Analysis for disease mechanism by intracellular elements using microparticle beam

• Project/Area Number: 24659556
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Single-year Grants
• Research Field: Radiation science
• Research Institution: University of Tsukuba
• Principal Investigator: SAKURAI Hideyuki 筑波大学, 医学医療系, 教授 (50235222)
• Project Period (FY): 2012-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 量子ビーム

Research Abstract

In the present generation, the trace elements are taken in human body and these cause several disease. The trace elements have shown close correlation of treatment resistant disease, such as Parkinson disease. In cancer therapy, some trace elements are used as an anticancer agent. In this research, mechanisms of disease & treatment effect are analyzed by measuring trace element distribution in cell. In analysis for sample from atypical pneumonia, many elements, such as iron, nickel, chromium, aluminium, were seen simultaneously as one image. By using cultured cells in vitro, uptake of cis-platinum to cells were seen, and amount of platinum could be estimated. This study is useful for scientific diagnosis for treatment resistant disease in recent society.

Research Products

• [Journal Article] Outcomes and prognostic factors for recurrence after high-dose proton beam therapy for centrally and peripherally located stage I non-small-cell lung cancer (2014)
  • Author(s): Kanemoto A, Okumura T, Ishikawa H, Mizumoto M, Oshiro Y, Kurishima K, Homma S, Hashimoto T, Ohkawa A, Numajiri H, Ohno T, Moritake T, Tsuboi K, Sakae T, Sakurai H
  • Journal Title: Clin Lung Cancer Volume: 15
  • DOI: 10.1016/j.cllc.2013.11.002
  • Peer Reviewed
• [Journal Article] Isolated solitary brain metastasis as a relapse of small cell lung cancer (2013)
  • Author(s): Sakurai H, Kurishima K, 他6名
  • Journal Title: Oncol Lett Volume: 6(4) Pages: 1108-1110
  • DOI: 10.3892/ol.2013.1489
  • NAID: 120005516381
• [Journal Article] A phase I study on combined therapy with proton-beam radiotherapy and in situ tumor vaccination for locally advanced recurrent hepatocellular carcinoma. (2013)
  • Author(s): Abei M, Okumura T, Fukuda K, Hashimoto T, Araki M, Ishige K, Hyodo I, Kanemoto A, Numajiri H, Mizumoto M, Sakae T, Sakurai H, Zenkoh J, Ariungerel G, Sogo Y, Ito A,Ohno T, Tsuboi K
  • Journal Title: Radiation Oncology Volume: 16 Pages: 239-239
  • DOI: 10.1186/1748-717x-8-239
  • Peer Reviewed
• [Journal Article] Evaluation of vegetables in Tsukuba for contamination with radioactive materials from the accident at Fukushima Daiichi nuclear power plant (2013)
  • Author(s): Isobe T, Mori Y, Takada K, Sato E, Takahashi H, Sekiguchi T, Yoshimura Y, Sakurai H, Sakae T
  • Journal Title: Health Phys Volume: 105 Pages: 311-317
  • DOI: 10.1097/hp.0b013e3182895759
  • Peer Reviewed
• [Journal Article] Reirradiation for recurrent malignant brain tumor with radiotherapy or proton beam therapy. Technical considerations based on experience at a single institution. (2013)
  • Author(s): Mizumoto M, Okumura T, Ishikawa E, Yamamoto T, Takano S, Matsumura A, Oshiro Y, Ishikawa H, Sakurai H, Tsuboi K
  • Journal Title: Strahlentherapie und Onkologie Volume: 189 Pages: 656-63
  • DOI: 10.1007/s00066-013-0390-6
  • Peer Reviewed
• [Journal Article] The use of proton-beam therapy in the treatment of nsclc (2013)
  • Author(s): Oshiro Y, Sakurai H
  • Journal Title: Exp Rev Med Devices Volume: 10(2) Pages: 239-45
  • DOI: 10.1586/erd.12.81
  • Peer Reviewed
• [Journal Article] Proton beam therapy for malignancy in bloom syndrome (2013)
  • Author(s): Mizumoto M, Hashii H, Senarita M, Sakai S, Wada T, Okumura T, Tsuboi K, Sakurai H
  • Journal Title: Strahlentherapie und Onkologie Volume: 189 Pages: 335-337
  • DOI: 10.1007/s00066-012-0274-1
  • Peer Reviewed
• [Journal Article] Robust technique using an imaging plate to detect environmental radioactivity (2013)
  • Author(s): Isobe T, Mori Y, 他4名
  • Journal Title: Health Phys Volume: 104(4) Pages: 362-5
  • DOI: 10.1097/hp.0b013e31827d41a9
• [Journal Article] Incidence of venous thromboembolism before treatment in cervical cancer and the impact of management OD venous thromboembolism after commencement of treatment (2013)
  • Author(s): Toyomi Satoh, Koji Matsumoto, Yumiko O Tanaka, Azusa Akiyama, Sari Nakao, Manabu Sakurai, Hiroyuki Ochi, Mamiko Onuki, Takeo Minaguchi, Hideyuki Sakurai, Hiroyuki Yoshikawa.
