Development of a blood glucose sensor using photoacoustic spectroscopy combined with MEMS
Project/Area Number |
24680058
|
Research Category |
Grant-in-Aid for Young Scientists (A)
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Allocation Type | Partial Multi-year Fund |
Research Field |
Medical systems
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Research Institution | Nagaoka University of Technology |
Principal Investigator |
WADAMORI Naoki 長岡技術科学大学, 工学(系)研究科(研究院), 助教 (60303179)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥26,780,000 (Direct Cost: ¥20,600,000、Indirect Cost: ¥6,180,000)
Fiscal Year 2014: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2013: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2012: ¥14,820,000 (Direct Cost: ¥11,400,000、Indirect Cost: ¥3,420,000)
|
Keywords | 光音響分光法 / 非侵襲血糖値計測 / 糖尿病 / マイクロ・ナノデバイス / 非侵襲 / MEMS / 非侵襲計測 / 血糖値 |
Outline of Final Research Achievements |
From the patient’s point of view, it is necessary that glucose-monitoring devices are portable as well as noninvasive. Unlike the sensitivity of conventional absorption spectroscopy, the sensitivity of photoacoustic spectroscopy (PAS) scales inversely with the dimensions. An external laser and a PA cell with a volume of only 4.0 mm3 were used for monitoring a glucose solution contained in a special sample reservoir. We present PA measurements of glucose in aqueous solutions using a sample reservoir that is suitable for investigations of liquid samples, such as native capillary blood, by performing a long-period measurement. Since the apparatus was miniaturized for in situ and continuous measurements, the PA signal showed a stationary state after a few hours through a transient state from each initial value because of the influence of the temperature and pressure variation in the PA cell. The suppression of this influence is a more complicated problem that needs further study.
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Report
(4 results)
Research Products
(5 results)