Development of contrast agent of ultrasonography for visualizing pancreatic islets

• Project/Area Number: 24659582
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Single-year Grants
• Research Field: General surgery
• Research Institution: Tohoku University
• Principal Investigator: SAKATA Naoaki 東北大学, 大学病院, 助教 (50431565)
• Co-Investigator(Kenkyū-buntansha): KODAMA Tetsuya 東北大学, 医工学研究科, 教授 (40271986)
• Project Period (FY): 2012-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 超音波検査 / ナノバブル / 膵島移植 / 超音波 / マイクロバブル

Research Abstract

In this study, we attempted to develop a novel contrast agent of ultrasonography aiming to visualizing transplanted pancreatic islets. The contrast agent was made by attachment of octreotide on liposome via polyethylene glycol chain, and was used after infusion of C3F8 gas. Enhanced ultrasonography using this agent for diabetic transplanted syngenetic islets showed increase of echogenicity in transplanted islets. The enhancement was significantly correlated with endocrine function of the mice.

Research Products

• [Journal Article] Strategy for clinical setting in intramuscular and subcutaneous islet transplantation (2014)
  • Author(s): Sakata N, Aoki T, Yoshimatsu G, Tsuchiya H, Hata T, Katayose Y, Egawa S, Unno M
  • Journal Title: Diabetes Metab Res Rev Volume: 30(1) Pages: 1-10
  • Peer Reviewed
• [Journal Article] Strategy for clinical setting in intramuscular and subcutaneous islet transplantation. (2014)
  • Author(s): Sakata N, Aoki T, Yoshimatsu G, Tsuchiya H, Hata T, Katayose Y, Egawa S, Unno M.
  • Journal Title: Diabetes Metab Res Rev Volume: 30 Issue: 1 Pages: 1-10
  • DOI: 10.1002/dmrr.2463
  • Peer Reviewed
• [Journal Article] Clinical experiences in the treatment of pancreatic arteriovenous malformation by total pancreatectomy with islet autotransplantation (2013)
  • Author(s): Sakata N, Goto M, Motoi F, Hayashi H, Nakagawa K, Mizuma M, Yamaya H, Hasegawa Y, Yamaguchi S, Sawada S, Ottomo S, Okada T, Fukase K, Yoshida H, Ito T, Hirota M, Ishigaki Y, Sekiguchi S, Rikiyama T, Katayose Y, Fujimori K, Egawa S, Shimosegawa T, Katagiri H, Satomi S, Unno M
  • Journal Title: Transplantation Volume: 96(5)
  • Peer Reviewed
• [Journal Article] Postoperative cholestasis and cholangitis after total pancreatectomy with biliary reconstruction impair the function of autotransplanted islets (2013)
  • Author(s): Hata T, Sakata N, Aoki T, Yoshimatsu G, Tsuchiya H, Hayashi H, Motoi F, Goto M, Katayose Y, Egawa S, Unno M
  • Journal Title: Transplantation Volume: 96(5)
  • Peer Reviewed
• [Journal Article] Imaging of transplanted islets by positron emission tomography, magnetic resonance imaging, and ultrasonography (2013)
  • Author(s): Sakata N, Yoshimatsu G, Tsuchiya H, Aoki T, Mizuma M, Motoi F, Katayose Y, Kodama T, Egawa S, Unno M
  • Journal Title: Islets Volume: 5(5) Pages: 179-187
  • Peer Reviewed
• [Journal Article] Development of polyvinyl alcohol bioartificial pancreas with rat islets and mesenchymal stem cells (2013)
  • Author(s): Yoshimatsu G, Sakata N, Tsuchiya H, Ishida M, Motoi F, Egawa S, Sumi S, Goto M, Unno M
  • Journal Title: Transplant Proc Volume: 45(5) Pages: 1875-80
  • Peer Reviewed
• [Journal Article] Clinical Experiences in the Treatment of Pancreatic Arteriovenous Malformation by Total Pancreatectomy With Islet Autotransplantation. (2013)
  • Author(s): Sakata N, Goto M, Motoi F, Hayashi H, Nakagawa K, Mizuma M, Yamaya H, Hasegawa Y, Yamaguchi S, Sawada S, Ottomo S, Okada T, Fukase K, Yoshida H, Ito T, Hirota M, Ishigaki Y, Sekiguchi S, Rikiyama T, Katayose Y, Fujimori K, Egawa S, Shimosegawa T, Katagiri H, Satomi S, Unno M
  • Journal Title: Transplantation Volume: 96(5) Issue: 5 Pages: e38-e40
  • DOI: 10.1097/tp.0b013e3182a01333
  • Peer Reviewed
• [Journal Article] Postoperative Cholestasis and Cholangitis after Total Pancreatectomy with Biliary Reconstruction Impair the Function of Autotransplanted islets (2013)
  • Author(s): Hata T, Sakata N, Aoki T, Y oshimatsu G, T suchiya H, Hayashi H, Motoi F, Goto M, Katayose Y, Egawa S, Unno M
  • Journal Title: Transplantation Volume: 96(5) Issue: 5 Pages: e40-e43
  • DOI: 10.1097/tp.0b013e3182a049bb
  • Peer Reviewed
• [Journal Article] Imaging of transplanted islets by positron emission tomography, magnetic resonance imaging, and ultrasonography. (2013)
  • Author(s): Sakata N, Yoshimatsu G, Tsuchiya H, Aoki T, Mizuma M, Motoi F, Katayose Y, Kodama T, Egawa S, Unno M.
  • Journal Title: Islets Volume: 5 Pages: 179-187
  • Peer Reviewed
• [Journal Article] Development of polyvinyl alcohol bioartificial pancreas with rat islets and mesenchymal stem cells. (2013)
  • Author(s): Yoshimatsu G, Sakata N, Tsuchiya H, Ishida M, Motoi F, Egawa S, Sumi S, Goto M, Unno M
  • Journal Title: Transplant Proc Volume: 45 Issue: 5 Pages: 1875-80
  • DOI: 10.1016/j.transproceed.2013.01.043
  • Peer Reviewed
• [Journal Article] Intraoperative ultrasound examination is useful for monitoring transplanted islets : a case report (2012)
  • Author(s): Sakata N, Goto M, Gumpei Y, Mizuma M, Motoi F, Satomi S, Unno M
  • Journal Title: Islets Volume: 4(5) Pages: 339-42
  • Peer Reviewed
• [Journal Article] Animal models ofdiabetes mellitus for islet transplantation. (2012)
  • Author(s): Sakata N, Yoshimatsu G, Tsuchiya H, Egawa S, Unno M.
  • Journal Title: Exp Diabetes Res Volume: 256707 Pages: 256707-256707
  • DOI: 10.1155/2012/256707
  • Peer Reviewed
• [Journal Article] Intraoperative ultrasound examination is useful for monitoring transplanted islets (2012)
  • Author(s): Sakata N, Goto M, Gumpei Y, Mizuma M, Motoi F, Satomi S, Unno M
  • Journal Title: Islets Volume: 4(5) Issue: 5 Pages: 1-4
  • DOI: 10.4161/isl.22384
  • Peer Reviewed
• [Presentation] Clinical Experiences of Islet Autotransplantation in Tohoku University (2014)
  • Author(s): 坂田直昭、後藤昌史、元井冬彦、片寄友、江川新一、下瀬川徹、里見進、海野倫明
  • Organizer: 第45回日本膵臓学会大会
  • Place of Presentation: 北九州
• [Presentation] 筋肉内膵島移植の臨床応用に向けて (2014)
  • Author(s): 坂田直昭、吉松軍平、土屋朗之、畠達夫、深瀬正彦、元井冬彦、内藤剛、片寄友、江川新一、海野倫明
  • Organizer: 第69回日本消化器外科学会総会
  • Place of Presentation: 郡山
• [Presentation] 膵島移植における神経成長因子(Nerve Growth Factor)の役割と機能解析 (2014)
  • Author(s): 畠達夫、坂田直昭、吉松軍平、土屋朗之、深瀬正彦、青木豪、川口桂、薮内伸一、深瀬耕二、水間正道、中川圭、林洋毅、岡田恭穂、森川孝則、吉田寛、元井冬彦、内藤剛、片寄友、江川新一、海野倫明
  • Organizer: 第114回日本外科学会定期学術集会
  • Place of Presentation: 京都
• [Presentation] Co-transplantation with bone marrow derived MSCs in the intramuscular islet transplantation (2014)
  • Author(s): Yoshimatsu G, Sakata N, Tsuchiya H, Fukase M, Hata T, Katayose Y, Egawa S, Unno M
  • Organizer: International Hepato-Pancreato-Biliary Association 2014 11^<th> World Congress
  • Place of Presentation: Seoul, Korea
• [Presentation] 自家膵島移植とその検討 (2014)
  • Author(s): 坂田直昭、後藤昌史、吉松軍平、畠達夫、林洋毅、中川圭、山谷英之、澤田正二郎、廣田衛久、元井冬彦、江川新一、片桐秀樹、下瀬川徹、里見進、海野倫明
  • Organizer: 第41回膵・膵島移植研究会
  • Place of Presentation: 名古屋
• [Presentation] マウスモデルにおける筋肉内膵島移植に対する骨髄由来間葉系幹細胞共移植の効果 (2014)
  • Author(s): 吉松軍平、坂田直昭、土屋朗之、畠達夫、深瀬正彦、青木豪、森田浩美、竹村太郎、箕輪貴司、元井冬彦、片寄友、江川新一、海野倫明
  • Organizer: 第41回膵・膵島移植研究会
  • Place of Presentation: 名古屋
• [Presentation] 自家膵島移植の経験とその検討 (2014)