  • Journal Title: Thromb Res Volume: 131(4)
  • DOI: 10.1016/j.thromres.2013.01.027
  • Peer Reviewed
• [Journal Article] Dose-volume histogram analysis for risk factors of radiation-induced rib fracture after hypofractionated proton beam therapy for hepatocellular carcinoma (2013)
  • Author(s): Kanemoto A, Mizumoto M, Okumura T, Takahashi H, Hashimoto T, Oshiro Y, Fukumitsu N, Moritake T, Tsuboi K, Sakae T, Sakurai H
  • Journal Title: Acta Oncol Volume: 52(3) Pages: 538-44
  • DOI: 10.3109/0284186x.2012.718094
  • Peer Reviewed
• [Journal Article] Lineal energy-based evaluation of oxidative DNA damage induced by proton beams and X-rays. (2013)
  • Author(s): Zhengshan Hong, Yuki Kase, Takashi Moritake, Ariungerel Gerelchuluun, Lue Sun, Kenshi Suzuki, Toshiyuki Terunuma, Kiyoshi Yasuoka, Hiroaki Kumada, Kazunori Anzai, Hideyuki Sakurai, Takeji Sakae and Koji Tsuboi
  • Journal Title: Int J Radiat Biol. Volume: Vol.89 Pages: 36-43
  • DOI: 10.3109/09553002.2012.715791
  • Peer Reviewed
• [Journal Article] Comparison of the effects of high-energy photon beam irradiation (10 and 18 mv) on 2 types of implantable cardioverter-defibrillators (2013)
  • Author(s): Hashii H, Hashimoto T, Okawa A, Shida K, Isobe T, Hanmura M, Nishimura T, Aonuma K, Sakae T, Sakurai H
  • Journal Title: Int J Radiat Oncol Volume: 85 Pages: 840-5
  • DOI: 10.1016/j.ijrobp.2012.05.043
  • Peer Reviewed
• [Journal Article] Clinical results of proton beam therapy for advanced neuroblastoma (2013)
  • Author(s): Oshiro Y, Mizumoto M, Okumura T, Sugahara S, Fukushima T, Ishikawa H, Nakao T, Hashimoto T, Tsuboi K, Ohkawa H, Kaneko M, Sakurai H
  • Journal Title: Radiat Oncol Volume: 12 Pages: 142-142
  • DOI: 10.1186/1748-717x-8-142
  • NAID: 120005312266
  • Peer Reviewed
• [Journal Article] Multidisciplinary therapy including proton beam radiotherapy for a Ewing sarcoma family tumor of maxillary sinus in a 4-year-old girl (2013)
  • Author(s): Yamaoka M, Akiyama M, Yokokawa Y, Terao Y, Yokoi K, Kato T, Fukushima T, Sakurai H, Ida H
  • Journal Title: Head Neck Volume: 35
  • DOI: 10.1002/hed.23352
  • Peer Reviewed
• [Journal Article] Proton beam therapy for unresectable hepatoblastoma in children: survival in one case. (2013)
  • Author(s): Oshiro Y, Okumura T, Mizumoto M, Fukushima T, Ishikawa H, Hashimoto T, Tsuboi K, Kaneko M, Sakurai H
  • Journal Title: Acta Oncologica Volume: 52(3) Pages: 600-3
  • DOI: 10.3109/0284186x.2012.760849
  • Peer Reviewed
• [Journal Article] Comparison of adverse effects of proton and X-ray chemoradiotherapy for oesophageal cancer using an adaptive dose-volume histogram analysis (2013)
  • Author(s): Makishima H, Ishikawa H, Terunuma T, Hashimoto T, Yamanashi K, Sekiguchi T, Mizumoto M, Okumura T, Tsuboi K, Sakurai H
  • Journal Title: Eur J Cancer Volume: 49
  • Peer Reviewed
• [Journal Article] Proton beam therapy for a patient with large rhabdomyosarcoma of the body trunk (2013)
  • Author(s): Takizawa D, Oshiro Y, Okumura T, Mizumoto M, Fukushima T, Ishikawa H, Tsuboi K, Kaneko M, Sakurai H
