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Connectivity-based segmentation of brain regions using probabilistic diffusion tractography

Research Project

Project/Area Number 24689047
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypePartial Multi-year Fund
Research Field Radiation science
Research InstitutionThe University of Tokyo

Principal Investigator

TAKAO HIDEMASA  東京大学, 医学部附属病院, 講師 (10444093)

Project Period (FY) 2012-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2015: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Keywords脳・神経 / MRI
Outline of Final Research Achievements

We performed connectivity-based parcellation of brain regions such as the amygdala, which is a complex structure composed of a heterogeneous group of nuclei and subnuclei, using diffusion-weighted imaging and probabilistic tractography. The subregions of the amygdala were segmented based on the connectivity pattern between the amygdala and other brain regions. As a basis for connectivity-based parcellation, we evaluated the effects of scanning conditions and image correction methods on morphometric and diffusion-weighted imaging.

Report

(6 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (7 results)

All 2015 2014 2013

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (3 results)

  • [Journal Article] Brain morphology is individual-specific information2015

    • Author(s)
      Hidemasa Takao, Naoto Hayashi, Kuni Ohtomo
    • Journal Title

      Magnetic Resonance Imaging

      Volume: 33 Issue: 6 Pages: 816-821

    • DOI

      10.1016/j.mri.2015.03.010

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Brain diffusivity pattern is individual-specific information2015

    • Author(s)
      Hidemasa Takao, Naoto Hayashi, Kuni Ohtomo
    • Journal Title

      Neuroscience

      Volume: 301 Pages: 395-402

    • DOI

      10.1016/j.neuroscience.2015.06.032

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of study design in multi-scanner voxel-based morphometry studies2014

    • Author(s)
      Hidemasa Takao, Naoto Hayashi, Kuni Ohtomo
    • Journal Title

      NeuroImage

      Volume: 84 Pages: 133-140

    • DOI

      10.1016/j.neuroimage.2013.08.046

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of the use of multiple scanners and of scanner upgrade in longitudinal voxel-based morphometry studies2013

    • Author(s)
      Hidemasa Takao, Naoto Hayashi, Kuni Ohtomo
    • Journal Title

      Journal of Magnetic Resonance Imaging

      Volume: 38 Issue: 5 Pages: 1283-1291

    • DOI

      10.1002/jmri.24038

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 拡散画像とサポートベクターマシンによる機械学習に基づく、疾患の自動判別とその評価2015

    • Author(s)
      高尾英正
    • Organizer
      Advanced CT・MR 2015
    • Place of Presentation
      軽井沢プリンスホテル(長野県軽井沢町)
    • Year and Date
      2015-06-06
    • Related Report
      2015 Annual Research Report
  • [Presentation] Effects of the use of multiple scanners and of scanner upgrade in longitudinal voxel-based morphometry and diffusion tensor imaging studies2013

    • Author(s)
      高尾英正
    • Organizer
      European Congress of Radiology (ECR 2013)
    • Place of Presentation
      ウィーン(オーストリア)
    • Year and Date
      2013-03-07
    • Related Report
      2012 Annual Research Report
  • [Presentation] 多施設脳形態研究において施設ごとの症例の偏りが結果に及ぼす影響2013

    • Author(s)
      高尾英正、林直人、大友邦
    • Organizer
      日本医学放射線学会秋季臨床大会
    • Place of Presentation
      名古屋
    • Related Report
      2013 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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