Perioperative glycemic variability in patients with diabetics melitus
| Project/Area Number |
24689059
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Kobe University (2013-2014)
National Cancer Center Japan (2012) |
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Principal Investigator |
EGI Moritoki 神戸大学, 医学部附属病院, 講師 (20423296)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 糖尿病 / 手術 / 集中治療 / 血糖値 / 変動 |
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| Outline of Final Research Achievements |
We included 107 patients required major operation with the presence of diabetes mellitus. The preoperative HbA1c level in this cohort was 7.5±１.5% in average. The perioperative glycemic gap, which is calculated as the difference between the estimated average of preoperative blood glucose levels and time weighted average of postoperative glycemia, was median of -5 (interquartile range -42, 21)mg/dL. There is significant association with the perioperative glycemic gap with the urine 8-iso-ProstaglandinF2α, which is a surrogate of oxidative stress (p=0.002).
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Report
(4 results)
Research Products
(22 results)
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[Journal Article] Diabetic status and the relationship of the 3 domains of glycemic control to mortality in critically ill patients : an international multi-center cohort study2013
Author(s)
Krinsley JS, Egi M, Kiss A, Amin DN, Schuetz P, Maurer PM, Schultz MJ, van Hooijdonk RT, Kiyoshi M, Mackenzie lM, Annane D, Stow P, Nasraway SA, Holewinski S, Holzinger U, Preiser JC, Vincent JL, Bellomo R
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Journal Title
Crit Care
Volume: 17(2)(Epub ahead of print)
Related Report
Peer Reviewed
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