| Project/Area Number |
24659878
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Kagoshima University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MURATA Hiroshi 長崎大学, 大学院医歯薬学総合研究科, 教授 (40229993)
SUEHIRO Fumio 長崎大学, 大学院医歯薬学総合研究科, 助教 (40524781)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 骨造成 / 骨増生 / 骨膜挙上 / 骨膜 / 再生医学 |
|---|
| Research Abstract |
Alveolar ridge tends to absorb by periodontal diseases or aging, and its augmentation technique is required in many cases before dental implantation. However alveolar ridge augmentation is not an easy surgery. The purpose of this study was to evaluate the best material or method to reserve a required space for periosteum augmentation. We used PLLA/PLGA membrane as the periosteum lifting auto-swelling material on rat calvaria model. As a temporary insertion usage, the membrane should be removed within 3 weeks before its self resorption. Interestingly, ectopic bone formations in the PLLA/PLGA membrane were observed after 9 week. Insertion of PLLA/PLGA membrane underneath the periosteum might be an alternative method for alveolar ridge augmentation.
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