Practical application of multi-layered metal nano-cups for studies in life sciences
| Project/Area Number |
24681025
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Kanagawa Academy of Science and Technology |
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Principal Investigator |
Kim Hyonchol 公益財団法人神奈川科学技術アカデミー, オンチップ・セロミクスプロジェクト, 研究員 (70514107)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥26,260,000 (Direct Cost: ¥20,200,000、Indirect Cost: ¥6,060,000)
Fiscal Year 2015: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2014: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2013: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2012: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
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| Keywords | ナノ機能材料 / 磁性構造体 / 細胞回収技術 / 細胞精製 |
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| Outline of Final Research Achievements |
A method of size-selective cell separation using hemispherical superparamagnetic particles, "magcups", was developed. Polystyrene spheres were used for templates of the fabrication, magnetic elements were deposited on the spheres by thermal evaporation, the spheres were removed by burning and the hemispherical superparamagnetic metal shells, magcups, were obtained. Target cells were mixed with a set of different sizes of magcups, then, target cells were only captured in magcups having larger diameters than the cells. The collected cells were grown in culture medium without any damage. These results indicate that the developed method can achieve quick, simple and non-invasive target cell separations depending on their sizes.
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Report
(5 results)
Research Products
(21 results)
