Pages: e80126-e80126

    • DOI

      10.1371/journal.pone.0080126

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Visual perception of unstructured figures in patients with autism spectrum disorder: A preliminary study2013

    • Author(s)
      Muramatsu T, Nakatani H, Kikuchi M, Munesue T
    • Journal Title

      J Brain Sci

      Volume: 40 Pages: 5-27

    • NAID

      110009612495

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] A custom Magnetoencephalography device reveals brain connectivity and high reading/decoding ability in children with autism.2013

    • Author(s)
      Kikuchi, M., Yoshimura, Y., Shitamichi, K., Ueno, S., et al., Remijn, G.B., Takahashi, T., Suzuki, M., Higashida, H., Minabe, Y.
    • Journal Title

      Scientific Reports

      Volume: 3 Issue: 1 Pages: 1139-1139

    • DOI

      10.1038/srep01139

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Anterior prefrontal hemodynamic connectivity in conscious 3- to 7-year-old children with typical development and autism spectrum disorder.2013

    • Author(s)
      Kikuchi, M., Yoshimura, Y., Shitamichi, K., Ueno, S., et al., Remijn, G.B., Takahashi, T., Suzuki, M., Higashida, H., Minabe, Y.
    • Journal Title

      PloSONE

      Volume: 8 Issue: 2 Pages: 56087-56087

    • DOI

      10.1371/journal.pone.0056087

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Social memory, amnesia, and autism : brain oxytocin secretion is regulated by NAD+ and single nucleotide polymorphism of CD382012

    • Author(s)
      Higashida, H
    • Journal Title

      Neurochem Int

      Volume: (in press) Issue: 6 Pages: 828-838

    • DOI

      10.1016/j.neuint.2012.01.030

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Language performance and auditory evoked fields in 2- to 5-year-old children2012

    • Author(s)
      Yoshimura, Y., Kikuchi, M., Shitamichi, K., Ueno, S., Remijn, G.B., et al
    • Journal Title

      European Journal of Neuroscience

      Volume: 35 Issue: 4 Pages: 644-650

    • DOI

      10.1111/j.1460-9568.2012.07998.x

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Spatiotemporal frequency characteristics of cerebral oscillations during the perception of fundamental frequency contour changes in one-syllable intonation2012

    • Author(s)
      Ueno S, Okumura E, Remijn GB, YoshimuraY, Kikuchi M, Shitamichi K, Nagao K, Mochiduki M, Haruta Y, Hayashi N, Munesue T, Tsubokawa T, Oi M, NakataniH, Higashida H, MinabeY.
    • Journal Title

      Neurosci Lett

      Volume: (in press) Issue: 2 Pages: 141-146

    • DOI

      10.1016/j.neulet.2012.03.031

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Oxytocin attenuates feelings of hostility depending on emotional context and individuals' characteristics2012

    • Author(s)
      Tetsu Hirosawa1, Mitsuru Kikuchi, Haruhiro Higashida, Eiichi Okumura, Sanae Ueno, Kiyomi Shitamichi, YukoYoshimura, Toshio Munesue, TsunehisaTsubokawa, Yasuhiro Haruta, Hideo Nakatani, Takanori Hashimoto, Yoshio Minabe
    • Journal Title

      Scientific Reports

      Volume: (in press) Issue: 1 Pages: 384-384

    • DOI

      10.1038/srep00384

    • NAID

      120005821069

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Long-term oxytocin administration improves social behaviors in a girl with autistic disorder2012

    • Author(s)
      Kosaka H et al.,
    • Journal Title

      BMC Psychiatry

      Volume: 12(1) Issue: 1 Pages: 110-110

    • DOI

      10.1186/1471-244x-12-110

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Hard to "tune in" : neural mechanisms of live face-to-face interaction with high-functioning autistic spectrum disorder2012

    • Author(s)
      Tanabe HC, Kosaka H, Saito DN, Koike T, Hayashi MJ, Izuma K, Komeda H, Ishitobi M, Omori M, Munesue T, Okazawa H, Wada Y, Sadato N
    • Journal Title

      Front Hum Neurosci

      Volume: 6 Pages: 268-268

    • DOI

      10.3389/fnhum.2012.00268

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] シンポジウム「児童青年期の気分障害」:青年期の気分障害を双極性障害から考える

    • Author(s)
      棟居俊夫
    • Organizer
      第10回日本うつ病学会
    • Place of Presentation
      小倉・北九州国際会議場
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 青年期双極性障害における強迫症状の自閉症傾向との関連

    • Author(s)
      棟居俊夫、菊知充、三邉義雄
    • Organizer
      第40回日本脳科学会
    • Place of Presentation
      浜松・アクトシティ浜松
    • Related Report
      2013 Research-status Report
  • [Book] こころの病気を学ぶ2013

    • Author(s)
      棟居俊夫
    • Total Pages
      268
    • Publisher
      シナジー
    • Related Report
      2013 Research-status Report
  • [Book] Neuroendocrinology and Behavior2012

    • Author(s)
      Tomiki Sumiyoshi
    • Total Pages
      164
    • Publisher
      InTech
    • Related Report
      2012 Research-status Report
  • [Patent(Industrial Property Rights)] 自閉症スペクトラムの検査方法及びオキシトシン投与による自閉症スペクトラムの治療効果を予測する方法2013

    • Inventor(s)
      横山茂、棟居俊夫
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-03-05
    • Related Report
      2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi