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Toward identifying principles in drug repositioning: analyses of poly-indication drugs

Research Project

Project/Area Number 24700300
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Bioinformatics/Life informatics
Research InstitutionOkayama University (2015)
The University of Tokyo (2012-2014)

Principal Investigator

MORITA Mizuki  岡山大学, 医歯(薬)学総合研究科, 准教授 (00519316)

Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords治療薬 / 適応拡大 / 階層分類
Outline of Final Research Achievements

Aiming at identifying principles and rules allowing drug repositioning, characterizations of all drugs currently prescribed in hospitals in Japan were performed. The following major points were explored in this study: the distribution of diseases that the same drug can be applied to, the distribution of drugs that can be used in the same disease, the characterization of disease combinations that the same drugs can be applied to, and the characterization of drugs that can be applied to many diseases.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (15 results)

All 2015 2014 2013 2012

All Journal Article (5 results) (of which Peer Reviewed: 3 results,  Open Access: 2 results) Presentation (10 results) (of which Invited: 1 results)

  • [Journal Article] Implementation of linked data in the life sciences at BioHackathon 20112015

    • Author(s)
      Aoki-Kinoshita KF et al.
    • Journal Title

      Journal of Biomedical Semantics

      Volume: 6 Issue: 1 Pages: 3-3

    • DOI

      10.1186/2041-1480-6-3

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] BioHackathon series in 2011 and 2012 : penetration of ontology and linked data in life science domains2014

    • Author(s)
      Katayama T, Komiyama Y, et al.
    • Journal Title

      Journal of Biomedical Semantics

      Volume: 5 Issue: 1 Pages: 5-5

    • DOI

      10.1186/2041-1480-5-5

    • Related Report
      2014 Research-status Report 2013 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] マイノリティのための情報処理 -難病支援を題材に-2013

    • Author(s)
      森田瑞樹, 荒牧英治
    • Journal Title

      情報処理

      Volume: 54 Pages: 834-840

    • NAID

      110009585682

    • Related Report
      2013 Research-status Report
  • [Journal Article] 患者と医師が使う言葉の違い -闘病記の医学的な応用に向けて-2013

    • Author(s)
      荒牧英治, 増川佐知子, 宮部真衣, 森田瑞樹
    • Journal Title

      人工知能学会誌

      Volume: 28 Pages: 857-861

    • Related Report
      2013 Research-status Report
  • [Journal Article] Toxygates: Interactive Toxicity Analysis on a Hybrid Microarray and Linked Data Platform2013

    • Author(s)
      Johan Nyström-Persson, Yoshinobu Igarashi, Maori Ito, Mizuki Morita, Noriyuki Nakatsu, Hiroshi Yamada, Kenji Mizuguchi
    • Journal Title

      Bioinformatics

      Volume: 29 Issue: 23 Pages: 3080-3086

    • DOI

      10.1093/bioinformatics/btt531

    • NAID

      130005468755

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Arresting Treatment Patterns for Individual Patients in Clinical Big Data: An Exploratory Procedure2014

    • Author(s)
      Mizuki Morita, Masanori Shiro, Shotaro Akaho, Toshihiro Kamishima, Hideki Asoh, Eiji Aramaki, Koiti Hasida, Takahide Kohro
    • Organizer
      AAAI Spring Symposium 2014
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] NTCIR MedNLP-2: 医療分野の言語処理2013

    • Author(s)
      荒牧英治, 大熊智子, 狩野芳伸, 森田瑞樹
    • Organizer
      インタラクティブ情報アクセスと可視化マイニング研究会(SIG-AM)第5回研究会
    • Place of Presentation
      慶応義塾大学 日吉キャンパス(東京)
    • Related Report
      2013 Research-status Report
  • [Presentation] Overview of the NTCIR-10 MedNLP Task2013

    • Author(s)
      Mizuki Morita, Yoshinobu Kano, Tomoko Ohkuma, Mai Miyabe, Eiji Aramaki
    • Organizer
      The 10th NTCIR Conference (NTCIR-10)
    • Place of Presentation
      国立情報学研究所(東京)
    • Related Report
      2013 Research-status Report
  • [Presentation] MedNLP Track at NII Test Collection for Information Retrieval (NTCIR) 2012-13 and 2013-142013

    • Author(s)
      Mizuki Morita, Yoshinobu Kano, Ohkuma Tomoko
    • Organizer
      ShARe/CLEFeHealth 2013
    • Place of Presentation
      Valencia, Spain
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 医療テキストを対象とした言語処理実装システムとそのデータ構造2013

    • Author(s)
      宮部真衣, 森田瑞樹, 荒牧英治
    • Organizer
      第33回医療情報学連合大会(第14回日本医療情報学会学術大会)
    • Place of Presentation
      神戸ファッションマート(兵庫)
    • Related Report
      2013 Research-status Report
  • [Presentation] Comparing Social Media and Search Activity as Social Sensors for the Detection of Influenza2013

    • Author(s)
      Mizuki Morita, Sachiko Maskawa, Eiji Aramaki
    • Organizer
      5th International Symposium on Language in Biology and Medicine (LBM2013)
    • Place of Presentation
      東京大学 本郷キャンパス(東京)
    • Related Report
      2013 Research-status Report
  • [Presentation] NTCIR-10 “MedNLP” Pilot Task:医療分野の言語処理研究の環境整備に向けて2013

    • Author(s)
      森田瑞樹, 狩野芳伸, 大熊智子, 宮部真衣, 荒牧英治
    • Organizer
      言語処理学会第19回年次大会
    • Place of Presentation
      名古屋大学東山キャンパス, 名古屋市, 愛知
    • Related Report
      2012 Research-status Report
  • [Presentation] 医療分野における言語処理研究の環境整備に向けての提案2012

    • Author(s)
      森田瑞樹, 荒牧英治
    • Organizer
      テキストアノテーションワークショップ
    • Place of Presentation
      国立情報学研究所, 千代田区, 東京
    • Related Report
      2012 Research-status Report
  • [Presentation] ICPC-2コードの普及を志向した入力支援ツールの開発2012

    • Author(s)
      森田瑞樹, 荒牧英治
    • Organizer
      第3回プライマリ・ケア連合学会学術大会
    • Place of Presentation
      福岡国際会議場, 福岡市, 福岡
    • Related Report
      2012 Research-status Report
  • [Presentation] 受診理由のコーディング支援ツールの開発2012

    • Author(s)
      森田瑞樹, 篠原恵美子, 宮部真衣, 荒牧英治
    • Organizer
      第32回医療情報学連合大会
    • Place of Presentation
      朱鷺メッセ, 新潟市, 新潟
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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