| Budget Amount *help |
¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Outline of Final Research Achievements |
We included 107 patients required major operation with the presence of diabetes mellitus. The preoperative HbA1c level in this cohort was 7.5±１.5% in average. The perioperative glycemic gap, which is calculated as the difference between the estimated average of preoperative blood glucose levels and time weighted average of postoperative glycemia, was median of -5 (interquartile range -42, 21)mg/dL. There is significant association with the perioperative glycemic gap with the urine 8-iso-ProstaglandinF2α, which is a surrogate of oxidative stress (p=0.002).
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