  • Journal Title: Pediatr Blood Cancer Volume: 60 Pages: 93-93
  • Peer Reviewed
• [Journal Article] Prognosis was not deteriorated by multiple primary cancers in esophageal cancer patients treated by radiotherapy. (2013)
  • Author(s): Shirai K, Tamaki Y, Kitamoto Y, et al
  • Journal Title: J Radiat Res Volume: (In press) Pages: 706-711
  • DOI: 10.1093/jrr/rrt002
  • Peer Reviewed
• [Journal Article] Investigation of the geometric accuracy of proton beam irradiation in the liver (2012)
  • Author(s): Fukumitsu N, Hashimoto T, Okumura T, et al.
  • Journal Title: Int J Radiat Oncol Biol Phys Volume: 82 Pages: 826-33
  • DOI: 10.1016/j.ijrobp.2010.10.028
  • Peer Reviewed
• [Journal Article] Reproducibility of image quality for moving objects using respiratory-gated computed tomography : a study using a phantom model (2012)
  • Author(s): Fukumitsu N, Ishida M, Terunuma T., et al
  • Journal Title: J Radiat Res Volume: 53 Pages: 945-53
  • DOI: 10.1093/jrr/rrs039
  • Peer Reviewed
• [Journal Article] Outcome of T4 (International Union Against Cancer Staging System, 7th edition) or recurrent nasal cavity and paranasal sinus carcinoma treated with proton beam (2012)
  • Author(s): Fukumitsu N, Okumura T, 他12名
  • Journal Title: Int J Radiat Oncol Biol Phys Volume: (in press) Pages: 704-11
  • DOI: 10.1016/j.ijrobp.2011.07.032
  • Peer Reviewed
• [Journal Article] Verification of beam delivery using fibrosis after proton beam irradiation to the lung tumor (2012)
  • Author(s): Fukumitsu N, Oshiro Y, 他7名
  • Journal Title: Lung Cancer Volume: (in press) Pages: 83-8
  • DOI: 10.1016/j.lungcan.2012.01.007
  • NAID: 120004442317
  • Peer Reviewed
• [Journal Article] Influence of secondary neutrons induced by proton radiotherapy for cancer patients with implantable cardioverter defibrillators (2012)
  • Author(s): Hashimoto T, Isobe T, 他8名
  • Journal Title: Radiat Oncol Volume: 7 Pages: 10-10
  • DOI: 10.1186/1748-717x-7-10
  • NAID: 120003958833
  • Peer Reviewed
• [Journal Article] Advances in highly conformal radiotherapy for prostate cancer : past, current, and future (2012)
  • Author(s): Ishikawa H, Hashimoto T, 他4名
  • Journal Title: Igaku Butsuri Volume: 32(3) Pages: 138-47
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/24592684
• [Journal Article] Proton beam therapy for inoperable recurrence of bronchial high-grade mucoepidermoid carcinoma (2012)
  • Author(s): Kanemoto A, Oshiro Y, Sugahara S, Kamagata S, Hirobe S, Toma M, Okumura T, Sakurai H
  • Journal Title: Jpn J Clin Oncol Volume: 42(6) Pages: 552-5
  • DOI: 10.1093/jjco/hys047
  • Peer Reviewed
• [Journal Article] Evaluation of liver function after proton beam therapy for hepatocellular carcinoma (2012)
  • Author(s): Mizumoto M, Okumura T, 他15名
  • Journal Title: Int J Radiat Oncol Biol Phys Volume: 82
  • DOI: 10.1016/j.ijrobp.2011.05.056
  • Peer Reviewed
• [Journal Article] Designed-seamless irradiation technique for extended whole mediastinal proton-beam irradiation for esophageal cancer (2012)
  • Author(s): Okonogi N, Hashimoto T, 他6名
