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A study searching for pain-associated biomarkers

Research Project

Project/Area Number 24659702
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Anesthesiology/Resuscitation studies
Research InstitutionNagoya City University

Principal Investigator

TAKESHI Sugiura  名古屋市立大学, 医学(系)研究科(研究院), 講師 (20295611)

Co-Investigator(Kenkyū-buntansha) SOBUE Kazuya  名古屋市立大学, 大学院医学研究科, 教授 (90264738)
ASAI Kiyofumi  名古屋市立大学, 大学院医学研究科, 教授 (70212462)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsバイオマーカー / 痛み病態モデル / 疼痛病態モデル
Outline of Final Research Achievements

The Aim of this study is to identify the specific biomarker for neuropathic pain, as for diagnosis of neuropathic pain and evaluation of therapeutic efficacy. We confirmed the hyperalgesia-like behavior in the pain animal model. The use of cerebrospinal fluid as a sample to measure the biomarker is more challenging than spinal, peripheral nerve and blood. We could have not identified the appropriate protein to analyze for biomarker of neuropathic pain due to technical difficulties for adjustment of materials.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (4 results)

All 2015 2014

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (3 results) (of which Invited: 1 results)

  • [Journal Article] カルバマゼピン内服治療中に重度低ナトリウム血症をきたした顔面帯状疱疹痛の1症例2014

    • Author(s)
      浅井明倫、杉浦健之、徐 民恵、平手博之、藤田義人、祖父江和哉
    • Journal Title

      日本ペインクリニック学会誌

      Volume: 21 Pages: 537-538

    • NAID

      130004697169

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 痛みの神経科学が進むべき新方向について~慢性痛治療へのヒントとなるか2015

    • Author(s)
      杉浦健之
    • Organizer
      東海・北陸ペインクリニック学会第26回東海地方会ランチョンセミナー
    • Place of Presentation
      ウインクあいち(愛知県)
    • Year and Date
      2015-05-09
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 疼痛性障害に対し集学的治療が有効であった1例2015

    • Author(s)
      浅井明倫、杉浦健之、草間宣好、森島徹朗、徐 民恵、太田晴子、加藤利奈、吉澤佐也、冨田麻衣子、薊 隆文、祖父江和哉
    • Organizer
      東海・北陸ペインクリニック学会第26回東海地方会
    • Place of Presentation
      ウインクあいち(愛知県)
    • Year and Date
      2015-05-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] 癒着性くも膜炎のため脊髄刺激療法用カテーテル型電極が挿入困難でプレート型電極が有効で会った1症例2014

    • Author(s)
      浅井明倫,薊 隆文,杉浦健之,吉澤佐也,播磨 恵,太田晴子,竹内直子,徐 民恵
    • Organizer
      日本ペインクリニック学会第48回大会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2014-07-26
    • Related Report
      2014 Annual Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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