Functional significance of parasagittal clusters formed by cerebellar Purkinje cells
| Project/Area Number |
24700401
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
YAMADA Yoshiyuki 独立行政法人理化学研究所, 脳科学総合研究センター, 基礎科学特別研究員 (80553685)
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| Project Period (FY) |
2012 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 小脳 / 神経回路 / in vivo / 2光子イメージング / Ca^<2+>イメージング / Ca2+イメージング / 神経生理学 |
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| Research Abstract |
Parasagettal clusters formed by cerebellar Purkinje cells were visualized by fluorescent protein introduced by adenovirus vector, the activity of which were monitored by in vivo Ca^<2+> imaging. Spontaneous activity and sensory responses of Purkinje cells were successfully recorded with a single-cellular resolution and in reference to the parasagittal clusters.
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Report
(3 results)
Research Products
(3 results)
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[Journal Article] Improved detection of electrical activity with a voltage probe based on a voltage-sensing phosphatase2013
Author(s)
Tsutsui, H., Jinno, Y., