| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
|
|---|
| Research Abstract |
In this study, we tried to clarify the mechanism of unloading-induced bone loss in some sort by mechano-biological method using simulated microgravity machine. Murine gingival epithelial cell line, GE1, were cultured in both groups ,control (1G) group and micro gravity (CL) group. Cells were cultured continuously for 10 days and sampling were done on days 0, 3, 5, 7, 10, each taking 3 samples from each group. In result, CL group demonstrated inhibition of cell proliferation to half of that of 1G group. Also, morphological differences were suggested since cells in the 1G group were observed flat in uniform surface while cells in the CL group showed distinct cell boundary.
|
