| Budget Amount *help |
¥27,040,000 (Direct Cost: ¥20,800,000、Indirect Cost: ¥6,240,000)
Fiscal Year 2015: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2013: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2012: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
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| Outline of Final Research Achievements |
Transcranial direct current stimulation (tDCS) is a non-invasive technique of focal brain stimulation which induces human cortical plasticity. However, the optimal parameters of tDCS and its effect on brain activity remain unknown. Here (1) we show that attention enhanced motor cortical plasticity and motor learning induced by tDCS in both healthy volunteers and stroke patients. Therefore, a combined approach of tDCS plus attention might be useful for the control of cortical plasticity and motor learning in stroke patients with motor dysfunction. (2) We combined tDCS with functional magnetic resonance imaging (fMRI) to investigate the effect of tDCS on brain network dynamics, especially the cortico-striatal circuits which is important for motor learning and memory formation. As the result, we did not find any significant effect of tDCS on the activity of the the cortico-striatal circuits. Thus, I speculate that the effect of tDCS might be limited to the cerebral cortex.
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