  • Author(s): 坂田直昭、後藤昌史，吉松軍平，畠 達夫，林 洋毅，中川 圭，山谷英之，澤田正二郎，廣田衛久，元井冬彦，江川新一，片桐秀樹，下瀬川徹，里見 進，海野倫明
  • Organizer: 第41回日本膵・膵島移植研究会
  • Place of Presentation: 名古屋
• [Presentation] 自家膵島移植後3年の膵動静脈奇形の1例 (2014)
  • Author(s): 坂田直昭、後藤昌史，元井冬彦，林 洋毅，山谷英之，吉松軍平，畠 達夫，関口 悟，片寄 友，江川新一，里見 進，海野倫明
  • Organizer: 第1回日本臨床外科学会宮城県支部総会
  • Place of Presentation: 仙台
• [Presentation] Co-transplantation with bone marrow derived MSCs in the intramuscular islet transplantation (2014)
  • Author(s): Yoshimatsu G, Sakata N, Tsuchiya H, Fukase M, Hata T, Katayose Y, Egawa S, Unno M
  • Organizer: International Hepatp-Pancreato-Biliary Association 2014 11th World Congress
  • Place of Presentation: Seoul, Korea
• [Presentation] マウスモデルにおける筋肉内膵島移植に対する骨髄由来間葉系幹細胞共移植の効果 (2014)
  • Author(s): 吉松軍平、坂田直昭，土屋朗之，畠 達夫，深瀬正彦，青木 豪，森田浩美，竹村太郎，箕輪貴司，元井冬彦，片寄 友，江川新一，海野倫明
  • Organizer: 第41回日本膵・膵島移植研究会
  • Place of Presentation: 名古屋
• [Presentation] 細胞外基質が膵島に与える有効性の検討 (2014)
  • Author(s): 土屋朗之 坂田直昭 吉松軍平 畠 達夫 深瀬正彦 青木 豪 岡田恭穂 中川 圭 森川孝則 吉田 寛 元井冬彦 内藤 剛 片寄 友 江川新一 海野倫明
  • Organizer: 第41回日本膵・膵島移植研究会
  • Place of Presentation: 名古屋
• [Presentation] 神経成長因子(Nerve Growth Factor)が膵島に与える影響と膵島移植の効率化についての検討 (2014)
  • Author(s): 畠 達夫、坂田直昭，吉松軍平，土屋朗之，深瀬正彦，青木 豪，岡田恭穂，中川 圭，森川孝則，吉田 寛，元井冬彦，内藤 剛，片寄 友，江川新一，海野倫明
  • Organizer: 第41回日本膵・膵島移植研究会
  • Place of Presentation: 名古屋
• [Presentation] 当科における慢性膵炎に対する取り組み (2013)
  • Author(s): 坂田直昭、元井冬彦、吉田寛、内藤剛、三浦康、廣田衛久、正宗淳、片寄友、江川新一、下瀬川徹、海野倫明
  • Organizer: 第194回日本消化器病学会東北支部例会
  • Place of Presentation: 仙台
  • Year and Date: 2013-02-09
• [Presentation] Imaging of transplanted islets by ultrasonography (2013)
  • Author(s): Sakata N, Yoshimatsu G, Tsuchiya H, Aoki T, Mizuma M, Motoi F, Katayose Y, Kodama T, Unno M
  • Organizer: The 14 World Congress of the International Pancreas and Islet Transplant Association (IPITA2013)
  • Place of Presentation: Monterey, USA
• [Presentation] Intramuscular co-transplantation of islets and bone marrow derived mesenchymal stem cells in rodent model (2013)
  • Author(s): Yoshimatsu G, Sakata N, Tsuchiya H, Hata T, Fukase M, Motoi F, Katayose Y, Egawa S, Unno M
  • Organizer: The 14^<th> World Congress of the International Pancreas and Islet Transplant Association (IPITA2013)
  • Place of Presentation: Monterey, USA
• [Presentation] Transplant efficacy : understanding the effectiveness of islet transplantation (2013)
  • Author(s): Tsuchiya H, Sakata N, Yoshimatsu G, Unno M
  • Organizer: The 14^<th> World Congress of the International Pancreas and Islet Transplant Association (IPITA2013)
  • Place of Presentation: Monterey, USA
• [Presentation] Postoperative cholangitis and liver dysfunction after total pancreatectomy with biliary reconstruction impair the function of autotransplanted islets (2013)
