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Development of the new skin grafting method (micro cube skin grafting) which has a high wound healing effect.

Research Project

Project/Area Number 24659778
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Plastic surgery
Research InstitutionHirosaki University

Principal Investigator

Urushidate Satoshi  弘前大学, 医学(系)研究科(研究院), 教授 (80321967)

Co-Investigator(Kenkyū-buntansha) YOKOI Katsunori  弘前大学, 大学院医学研究科, 講師 (00271809)
MIKAMI Makoto  弘前大学, 大学院医学研究科, 助教 (30396402)
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords組織移植 / 創傷治癒 / 熱傷 / 皮膚移植 / 皮膚潰瘍 / 皮膚移植術
Outline of Final Research Achievements

The micro cube skin grafting is a new skin grafting method that minced small cube skins are grafted on the skin ulcer. The utility of this method was investigated using skin ulcers of rats, and we have revealed whether this method had the better wound healing effects compared to the traditional methods. The grafted skins using this method were well survived under the moist environment in spite of the direction of the skin. The epithelialization was observed not only from the edge of the epithelium but also from the cutaneous appendixes. After four weeks, the epithelialized area from the grafted skin spread to 28~113 times of the original size. In conclusion, it was considered that the micro cube skin grafting is a useful method for the treatment of severe burns.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report

Research Products

(2 results)

All 2014 Other

All Presentation (2 results)

  • [Presentation] 対面積効果の高い皮膚移植法の開発~第一報~2014

    • Author(s)
      三上 誠、樋熊有子、齊藤真喜子、和田尚子、齋藤百合子、渡辺庸介、横井克憲、漆舘聡志
    • Organizer
      第23回日本形成外科学会基礎学術集会
    • Place of Presentation
      松本市
    • Year and Date
      2014-10-09 – 2014-10-10
    • Related Report
      2014 Research-status Report
  • [Presentation] 対面積効果の高い皮膚移植法の開発

    • Author(s)
      三上誠、和田尚子、齋藤百合子、齊藤真喜子、樋熊有子、渡辺庸介、横井克憲、漆舘聡志
    • Organizer
      第9回札弘形成外科研究会
    • Place of Presentation
      函館市
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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