  • Journal Title: Radiat Oncol Volume: 7 Pages: 173-173
  • DOI: 10.1186/1748-717x-7-173
  • NAID: 120005174012
• [Journal Article] Analysis of intravesical recurrence after bladder-preserving therapy for muscle-invasive bladder cancer (2012)
  • Author(s): Onozawa M, Miyazaki J, Kawai K, Nishiyama H
  • Journal Title: Jpn J Clin Oncol Volume: 42(9) Pages: 825-30
  • DOI: 10.1093/jjco/hys105
  • Peer Reviewed
• [Journal Article] Results of proton beam therapy without concurrent chemotherapy for patients with unresectable stage III non-small cell lung cancer (2012)
  • Author(s): Oshiro Y, Mizumoto M, 他10名
  • Journal Title: J Thorac Oncol Volume: 7 Pages: 370-375
  • DOI: 10.1097/jto.0b013e31823c485f
  • Peer Reviewed
• [Presentation] 陽子線治療の臨床と今後の動向 (2014)
  • Author(s): 櫻井英幸
  • Organizer: 第3回岡山粒子線治療研究会
  • Place of Presentation: 岡山
  • Invited
• [Presentation] Suprasellar GCT and endocrinopathy;duration of symptoms and outcome (2013)
  • Author(s): Fukushima H, et al
  • Organizer: 第55回日本小児血液・がん学会学術集会/第11回日本小児がん看護学会/第18回公益財団法人がんの子どもを守る会公開シンポジウム
  • Place of Presentation: 福岡
• [Presentation] Multidisciplinary therapy including proton beam therapy for Ewing's sarcoma family of tumors (2013)
  • Author(s): Suzuki R, et al
  • Organizer: 第55回日本小児血液・がん学会学術集会/第11回日本小児がん看護学会/第18回公益財団法人がんの子どもを守る会公開シンポジウム
  • Place of Presentation: 福岡
• [Presentation] Comparison of adverse effects proton and X-ray chemoradiotherapy for oesophageal cancer using an adaptive dose-volume histogram (2013)
  • Author(s): Makishima H, et al
  • Organizer: The European Cancer Congress 2013
  • Place of Presentation: Amsterdam, Holland
• [Presentation] Proton beam therapy for a patient with large rhabdomyosarcoma of the body trunk (2013)
  • Author(s): Takizawa D, et al
  • Organizer: 45th Congress of the International Society of Paediatric Oncology
  • Place of Presentation: Hong Kong, China
• [Presentation] Proton beam therapy for pediatric patients with pediatric ependymoma (2013)
  • Author(s): Mizumoto M, et al
  • Organizer: 45th Congress of the International Society of Paediatric Oncology
  • Place of Presentation: Hong Kong, China
• [Presentation] Verfication of the new BNCT treatment planning system in Tokyo (2013)
  • Author(s): Yamanashi K, et al
  • Organizer: 7th Young Researchers' Boron Neutron Capture Therapy Meeting
  • Place of Presentation: Granada, Spain
• [Presentation] Boron-neutron capture therapy for newly diagnosed head and neck cancer in initial treatment (2013)
  • Author(s): Aihara T, et al
  • Organizer: 7th Young Researchers BNCT Meeting
  • Place of Presentation: Granada, Spain
• [Presentation] Long-term survival in patients with hepatocellular carcinoma initially treated with definitive proton beam therapy (2013)
  • Author(s): Okumura T, et al
  • Organizer: 55th Anuual Meeting of the American Society for Radiation Oncology(ASTRO2013)
  • Place of Presentation: Atlanta, Georgia
• [Presentation] Preliminary results of concurrent chemoradiation therapy using proton beam therapy for esophageal cancer (2013)
