• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of In vivo tissue engineered autologous tube grafts "Biotubes" for suturess microvascular reconstruction

Research Project

Project/Area Number 24659786
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Plastic surgery
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

WATANABE Taiji  京都府立医科大学, 医学(系)研究科(研究院), 助教 (20448723)

Co-Investigator(Kenkyū-buntansha) OHBA Kenkichi  関西大学, 付属研究所, 研究員 (30029186)
NAKAYAMA Yasuhide  独立行政法人国立循環器病研究センター, 生体医工学部, 室長 (50250262)
KANDA Keiichi  京都府立医科大学, 医学(系)研究科(研究院), 講師 (60295649)
TAJIKAWA Tsutomu  関西大学, 工学部, 准教授 (80351500)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsbiotube / 生体内組織形成技術 / 小口径代用血管 / バイオチューブ
Outline of Final Research Achievements

In this study, we aim to develop the sutureless biotube as application of the complete autologous connective tissue small diameter vascular graft" biotube" which are constructed by "in body tissue architecture" technology under the novel concept of the D.I.Y. regenerative medicine. By using this sutureless biotube, we can reconstruct any small caliber vessels such as artery, vein, lymphatics without anastomosing. In this study period, we succeeded to integrate biotubes and native vesssels without anastomosing.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (12 results)

All 2014 2013 2012

All Presentation (12 results)

  • [Presentation] 体内で作製した結合組織膜(Biosheet)は修復材料としての自己心膜の代用になり得る2014

    • Author(s)
      山南 将志、渡辺 太治他
    • Organizer
      第67回日本胸部外科学会定期学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2014-09-30 – 2014-10-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] Autologous connective tissue membrane(bio-sheet) as a substitute for self-pericardium2014

    • Author(s)
      T.Watanabe et al.
    • Organizer
      XLI Annual ESAO(European Society for Artificial Organs) Congress
    • Place of Presentation
      Roma, Italy
    • Year and Date
      2014-09-17 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Long term auto implantation of autologous tissue small caliber vascular grafts(biotubes)2014

    • Author(s)
      M.Yamanami. T.Watanabe. et al.
    • Organizer
      XLI Annual ESAO(European Society for Artificial Organs) Congress
    • Place of Presentation
      Roma, Italy
    • Year and Date
      2014-09-17 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Development of In vivo Tissue-Engineered Cardiovascular Prosthesis2014

    • Author(s)
      K.Kanda. T.Watanabe. et al.
    • Organizer
      63th European society for Cardiovascular and Endovascular Surgery
    • Place of Presentation
      Nice, France
    • Year and Date
      2014-04-24 – 2014-04-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] Long-term results of autologous tissue extremely small-caliber vascular grafts(biotubes) in a rat abdominal aorta replacement model2014

    • Author(s)
      M.Yamanami. T.Watanabe. et al.
    • Organizer
      63th European society for Cardiovascular and Endovascular Surgery
    • Place of Presentation
      Nice, France
    • Year and Date
      2014-04-24 – 2014-04-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] バイオチューブ人工血管移植後6年目の超音波による開存性、形態的変化の評価2013

    • Author(s)
      渡辺太治、山南将志、水野壮司、神田圭一、夜久均、中山泰秀
    • Organizer
      第51回日本人工臓器学会大会
    • Place of Presentation
      神奈川県横浜市
    • Related Report
      2013 Research-status Report
  • [Presentation] Long term patency and durability of in vivo tissue engineered autologous tube grafts "Biotubes".2013

    • Author(s)
      T Watanabe, K Kanda, M Yamanami, O Sakai, H Yaku, Y Nakayama.
    • Organizer
      62nd ESCVS (the European Society for Cardiovascular and Endovascular Surgery)
    • Place of Presentation
      レーゲンスブルグ ドイツ
    • Related Report
      2013 Research-status Report
  • [Presentation] Follow-up report on the biotube of 5-year implantation-angiographic and sonographic evaluations.2013

    • Author(s)
      T Watanabe, K Kanda, T Mizuno, Y Nakayama, H Yaku, M Yamanami.
    • Organizer
      XXXX ESAO (the European Society for Artificial Organs) Congress
    • Place of Presentation
      グラスゴー イギリス
    • Related Report
      2013 Research-status Report
  • [Presentation] In vivo tissue-engineered small diameter "biotube".2013

    • Author(s)
      K Kanda, T Watanabe, M Yamanami, O Sakai, H Yaku, Y Nakayama.
    • Organizer
      27th EACTS (the European Association for Cardio-Thoracic Surgery)
    • Place of Presentation
      ウィーン オーストリア
    • Related Report
      2013 Research-status Report
  • [Presentation] ビーグル犬の頸動脈へ移植後5年経過したBiotube人工血管の超音波検査による血流評価2013

    • Author(s)
      渡辺太治
    • Organizer
      第12回日本再生医療学会総会
    • Place of Presentation
      横浜
    • Related Report
      2012 Research-status Report
  • [Presentation] Long Term Patency and Durability of in vivo tissue engineered autologous tube grafts "Biotubes"2013

    • Author(s)
      渡辺太治
    • Organizer
      The 62nd International Congress of the European Society for Cardiovascular and Endovascular Surgery (ESCVS)
    • Place of Presentation
      ドイツ(レーンスグルグ)
    • Related Report
      2012 Research-status Report
  • [Presentation] バイオチューブを用いた冠動脈バイパス術-ブタでの予備的異種移植実験2012

    • Author(s)
      渡辺太治
    • Organizer
      第50回日本人工臓器学会大会
    • Place of Presentation
      福岡
    • Related Report
      2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi