| Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2014: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2013: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2012: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
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| Outline of Final Research Achievements |
During vertebrate organogenesis, cells are autonomously gathered and make a functional cell cluster called a cell society. However, even though cells are put together in vitro, cells are not able to generate the cell society. How cell society is generated during organogenesis remains largely unknown. We have used zebrafish organogenesis (for instance, formation of endoderm-derived organs, Kupffer’s vesicles and somites) as a model for cell society formation, and found several factors which are necessary for generating the cell society during organogenesis.
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