  • Author(s): Ishikawa H, et al
  • Organizer: 55th Anuual Meeting of the American Society for Radiation Oncology(ASTRO 2013)
  • Place of Presentation: Atlanta, Georgia
• [Presentation] Boron-neutron capture therapy for advanced maxillary sinus cancer : two case reports (2013)
  • Author(s): Aihara T, et al
  • Organizer: 16th Asian Research Symposium in Rhinology
  • Place of Presentation: Tokyo, Japan
• [Presentation] Verfication of the new BNCT treatment planning system in Tokyo (2013)
  • Author(s): K Yamanashi,H Kumada,K Takada,H Sakurai,T Sakae
  • Organizer: 7th Young Researchers' Boron Neutron Capture Therapy Meeting
  • Place of Presentation: Granada,Spain
• [Presentation] The basic evaluation of radiation exposure dose for whole body in clinical boron neutron capture therapy (2013)
  • Author(s): K Takada,T Isobe,H Kumada,K Yamanashi,H Sakurai,T Sakae
  • Organizer: The 69th Scientific Assembly of the JSRT Creation, Innovation, Globalization(日本放射線技術学会第69回総会学術大会）
  • Place of Presentation: Yokohama, Japan
• [Presentation] Multidisciplinary therapy including proton beam therapy for Ewing's sarcoma family of tumors. (2013)
  • Author(s): R Suzuki,T Fukushima,C Kobayashi,H Fukushima,A Sakai,T Ishida,T Ohsumi,H Ochiai,S Kishimoto,M Chin,R Hosogai,Y Hosoya,A Watanabe,C Goto,K Masumoto,M Mizumoto,H Sakurai,R Sumazaki
  • Organizer: 第55回日本小児血液・がん学会学術集会/第11回日本小児がん看護学会/第18回公益財団法人がんの子どもを守る会公開シンポジウム
  • Place of Presentation: 福岡
• [Presentation] Long-term survival in patients with hepatocellular carcinoma initially treated with definitive proton beam therapy (2013)
  • Author(s): T Okumura,K Fukuda,T Hashimoto,M Mizumoto,H Ishikawa,T Sakae,M Abei,K Tsuboi,H Sakurai
  • Organizer: 55th Anuual Meeting of the American Society for Radiation Oncology(ASTRO2013).
  • Place of Presentation: Atlanta, USA
• [Presentation] Quantitative assessment of 131-1 in soil originating from the Fukushima Daiichi Nuclear Power Plant Disaster using a germanium semiconductor detector (2013)
  • Author(s): Y Mori,T Isobe,K Takada,S Kamizawa,E Sato,H Sakurai,T Sakae
  • Organizer: The Fourth International Symposium on Innovative Nuclear Energy Systems(INES-4)
  • Place of Presentation: Tokyo, Japan
• [Presentation] Preliminary results of concurrent chemoradiation therapy using proton beam therapy for esophageal cancer (2013)
  • Author(s): H Ishikawa,T Hashimoto,M Mizumoto,H Makishima,D Takizawa,Kaori Sugawara,T Okumura,H Sakurai
  • Organizer: 55th Anuual Meeting of the American Society for Radiation Oncology(ASTRO 2013)
  • Place of Presentation: Atlanta, USA
• [Presentation] Boron-neutron capture therapy for advanced maxillary sinus cancer: two case reports (2013)
  • Author(s): Teruhito Aihara,Norimasa Morita,Hiroaki Kumada,Hitoshi Ishikawa,Nobuhiko Kamitani,Nobuyoshi Fukumitsu,Yoshinori Sakurai,Junichi Hitatsuka,Hideyuki Sakurai
  • Organizer: 16th Asian Research Symposium in Rhinology
  • Place of Presentation: Tokyo, Japan
• [Presentation] Boron-neutron capture therapy for newly diagnosed head and neck cancer in initial treatment (2013)
