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Development of new cancer therapeutic formulation with BCG mycolic acid

Research Project

Project/Area Number 24659710
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Urology
Research InstitutionUniversity of Tsukuba

Principal Investigator

MIYAZAKI JUN  筑波大学, 医学医療系, 准教授 (10550246)

Co-Investigator(Kenkyū-buntansha) NISHIYAMA Hiroyuki  筑波大学, 医学医療系, 教授 (20324642)
TAKAOKA Eiichiro  筑波大学, 附属病院, 病院講師 (50625340)
KIMURA Tomokazu  筑波大学, 附属病院, 病院講師 (10633191)
Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsミコール酸 / ビーシージー / リポソーム / 癌免疫 / Mycobacterium bovis BCG / オクタアルギニン
Research Abstract

We have developed a mycolic acid liposomal formulation. Using subcutaneous inoculation model, we are investigating the anti-tumor effect. We are now using an orthotopic model to examine the anti-tumor effect in the future.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (3 results)

All 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Bacillus Calmette-Guerin (BCG) immunotherapy for bladder cancer: current understanding and perspectives on engineered BCG vaccine.2013

    • Author(s)
      Kawai K, Miyazaki J, Joraku A, Nishiyama H, Akaza H.
    • Journal Title

      Cancer Sci.

      Volume: 104 Issue: 1 Pages: 22-27

    • DOI

      10.1111/cas.12075

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Presentation] BCG-CWS搭載ナノ粒子を基盤とした膀胱癌治療剤の開発2013

    • Author(s)
      中村孝司、吹上雅文、中谷彰洋、矢野郁也、宮崎淳、西山博之、赤座英之、伊藤俊宏、細川裕之、中山俊憲、原島秀吉
    • Organizer
      第6回BCG注入療法研究会
    • Place of Presentation
      如水会館(東京都千代田区)
    • Year and Date
      2013-11-22
    • Related Report
      2013 Final Research Report
  • [Patent(Industrial Property Rights)] 特許2012

    • Inventor(s)
      宮崎淳
    • Industrial Property Rights Holder
      宮崎淳
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-188129
    • Filing Date
      2012-08-28
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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