| Project/Area Number |
24659638
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | Yokohama City University |
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Principal Investigator |
NOISHIKI Yasuharu 横浜市立大学, 医学(系)研究科(研究院), 客員教授 (60033263)
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| Co-Investigator(Renkei-kenkyūsha) |
ITO Hiroshi 横浜市立大学, 医学研究科, 客員教授 (80124303)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | ステントグラフト / 触れ / 熱融着 / ポリエステル繊維 / 崇高 / 芯鞘構造 / 細径化 / 縫合糸 / ポリエステル |
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| Research Abstract |
Stent grafts have several problems which should be solved urgently. One of them is a fraying problem after suture ligation. Expandable metal wires are fixed by sutures with fabric grafts by sutures, which are made of polymer materials such as polyester fibers. As polymer materials are usually slippery, more than three-time ligations are required to prevent the knots become loose, which resulted in bulky. Generally bulky knots are not desirable for slim stent grafts. In order to solve the problem, we have developed a hybrid suture made of regular polyester fibers coated with special polymer having a lower melting point, around 180~220 Celsius,while regular polyester fibers melts at 260 Celsius. Using our special sutures, all the knots of ligated sites of the tested stent graft were fixed by meltdown of the polymer when the graft was heated at 220 Celsius. Consequently, the fraying problem is completely overcome after 220 Celsius heating of stent grafts.
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