  • Author(s): T Aihara,N Morita,N Kamitani,H Kumada,N Fukumitsu,Y Sakurai,K Ohnishi, ,J Hiratsuka,H Sakurai
  • Organizer: 7th Young Researchers BNCT Meeting
  • Place of Presentation: Guranada, Spain
• [Presentation] 切除不能篩骨洞扁平上皮癌に対する陽子線治療の初期経験 (2013)
  • Author(s): 斎藤高,石川仁,水本斉志,福光延吉,奥村敏之,櫻井英幸
  • Organizer: 第37回日本頭頸部癌学会
  • Place of Presentation: 東京
• [Presentation] 食道扁平上皮癌に対する同時化学療法併用陽子線治療成績 (2013)
  • Author(s): 石川仁,橋本孝之,奥村敏之,大野豊然貴,森脇俊和,久倉勝治,寺島秀夫,櫻井英幸
  • Organizer: 第67回日本食道学会学術集会
  • Place of Presentation: 大阪
• [Presentation] 筑波大学の陽子線治療の現状と目指すべきもの (2013)
  • Author(s): 櫻井英幸,石川仁,奥村敏之
  • Organizer: 第72回日本医学放射線学会総会
  • Place of Presentation: 横浜
  • Invited
• [Presentation] 陽子線治療と中性子捕捉療法の過去、現在、未来 －難治癌克服に向けて- (2013)
  • Author(s): 櫻井英幸,奥村敏之,石川仁,福光延吉,粟飯原輝人,大西かよ子,水本斉志,大城佳子,沼尻晴子,熊田博明,坪井康次
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 子宮頸癌：画像誘導ブラキセラピーの動向 (2013)
  • Author(s): 櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
  • Invited
• [Presentation] 当院における前立腺癌高リスク群に対する３DCRTの治療成績 (2013)
  • Author(s): 牧島弘和,林靖孝,新田和範,清水誠,青木誠,相澤健太郎,海老根聖子,奥村敏之,櫻井英幸,玉木義雄
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 局所進行非小細胞肺癌に対する化学療法併用陽子線治療の安全性、有効性試験の初期報告 (2013)
  • Author(s): 大城佳子,奥村敏之,水本斉志,栗島浩一,石川仁,大川綾子,沼尻晴子,金本彩恵,大野豊然貴,牧島弘和,櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 食道扁平上皮癌に対する同時化学療法併用陽子線治療成績 (2013)
  • Author(s): 石川仁,大野豊然貴,橋本孝之,水本斉志,大西かよ子,粟飯原輝人,沼尻晴子,福光延吉,奥村敏之,櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 小児頭蓋内上衣腫に対する陽子線治療 (2013)
  • Author(s): 水本斉志,瀧澤大地,大城佳子,沼尻晴子,大西かよ子,福光延吉,石川仁,奥村敏之,坪井康次,櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 前立腺がん陽子線治療におけるリスク臓器線量低下を目的としたビーム方向の検討 (2013)
  • Author(s): 瀬川達矢,神澤聡,布施拓,照沼利之,榮武二,石川仁,櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 転移性肺腫瘍に対する陽子線治療成績 (2013)
  • Author(s): 大西かよ子,奥村敏之,石川仁,水本斉志,沼尻晴子,福光延吉,粟飯原輝人,坪井康次,櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 切除不能篩骨洞扁平上皮癌に対する陽子線治療の初期経 (2013)
  • Author(s): 斎藤高,石川仁,水本斉志,大西かよ子,福光延吉,粟飯原輝人,奥村敏之,櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 胆管ステントがCTV内にある肝胆膵悪性腫瘍に対する陽子線治療の経験 (2013)
  • Author(s): 大野豊然貴,奥村敏之,布施拓,牧島弘和,瀧澤大地,菅原香織,水本斉志,石川仁,榮武二,櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 陽子線治療を施行した前立腺基底細胞癌の１例 (2013)
  • Author(s): 中村智則,石川仁,瀧澤大地,沼尻晴子,水本斉志,大西かよ子,粟飯原輝人,福光延吉,坪井康次,奥村敏之,櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 頸部のデスモイド腫瘍に対して陽子線治療を施行した一例 (2013)
  • Author(s): 田中圭一,奥村敏之,水本斉志,大西かよ子,石川仁,粟飯原輝人,沼尻晴子,福光延吉,坪井康次,櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 婦人科領域癌の骨盤内再発腫瘍に対する組織内照射 (2013)
  • Author(s): 沼尻晴子,大川綾子,瀧澤大地,牧島弘和,大野豊然貴,水本斉志,大西かよ子,石川仁,奥村敏之,櫻井英幸
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 筑波大学のＢＮＣＴ臨床研究再開計画について (2013)
  • Author(s): 粟飯原輝人,山本哲哉,熊田博明,中井啓,石川仁,福光延吉,奥村敏之,大西かよ子,水本斉志,沼尻晴子,大野豊然貴,瀧澤大地,菅原香織,松村明,櫻井英幸
  • Organizer: 第10回日本中性子捕捉療法学会学術大会
  • Place of Presentation: 岡山
• [Presentation] 頭頸部進行癌における初期治療としての硼素中性子捕捉療法 (2013)
  • Author(s): 粟飯原輝人,森田倫正,神谷伸彦,熊田博明,福光延吉,鈴木実,櫻井良憲,小野公二,櫻井英幸,平塚純一
  • Organizer: 第10回日本中性子捕捉療法学会学術大会
  • Place of Presentation: 岡山
• [Presentation] 原発性肝癌の陽子線治療 (2013)
  • Author(s): 奥村敏之,橋本孝之,福田邦明,安部井誠人,福光延吉,水本斉志,沼尻晴子,大西かよ子,石川仁,坪井康次,福永潔,大河内信弘,櫻井英幸
  • Organizer: 第51回日本癌治療学会学術集会
  • Place of Presentation: 京都
• [Presentation] 頭頸部進行がんに対する初期治療としての硼素中性子捕捉療法 (2013)
  • Author(s): 粟飯原輝人,森田倫正,神谷伸彦,熊田博明,福光延吉,櫻井良憲,鈴木実,平塚純一,櫻井英幸
  • Organizer: 第51回日本癌治療学会学術集会
  • Place of Presentation: 京都
• [Presentation] Proton beam therapy at University of Tsukuba -present & future- (2012)
  • Author(s): Sakurai H
  • Organizer: 15th International Congress on Neutron Capture Therapy(ICNCT-15)
  • Place of Presentation: Tsukuba,Japan
  • Year and Date: 2012-09-10
• [Presentation] Proton beam therapy for cancer treatment at Tsukuba (2012)
  • Author(s): Sakurai H
  • Organizer: International Seminer for Fumding Program for World-Leading Innovative R&D on Science and Technology
  • Place of Presentation: Sapporo, Japan
  • Year and Date: 2012-07-24
• [Presentation] Simulation of the Secondary Radiation Dose in Boron Neutron Capture Therapy (2012)
  • Author(s): Takada K, et al
  • Organizer: RSNA 98th Scientific Assembly and Annual Meeting of North America
  • Place of Presentation: Chicago, USA
• [Presentation] The proposal of radiotherapy planning system for BNCT in consideration of an exposed dose to whole body (2012)
  • Author(s): Takada K, et al
  • Organizer: 15th International Congress on Neutron Capture Therapy
  • Place of Presentation: Tsukuba, Japan
• [Presentation] Evaluation of the radiation dose for whole body in boron neutron capture therapy (2012)
  • Author(s): Takada K, et al
  • Organizer: 12th International Conference on Radiation Shielding & 17th Topical Meeting of the Radiation Protection and Shielding Division of ANS
  • Place of Presentation: Nara,Japan
• [Presentation] Reduction of heat sensation of a patient using the silicone gel (2012)
  • Author(s): Kobayashi D, et al
  • Organizer: The 11th Intenational Congress of Hyperthermic Oncolgy/The 29th Japanease Congress of Thermal Medicine (ICHO & JCTM 2012)
  • Place of Presentation: Kyoto, Japan
• [Presentation] The optimal heating method for superficial tumors (2012)
  • Author(s): Takada K, et al
  • Organizer: The 11th Intenational Congress of Hyperthermic Oncolgy/The 29th Japanease Congress of Thermal Medicine(ICHO & JCTM 2012)
  • Place of Presentation: Kyoto, Japan
• [Presentation] Simulation of dose decrease effect for gated fluoroscopic imaging of tumor tracking system (2012)
  • Author(s): Terunuma T, et al
  • Organizer: The 31st Sapporo International Cancer Symposium 2012
  • Place of Presentation: Sapporo,Japan
• [Presentation] A supporting system for determination of patient calibration constants at PMRC in proton beam therapy (2012)
  • Author(s): Yasuoka K, et al
  • Organizer: The 31st Sapporo International Cancer Symposium 2012
  • Place of Presentation: Sapporo,Japan
• [Presentation] Cell inactivation ability and mechanish of clinical high-energy proton beams (2012)
  • Author(s): Tsuboi K, et al
  • Organizer: The 31st Sapporo International Cancer Symposium 2012
  • Place of Presentation: Sapporo,Japan
