| Project/Area Number |
24659751
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
OMORI KOICHI 福島県立医科大学, 医学部, 教授 (10233272)
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| Co-Investigator(Renkei-kenkyūsha) |
NAKAMURA Tatsuo 京都大学, 再生医科学研究所, 准教授 (70227908)
WADA Ikuo 福島県立医科大学, 医学部, 教授 (40182969)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | iPS細胞 / 再生医学 / 気管上皮 / 再生 |
|---|
| Research Abstract |
The purpose of this study is to establish a technique to differentiate mouse induced pluripotent stem (iPS) cells to respiratory epithelial tissue and to regenerate tracheal tissue. The presence of respiratory epithelium-like tissue was observed after several days culture by hematoxylin eosin staining and immunohistochemistry. This is the first study to demonstrate the potential of iPS cells for regeneration of the respiratory epithelium.
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