The development of new available autoimmune marker of Sjogren's syndrome for confirmed diagnosis and prognosis
| Project/Area Number |
24659839
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | The University of Tokushima |
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Principal Investigator |
ARAKAKI Rieko 徳島大学, ヘルスバイオサイエンス研究部, 助教 (00193061)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 自己免疫疾患 / シェーグレン症候群 / 自己免疫マーカー / 確定診断 / 予後診断 / 自己免疫疾患モデルマウス |
|---|
| Research Abstract |
Autoimmune diseases occur due to autoimmune responses of an individual to self-antigens by the disturbance of self-tolerance. The autoimmune disease patients are increasing year by year, and the QOL decreases in the autoimmune diseases patients all over the world. However the diagnostic method based on an etiology of autoimmune disease has not been established. We have studied for mechanism of the onset of Sjogren`s syndrome experimental model mice and serum, saliva and tear sample of the patients. We analyze the precise mechanism of the onset of Sjogren`s syndrome, and developed the new available autoimmune marker for diagnosis and prognosis.
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Report
(3 results)
Research Products
(49 results)
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[Journal Article] Fas-Independent T-Cell Apoptosis by Dendritic Cells Controls Autoimmune Arthritis in MRL/lpr Mice2012
Author(s)
Takashi Izawa, Tomoyuki Kondo, Mie Kurosawa, Ritsuko Oura, Kazuma Matsumoto, Eiji Tanaka, Akiko Yamada, Rieko Arakaki, Yasusei Kudo, Yoshio Hayashi and Naozumi Ishimaru
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Journal Title
PLoS ONE
Volume: Vol.7, No.12
Issue: 12
Pages: e48798-e48798
DOI
NAID
Related Report
Peer Reviewed
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[Presentation] In vivo effect of multi-wall carbon nanotubes on immune system2013
Author(s)
Yamada Koichi, Akihiko Iwasa, Tomoyuki Kondo, Mie Kurosawa, Rieko Arakaki, Akiko Yamada, Yasusei Kudo, Y Taquahashi, A Takagi, J Kanno and Naozumi Ishimaru
Organizer
6th International Symposium on Nanotechnology,Occupational and Environmental system
Place of Presentation
名古屋国際会議場（ 愛知県名古屋市）
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