Cellular and circuit mechanisms of functional connections between neural populations: possible roles of oscillatory neural activity
| Project/Area Number |
24700312
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neuroscience in general
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Morita Kenji 東京大学, 教育学研究科(研究院), 講師 (60446531)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 大脳皮質 / 振動 / 短期可塑性 / 脊髄 / シナプス / 共振 |
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| Outline of Final Research Achievements |
Possible effects of oscillatory neural activity on the neural transmission have been examined using mathematical models. Specifically, estimation of parameters of a model of short-term synaptic plasticity has been done for corticospinal synapses based on the data in the literature, and synaptic transmission was examined by using spike timings obtained from simulation results of a model of cortical (visual cortex) cell. It was found that average transmission (post-synaptic potential) per pre-synaptic spike can become small when apical tuft dendrites of pre-synaptic cortical cell receive inhibitory inputs that oscillate as a population at the beta frequency compared with the cases where inhibitory inputs oscillate at different frequencies or do not periodically oscillate.
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Report
(5 results)
Research Products
(5 results)
