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Development of a novel diagnostic tool for pediatric febrile illness using nuclear magnetic resonance spectroscopy

Research Project

Project/Area Number 24659795
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Emergency medicine
Research InstitutionKyoto University

Principal Investigator

KOIKE Kaoru  京都大学, 医学研究科, 教授 (10267164)

Co-Investigator(Kenkyū-buntansha) HIRAKAWA Keiko  日本医科大学, 医学部, 助教 (30165162)
Co-Investigator(Renkei-kenkyūsha) NISHIYAMA Kei  京都大学, 医学(系)研究科(研究院), 講師 (90447970)
ASANO Takeshi  日本医科大学, 医学部, 准教授 (70277490)
OHNO Youkichi  日本医科大学, 医学(系)研究科(研究院), 教授 (70152220)
FUJINO Osamu  日本医科大学, 医学部, 教授 (50173448)
Project Period (FY) 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywords核磁気共鳴法 / 診断 / パターン認識 / 急性脳症 / 髄液
Research Abstract

We have developed a new signal processing technique that comprehensively handles the signal of electromagnetic waves, such as that of nuclear magnetic resonance obtained from complex mixture. In children, it is difficult to distinguish "febrile seizure" from "acute encephalopathy" in the early phase. Our technique demonstrated the capability of identifying one from the other in such cases. We could also separate bacterial and viral meningitis using the same method. The proposed technology is suitable for applications such as blood, urine, cell and internal organ analysis, and we plan to develop it as a novel diagnostic tool for various medical conditions.

Report

(2 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (4 results)

All 2013 2012

All Presentation (2 results) Patent(Industrial Property Rights) (2 results)

  • [Presentation] 複雑な混合物における変化や異常の検出を可能とする新規診断技術2013

    • Author(s)
      小池 薫
    • Organizer
      BIOtech 2013 第12回 国際バイオテクノロジー展/技術会議 アカデミックフォーラム
    • Place of Presentation
      東京ビッグサイト(東京)
    • Related Report
      2012 Final Research Report
  • [Presentation] 複雑な混合物における変化や異常の検出を可能とする新規診断技術2013

    • Author(s)
      小池 薫
    • Organizer
      BIOtech 2013 第12回 国際バイオテクノロジー展/技術会議 アカデミックフォーラム
    • Place of Presentation
      東京ビッグサイト
    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] 混合物試料の属性を識別する方法及び装置2012

    • Inventor(s)
      小池薫・平川慶子・大野曜吉・浅野健・森山剛・森川秀行・村木秀樹
    • Industrial Property Rights Holder
      京都大学・日本医科大学・東京工芸大学・株式会社ユニフローズ
    • Industrial Property Number
      2012-157593
    • Filing Date
      2012-07-13
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 混合物試料の属性を識別する方法及び装置2012

    • Inventor(s)
      小池薫・平川慶子・大野曜吉・浅野健・森山剛・森川秀行・村木秀樹
    • Industrial Property Rights Holder
      京都大学・日本医科大学・東京工芸大学・株式会社ユニフローズ
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012
    • Related Report
      2012 Annual Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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