  • Author(s): Hata T, Sakata N, Aoki T, Yoshimatsu G, Tsuchiya H, Hayashi H, Motoi F, Goto M, Katayose Y, Egawa S, Unno M
  • Organizer: The 14^<th> World Congress of the International Pancreas and Islet Transplant Association (IPITA2013)
  • Place of Presentation: Monterey, USA
• [Presentation] 膵島移植の成績向上を目指して : 当研究グループの取り組み (2013)
  • Author(s): 坂田直昭、吉松軍平、土屋朗之、畠達夫、青木豪、水間正道、中川圭、林洋毅、元井冬彦、内藤剛、片寄友、海野倫明
  • Organizer: 第49回日本移植学会総会
  • Place of Presentation: 京都
• [Presentation] Efficacy of intramuscular islet transplantation (2013)
  • Author(s): Tsuchiya H, Sakata N, Yoshimatsu G, Unno M
  • Organizer: The 13^<th> Congress of the Asian Society of Transplantation (CAST2013)
  • Place of Presentation: Kyoto
• [Presentation] Bone Marrow and Mesenchymal Stem Cell Transplantation for Islet Transplantation (2013)
  • Author(s): Sakata N, Yoshimatsu G, Tsuchiya H, Fukase M, Hata T, Unno M
  • Organizer: ASahct2013
  • Place of Presentation: Sendai
• [Presentation] 門脈内膵島移植の問題と新たな移植部位の確立に向けて (2013)
  • Author(s): 坂田直昭、吉松軍平、土屋朗之、青木豪、川口桂、薮内伸一、深瀬耕二、大塚英郎、乙供茂、水間正道、岡田恭穂、中川圭、林洋毅、森川孝則、吉田寛、元井冬彦、内藤剛、片寄友、江川新一、海野倫明
  • Organizer: 第44回日本膵臓総会
  • Place of Presentation: 仙台
• [Presentation] 間葉系幹細胞破水等移植成績を向上させる光となるか (2013)
  • Author(s): 坂田直昭、吉松軍平、土屋朗之、畠達夫、深瀬正彦、青木豪、石田晶玄、元井冬彦、片寄友、海野倫明
  • Organizer: 第68回日本消化器外科学会総会
  • Place of Presentation: 宮崎
• [Presentation] 移植膵島の超音波画像 (2013)
  • Author(s): 坂田直昭、後藤昌史、小玉哲也、元井冬彦、水間正道、吉松軍平、青木豪、深瀬耕二、大塚英郎、乙供茂、岡田恭穂、中川圭、林洋毅、森川孝則、吉田寛、内藤剛、三浦康、片寄友、里見進、海野倫明
  • Organizer: 第113回日本外科学会定期学術集会
  • Place of Presentation: 福岡
• [Presentation] ドナー膵の機能評価を予見するためのCT所見に関する検討 (2013)
  • Author(s): 坂田直昭、江川新一、力山敏樹、吉松軍平、元井冬彦、三浦康、片寄友、海野倫明
  • Organizer: 第40回日本膵・膵島移植研究会
  • Place of Presentation: 高松
• [Presentation] 本邦における自家膵島移植の適応に関する検討 (2013)
  • Author(s): 坂田直昭、吉松軍平、海野倫明
  • Organizer: 第40回日本膵・膵島移植研究会
  • Place of Presentation: 高松
• [Presentation] 海外留学の魅力と必要性についての私見 (2013)
  • Author(s): 坂田直昭、海野倫明
  • Organizer: 第75回日本臨床外科学会総会
  • Place of Presentation: 名古屋
• [Presentation] 膵島移植の成績向上を目指して：当研究グループの取り組み (2013)
  • Author(s): 坂田直昭、吉松軍平，土屋朗之，畠 達夫，青木 豪，水間正道，中川 圭，林 洋毅，元井冬彦，内藤 剛，片寄 友，海野倫明
  • Organizer: 第49回日本移植学会総会
  • Place of Presentation: 京都
• [Presentation] 門脈内膵島移植の問題と新たな移植部位の確立に向けて (2013)
  • Author(s): 坂田直昭、吉松軍平，土屋朗之，青木 豪，川口 桂，藪内伸一，深瀬耕二，大塚英郎，乙供 茂，水間正道，岡田恭穂，中川 圭，林 洋毅，森川孝則，吉田 寛，元井冬彦，内藤 剛，片寄 友，江川新一，海野倫明
  • Organizer: 第44回日本膵臓学会大会
  • Place of Presentation: 仙台
• [Presentation] 間葉系幹細胞は膵島移植成績を向上させる光となるか (2013)
  • Author(s): 坂田直昭、吉松軍平，土屋朗之，畠 達夫，深瀬正彦，青木 豪，石田晶玄，元井冬彦，片寄 友，海野倫明
  • Organizer: 第68回日本消化器外科学会総会
  • Place of Presentation: 宮崎
• [Presentation] Imaging examination for islet transplantation (2013)
