| Project/Area Number |
24659702
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Nagoya City University |
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Principal Investigator |
TAKESHI Sugiura 名古屋市立大学, 医学(系)研究科(研究院), 講師 (20295611)
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| Co-Investigator(Kenkyū-buntansha) |
SOBUE Kazuya 名古屋市立大学, 大学院医学研究科, 教授 (90264738)
ASAI Kiyofumi 名古屋市立大学, 大学院医学研究科, 教授 (70212462)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | バイオマーカー / 痛み病態モデル / 疼痛病態モデル |
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| Outline of Final Research Achievements |
The Aim of this study is to identify the specific biomarker for neuropathic pain, as for diagnosis of neuropathic pain and evaluation of therapeutic efficacy. We confirmed the hyperalgesia-like behavior in the pain animal model. The use of cerebrospinal fluid as a sample to measure the biomarker is more challenging than spinal, peripheral nerve and blood. We could have not identified the appropriate protein to analyze for biomarker of neuropathic pain due to technical difficulties for adjustment of materials.
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