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A new gustatory test using molecular analysis of the taste cells.

Research Project

Project/Area Number 24659931
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Social dentistry
Research InstitutionTohoku University

Principal Investigator

TAKASHI Sasano  東北大学, 歯学研究科(研究院), 教授 (10125560)

Co-Investigator(Kenkyū-buntansha) SATOH-KURIWADA Shizuko  東北大学, 大学院歯学研究科, 助教 (60225274)
SHOJI Noriaki  東北大学, 病院, 講師 (70250800)
IIKUBO Masahiro  東北大学, 大学院歯学研究科, 講師 (80302157)
Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords味覚障害 / 味覚検査 / 味覚受容体 / 味覚受容体遺伝子解析
Research Abstract

First, we developed a clinical umami sensitivity test using an umami substance (MSG). In this method, we obtained cutoff point which discriminate normal or disorder taste sensitivity. Next, we develop an objective taste test based on expression analysis of the umami receptor genes in the human tongue by scraping the mucosa on the foliate papillae of the tongue.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (24 results)

All 2014 2013 2012 Other

All Journal Article (12 results) (of which Peer Reviewed: 8 results) Presentation (11 results) (of which Invited: 3 results) Book (1 results)

  • [Journal Article] 特別企画元気な高齢者になろう : 高齢者の健康を支える2013

    • Author(s)
      笹野高嗣
    • Journal Title

      「うま味」感覚FOOD STYLE 21食品化学新聞社

      Volume: 17(4) Pages: 49-52

    • Related Report
      2013 Final Research Report
  • [Journal Article] G.I Research特集/消化管栄養センサ-研究の新展開2013

    • Author(s)
      笹野高嗣佐藤しづ子庄司憲明
    • Journal Title

      うま味感覚の重要性とうま味障害について.先端医学社

      Volume: 21(2) Pages: 126-131

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 口腔機能特集味覚障害を疑おう!2013

    • Author(s)
      笹野高嗣
    • Journal Title

      歯科衛生士クインテッセンス出版株式社

      Volume: 37(2) Pages: 69-75

    • Related Report
      2013 Final Research Report
  • [Journal Article] Important Role of Umami Taste Sensitivity in Oral and Overall Health.2013

    • Author(s)
      Sasano T, Satoh-Kuriwada S, Shoji N, Iikubo M, Kawai M, Uneyama H, Sakamoto M.
    • Journal Title

      Curr Pharm Des.

      Volume: 26 Pages: 20-28

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 高齢者におけるうま味異常感が食品摂取、食欲および体調に及ぼす影響―口腔疾患との関連―2013

    • Author(s)
      佐藤しづ子、金田直人、酒井梓、 金田敏夫、遠藤雄、熊坂晃、嶋田雄介、
    • Journal Title

      日本口腔診断学雑誌

      Volume: 26 Pages: 280-288

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] うま味感覚の重要性とうま味障害について2013

    • Author(s)
      笹野高嗣 佐藤しづ子 庄司憲明
    • Journal Title

      先端医学社

      Volume: 21 Pages: 49-52

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 「食と脳」うま味障害のはなし2012

    • Author(s)
      笹野高嗣
    • Journal Title

      臨床家のための矯正イヤ-ブック、クインテッセンス出版株式会社

    • Related Report
      2013 Final Research Report
  • [Journal Article] 歯科からのアプロ-チ味覚障害と食育2012

    • Author(s)
      笹野高嗣
    • Journal Title

      アポロニア^<21>、日本歯科新聞社

      Pages: 58-63

    • Related Report
      2013 Final Research Report
  • [Journal Article] 味覚障害に対する口腔内科医療の取り組み2012

    • Author(s)
      笹野高嗣
    • Journal Title

      小児歯科臨床、医歯薬出版株式会社

      Volume: 17 Pages: 20-25

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of umami taste sensitivity.2012

    • Author(s)
      Satoh-Kuriwada S, Kawai M, Shoji N, Sekine Y, Uneyama H, Sasano T
    • Journal Title

      J. Nutrition & Food Science

      Volume: 1 Issue: S10

    • DOI

      10.4172/2155-9600.s10-003

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Incidence of taste disorder and umami taste disorder among the Japanese elderly and youth2012