  • Author(s): Sakata N, Yoshimatsu G, Tsuchiya H, Hata T, Fukase M, Unno M
  • Organizer: NIH-Tohoku University-JSPS Symposium
  • Place of Presentation: Sendai
• [Presentation] Imaging of transplanted islets by ultrasonography (2013)
  • Author(s): Sakata N, Yoshimatsu G, Tsuchiya H, Aoki T, Mizuma M, Motoi F, Katayose Y, Kodama T, Unno M
  • Organizer: the 14th World Congress of the International Pancreas and Islet Transplant Association (IPITA 2013)
  • Place of Presentation: Monterey, USA
• [Presentation] Intramuscular co-transplantation of islets and bone marrow derived mesenchymal stem cells in rodent model (2013)
  • Author(s): Yoshimatsu G, Sakata N. Aoki T. Tsuchiya H. Hata T. Fukase M. Motoi F. Katayose Y. Egawa S. Unno M.
  • Organizer: the 14th World Congress of the International Pancreas and Islet Transplant Association (IPITA 2013)
  • Place of Presentation: Monterey, USA
• [Presentation] 膵島移植における筋肉内移植の有効性の検討 (2013)
  • Author(s): 土屋朗之、坂田直昭,吉松軍平,海野倫明
  • Organizer: 第49回日本移植学会総会
  • Place of Presentation: 名古屋
• [Presentation] 移植効率を評価するパラメータの検討 (2013)
  • Author(s): 土屋朗之、坂田直昭,吉松軍平,畠達夫,深瀬正彦,青木 豪,片寄 友,江川新一,海野倫明
  • Organizer: 第68回日本消化器外科学会総会
  • Place of Presentation: 宮崎
• [Presentation] 膵島移植における安全かつ有効な移植部位の検討 (2013)
  • Author(s): 土屋朗之、坂田直昭,吉松軍平,青木豪,水間正道,深瀬耕二,乙供 茂,大塚英郎,森川孝則,林 洋毅,中川 圭 ,岡田恭穂,吉田 寛,元井冬彦,内藤 剛,三浦 康,片寄 友,柴田 近,海野倫明
  • Organizer: 第113回日本外科学会定期学術集会
  • Place of Presentation: 福岡
• [Presentation] Efficacy of intramuscular islet transplantation (2013)
  • Author(s): Tsuchiya H, Sakata N, Yoshimatsu G, Unno M
  • Organizer: the 13th Congress of the Asian Society of Transplantation (CAST2013)
  • Place of Presentation: Kyoto
• [Presentation] Transplant efficacy: understanding the effectiveness of islet transplantation. (2013)
  • Author(s): Tsuchiya H, Sakata N, Yoshimatsu G, Unno M
  • Organizer: the 14th World Congress of the International Pancreas and Islet Transplant Association (IPITA 2013)
  • Place of Presentation: Monterey, USA
• [Presentation] Postoperative cholangitis and liver dysfunction after total pancreatectomy with biliary reconstruction impair the function of autotransplanted islets (2013)
  • Author(s): Hata T, Sakata N, Aoki T, Yoshimatsu G, Tsuchiya H, Hayashi H, Motoi F, Goto M, Katayose Y, Egawa S, Unno M
  • Organizer: the 14th World Congress of the International Pancreas and Islet Transplant Association (IPITA 2013)
  • Place of Presentation: Monterey, USA
• [Presentation] 膵全摘後脂肪肝の危険因子についての検討 (2013)
  • Author(s): 畠 達夫、坂田直昭，石田晶玄，青木 豪，岡田恭穂，水間正道，中川 圭，乙供 茂，森川孝則，吉田 寛，元井冬彦，内藤 剛，片寄 友，江川新一，海野倫明
  • Organizer: 第75回日本臨床外科学会総会
  • Place of Presentation: 名古屋
