| Project/Area Number |
24660051
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Community health/Gerontological nurisng
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
Urabe Mie 京都府立医科大学, 医学部, 講師 (00451401)
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| Co-Investigator(Kenkyū-buntansha) |
成本 迅 京都府立医科大学, 医学(系)研究科(研究院), 准教授 (30347463)
加藤 佑佳 京都府立医科大学, 医学(系)研究科(研究院), 助教 (60729268)
松岡 照之 京都府立医科大学, 医学(系)研究科(研究院), 助教 (40636544)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 認知症 / BPSD / 扁桃体 / VBM / 情動 / 非薬物的介入 / 脳画像 |
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| Outline of Final Research Achievements |
To develop nursing care utilizing the emotion of person with dementia, I am
researching brain imaging to clarify evidence of the emotions of Alzheimer's disease (AD). The purpose of this research is to study the relation between the atrophy of the amygdala and its projection area in the brain and Behavioral and Psychological symptoms of dementia (BPSD).The subjects were a group of patients with AD (ADG : 29, 6 males, 23 females : average age; 80.7 years old : average of MMSE, 20 points), and a control group (21, 6 males, 21 females : average age; 74.1 years old : average of MMSE;28 points). I investigated Behavioral and Psychological symptoms of dementia (BPSD) used Neuropsychiatric Inventory－Nursing Home Version (NPI-NH-J).I analyzed brain atrophy used magnetic resonance imaging (3T )and Voxel-Based Morphometry, and compared ADG with control group in each BPSD. The atrophy of amygdala and hippocampus was related with 3 sub-scores of NPI-NH-J (Anxiety, Irritability/Lability, Apathy).
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