Mechanism of auditory cortex to store and recall the pattern of sounds analyzed by two photon imaging
Project/Area Number |
24700320
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Neuroscience in general
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Research Institution | Niigata University |
Principal Investigator |
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Project Period (FY) |
2012-04-01 – 2014-03-31
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Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 大脳聴覚野 / 和音 / マウス / 脳機能イメージング / 記憶 / 連想 / 聴覚野 / フラビン蛋白蛍光イメージング / 二光子イメージング / 内側膝状体 / 大脳皮質 / 可塑性 |
Research Abstract |
Harmony is a kind of sounds whose components' frequencies are in relation of an integer ratio. Animals perceive the fundamental frequency (F0) which is the greatest common factor of harmonic sounds even if it does not exist. We observed mouse primary auditory cortex with two photon imaging and flavoprotein fluorescence imaging to investigate the neural mechanism to generate this phenomenon. As a result, it was revealed that the primary auditory cortex works as an associative memory circuit, and F0 is one of the components recalled by an associative memory circuit.
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Report
(3 results)
Research Products
(49 results)