Research of neural network basis for generating spatiotemporal activity patterns of animal locomotion
| Project/Area Number |
24700395
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KOHSAKA Hiroshi 東京大学, 新領域創成科学研究科, 助教 (20431900)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | ニューロン / シナプス / 神経回路 / 遺伝学 / 運動制御 / ショウジョウバエ / 生理学 / 介在神経細胞 / オプトジェネティクス / 光遺伝学 / 運動回路 |
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| Research Abstract |
Each animal moves in a certain speed. Though this observation seems obvious, it is still almost unclear how neural circuits generate speed of animal locomotion. In this study, using a motor circuit of Drosophila larvae as a model system, which is amenable to detailed analyses of neuronal networks, we examined the mechanisms of speed control of the larval locomotion. We found that a subset of interneurons, we named per-IN, regulate speed of locomotion by shortening the duration of motor neuronal activities.
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Report
(3 results)
Research Products
(32 results)