• [Presentation] ドナー膵の機能評価を予見するためのCT所見に関する検討. (2013)
  • Author(s): 坂田直昭，江川新一，力山敏樹，吉松軍平，元井冬彦，三浦 康，片寄 友，海野倫明
  • Organizer: 第40回日本膵・膵島移植研究会
  • Place of Presentation: 高松
• [Presentation] Surgical treatment for chronic pancreatitis, discussion of drainage and total pancreatectomy with islet autotransplantation (2012)
  • Author(s): Sakata N, Yoshimatsu G, Aoki T, Ishida M, Fukase K, Ottomo S, Mizuma M, Okada T, Nakagawa K, Hayashi H, Morikawa T, Yoshida H, Motoi F, Naitoh T, Katayose Y, Miura K, Egawa S, Unno M
  • Organizer: 2012 Joint American Pancreatic Association (APA) / International Association of Pancreatology (IAP) Annual Meeting
  • Place of Presentation: Miami, USA
• [Presentation] Intraoperative ultrasound examination is useful for monitoring transplanted islets (2012)
  • Author(s): Sakata N, Goto M, Yoshimatsu G, Mizuma M, Motoi F, Satomi S, Unno M
  • Organizer: XXIV International Cogress of The Transplantation Society
  • Place of Presentation: Berlin, Germany
• [Presentation] 慢性膵炎の外科的治療に関する検討 (2012)
  • Author(s): 坂田直昭，吉松軍平, 青木 豪， 石田昌玄, 吉田 寛, 元井冬彦, 内藤 剛, 片寄 友, 三浦 康, 海野倫明
  • Organizer: 第48回日本移植学会総会
  • Place of Presentation: 名古屋
• [Presentation] 膵動静脈奇形に対する新たな治療戦略 (2012)
  • Author(s): 坂田直昭，後藤昌史, 元井冬彦, 林 洋毅, 中川 圭, 水間正道, 山谷英之, 長谷川豊, 澤田正二郎, 吉松軍平, 伊藤経夫, 菅野 敦, 廣田衛久, 石垣 泰, 力山敏樹, 江川新一,他
  • Organizer: JDDW2012
  • Place of Presentation: 神戸
• [Presentation] Surgical treatment for chronic pancreatitis, discussion of drainage and total pancreatectomy with islet autotransplantation. (2012)
  • Author(s): Sakata N, Yoshimatsu G, Aoki T, Ishida M, Fukase K, Ottomo S, Mizuma M, Okada T, Nakagawa K, Hayashi H, Morikawa T, Yoshida H, Motoi F, Naitoh T, Katayose Y, Miura K, Egawa S, Unno M
  • Organizer: 2012 Joint American Pancreatic Association (APA) / International Association of Pancreatology (IAP) Annual Meeting
  • Place of Presentation: Miami, USA
• [Presentation] Intraoperative ultrasound examination is useful for monitoring transplanted islets. (2012)
  • Author(s): Sakata N, Goto M, Yoshimatsu G, Mizuma M, Motoi F, Satomi S, Unno M
  • Organizer: XXIV International Cogress of The Transplantation Society
  • Place of Presentation: Berlin, Germany
• [Remarks] ReaD & Researchship
  • URL: http://researchmap.jp/read0154889/
• [Remarks] Researchmap
  • URL: http://researchmap.jp/read0154889/
• [Remarks] ReaD & Researchship
  • URL: http://researchmap.jp/read0154889/
• [Patent(Industrial Property Rights)] 膵外分泌機能不全のモデル動物 (2012)
  • Inventor(s): 海野倫明、坂田直昭、石田晶玄、吉松軍平
  • Industrial Property Rights Holder: 海野倫明、坂田直昭、石田晶玄、吉松軍平
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2012-238416
  • Filing Date: 2012-10-29