    • Author(s)
      Takashi Sasano, Shizuko Satoh-Kuriwada, Naoto Kaneta, Noriaki Shoji, Misako Kawai and Hisayuki Uneyama
    • Journal Title

      Journal of Nutrition & Food Sciences

      Volume: 01 Issue: S10

    • DOI

      10.4172/2155-9600.s10-002

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Assessment of umami taste sensitivity.2012

    • Author(s)
      Shizuko Satoh-Kuriwada, Misako Kawai, Noriaki Shoji, Yuki Sekine, Hisayuki Uneyama and Takashi Sasano
    • Journal Title

      Journal of Nutrition & Food Sciences

      Volume: 10 Pages: 6-9

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 味覚反射を応用したドライマウス治療への挑戦2013

    • Author(s)
      笹野高嗣
    • Organizer
      日本味と匂学会第47回大会
    • Place of Presentation
      仙台
    • Year and Date
      2013-09-21
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Sasano.Assessment of umami taste sensitivity2013

    • Author(s)
      Shizuko Satoh-Kuriwada, Misako Kawai, Noriaki Shoji, Yuki Sekine, Hisayuki Uneyama and Takashi
    • Organizer
      Assessment of umami taste sensitivity. 9th Asia Pacific Conference on Clinical Nutrition
    • Place of Presentation
      Tokyo
    • Year and Date
      2013-06-21
    • Related Report
      2013 Final Research Report
  • [Presentation] シンポジウム「味覚(うま味)と口腔保健より健康な生活を目指して」味覚障害に対する口腔内科学的診断と治療2013

    • Author(s)
      佐藤しづ子
    • Organizer
      第18回うま味研究会公開シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2013-05-20
    • Related Report
      2013 Final Research Report
  • [Presentation] 味覚障害に対する口腔内科学的診断と治療2013

    • Author(s)
      笹野高嗣
    • Organizer
      第86回日本薬理学会
    • Year and Date
      2013-03-23
    • Related Report
      2013 Final Research Report
  • [Presentation] 高齢者における「うま味」感受性と健康の関連2013

    • Author(s)
      笹野高嗣
    • Organizer
      日本学術振興会産学協力研究委員会レドックス・ライフイノベ-ション第170委員会.第5回レドックス・ライフイノベ-ションシンポジウム
    • Place of Presentation
      川崎
    • Year and Date
      2013-03-07
    • Related Report
      2013 Final Research Report
  • [Presentation] 味覚とくに「うま味」感覚の重要性について-命を支え、活き活きと生きるための「うま味」感覚について2012

    • Author(s)
      笹野高嗣
    • Organizer
      第17・18回共催日本摂食・嚥下リハビリテーション学会学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2012-08-03
    • Related Report
      2013 Final Research Report
  • [Presentation] 味覚反射を応用したドライマウス治療の試み2012

    • Author(s)
      笹野高嗣
    • Organizer
      日本薬学会第132年回
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Related Report
      2013 Final Research Report
  • [Presentation] 味覚とくに「うま味」感覚の重要性について-命を支え、活き活きと生きるための「うま味」感覚について2012

    • Author(s)
      笹野高嗣
    • Organizer
      第17・18回共催 日本摂食・嚥下リハビリテーション学会学術大会
    • Place of Presentation
      札幌
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] シンポジウム 「味覚(うま味)と口腔保健:より健康な生活を目指して」

    • Author(s)
      佐藤しづ子
    • Organizer
      第18回うま味研究会公開シンポジウム
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Assessment of umami taste sensitivity.

    • Author(s)
      Shizuko Satoh-Kuriwada, Misako Kawai, Noriaki Shoji, Yuki Sekine, Hisayuki Uneyama and Takashi Sasano
    • Organizer
      9th Asia Pacific Conference on Clinical Nutrition
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 味覚異常感が高齢者の食と栄養摂取に与える影響

    • Author(s)
      佐藤しづ子、金田直人、酒井梓、 金田敏夫、遠藤雄、熊坂晃、嶋田雄介、
    • Organizer
      第26回日本口腔診断学会・第23回日本口腔内科学会合同学術大会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Book] 高齢者の味覚障害に歯科医院を役立てよう!2014

    • Author(s)
      佐藤しづ子、監修:笹野高嗣
    • Publisher
      学建書院
    • Related Report
      2013 Final Research Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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