Development of a metallic iron nanoparticle-based MRI agent
| Project/Area Number |
24681022
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Kyoto University |
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Principal Investigator |
YAMAMOTO Shinpei 京都大学, 物質-細胞統合システム拠点, 助教 (20362395)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥26,390,000 (Direct Cost: ¥20,300,000、Indirect Cost: ¥6,090,000)
Fiscal Year 2014: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Fiscal Year 2013: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Fiscal Year 2012: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
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| Keywords | iron nanoparticles / 鉄ナノ粒子 / 高分子修飾 / Feナノ粒子 |
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| Outline of Final Research Achievements |
Development of a new magnetic resonance imaging agent based on metallic iron nanoparticles was conducted and following results were obtained: (a) successful synthesis of iron oxide-coated metallic iron nanoparticles having a very high saturation magnetization (Ms > 170 emu/g) and excellent stability in air (decrement of Ms during exposure to air is less than 10 % up to 1000 hrs) and (b) successful atom transfer radical graft polymerization of polyethylene glycol monomethacrylate from the nanoparticles, giving dispersion stability and a “stealth” character.
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Report
(4 results)
Research Products
(4 results)