• [Presentation] Conformal proton irradiation by multi-layer energy filter (2012)
  • Author(s): Sakae T, et al
  • Organizer: The 31st Sapporo International Cancer Symposium Advanced Radiation Therapy and Cancer Research
  • Place of Presentation: Sapporo,Japan
• [Presentation] A Japanese- German project : Research and Development in BNCT and charged particle Therapy (2012)
  • Author(s): Sauerwein W.A.G, et al
  • Organizer: PTCOG51
  • Place of Presentation: Coex, Seoul,Korea
• [Presentation] Association between life prognosis and pretreatment liver function of proton beam therapy for the patients with HCC (2012)
  • Author(s): Mizumoto M, et al
  • Organizer: ESTRO31
  • Place of Presentation: Barcelona,Spain
• [Presentation] Preliminary clinical results of proton beam therapy for advanced neuroblastoma (2012)
  • Author(s): Oshiro Y, et al
  • Organizer: ESTRO 31
  • Place of Presentation: Barcelona,Spain
• [Presentation] Reirradiation for recurrent malignant brain tumor with X-ray radiotherapy or proton beam therapy (2012)
  • Author(s): Tsuboi K, et al
  • Organizer: ESTRO 31
  • Place of Presentation: Barcelona,Spain
• [Presentation] Association between life prognosis and pretreatment liver function of proton beam therapy for the patients with HCC (2012)
  • Author(s): Mizumoto M, Okumura T, Hashimoto T,et al
  • Organizer: ESTRO31
  • Place of Presentation: Barcelona, Spain
• [Presentation] Dose-volume histogram comparison of the lung between proton and X-ray therapy for lung cancer (2012)
  • Author(s): Ohno T, Mizumoto M, Ohshiro Y, et al
  • Organizer: PTCOG51
  • Place of Presentation: Seoul, Korea
• [Presentation] Proton beam therapy for cancer treatment at University of Tsukuba
  • Author(s): Sakurai H
  • Organizer: The 2nd Symposium of Gunma University Leading PhD Program/Gunma University Global Leader Training Program for Heavy Ion Medcine and Engineering
  • Place of Presentation: Maebashi, Gunma
  • Invited
• [Presentation] 小児固形がんに対する陽子線治療
  • Author(s): 櫻井英幸, 水本斉志, 大城佳子,ほか
  • Organizer: 第54回日本小児血液・がん学会学術集会
  • Place of Presentation: 横浜
  • Invited
• [Presentation] 陽子線治療の立場からみた癌治療増感研究
  • Author(s): 櫻井英幸, 奥村敏之, 石川仁,ほか
  • Organizer: 第15回癌治療増感研究シンポジウム
  • Place of Presentation: 奈良
• [Book] Chapter13 Proton therapy for thoracoabdominal tumors.U.Linz,ed, Ion Beam Therapy, Heidelberg, Springer-Verlag Berlin Heidelberg 2012 (2012)
  • Author(s): Sakurai H, Okumura T, Sugahara S, Nakayama H, Tokuuye K
  • Total Pages: 729
• [Book] 総論第4章E陽子線,総論第5章E陽子線,Textbook of Radiosurgery放射線外科治療の進歩(第1版)大阪(井上洋編) (2012)
  • Author(s): 磯辺智範,榮武二,櫻井英幸
  • Total Pages: 250
  • Publisher: 日本放射線外科学会/MCメディカ出版
• [Book] 各論7章腹部(26)肝臓,Textbook of Radiosurgery放射線外科治療の進歩(第1版)大阪(井上洋編) (2012)
  • Author(s): 橋本孝之,櫻井英幸
  • Total Pages: 250
  • Publisher: 日本放射線外科学会/MCメディカ出版
• [Book] 総論6章放射外科治療の注意事項,組織の耐用線量,合併症とその管理,Textbook of Radiosurgery放射線外科治療の進歩(第1版)大阪(井上洋編) (2012)
  • Author(s): 櫻井英幸,井上洋
  • Total Pages: 250
  • Publisher: 日本放射線外科学会/MCメディカ出版
• [Remarks]
  • URL: http://www.pmrc.tsukuba.ac.jp/
• [Remarks]
  • URL: http://www3.pmrc.tsukuba.ac.jp/