the research of the mutual relationship in the mouse auditory cortex using the reversible photo- inactivation
| Project/Area Number |
24659746
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Niigata University |
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Principal Investigator |
TAKAHASHI Sugata 新潟大学, 医歯(薬)学総合研究科, 客員研究員 (10154824)
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| Co-Investigator(Kenkyū-buntansha) |
TAKAHASHI KUNIYUKI 新潟大学, 医歯学系, 准教授 (40452057)
KUBOTA YAMATO 新潟大学, 医歯学系, 助教 (40547593)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 大脳聴覚野 / マウス / イメージング / 光抑制法 / 光抑制 |
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| Outline of Final Research Achievements |
It is known that there are the functional columns in the brain with the different roles depending on the sites. A conventional study of local cortical function in animals could be only in invasive research such as electrical cauterization. We have improved our equipment to obtain the bilateral auditory cortex simultaneously and we have recorded the responses to various sounds in the mouse auditory cortex. And we have also research the relationship between bilateral auditory cortices with transcranial reversible photo-inactivation. As a result, we found the new areas which specifically respond to the frequency change direction of the frequency modulated sound, and the end of the sound in the mouse auditory cortex. We also found that the auditory responses were influenced by the inhibition of the opposite auditory cortex. We think that these results can contribute to further auditory cortex research.
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Report
(5 results)
Research Products
(7 results)
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[Presentation] The cortical area located dorsally to auditory cortex involved in sound-shape association memory in mice2015
Author(s)
Tatsuya Yamagishi , Hiroaki Tsukano , Hironori Baba, Yuusuke Honma , Shinsuke Ohshima, Yamato Kubota, Kuniyuki Takahashi, Ryuichi Hishida, Takeshi Yagi, Katsuei Shibuki , Sugata Takahashi
Organizer
The 30th Politzer Society Meeting / the 1st World Congress of Otology
Place of Presentation
朱鷺メッセ（新潟県、新潟市）
Year and Date
2015-06-30
Related Report
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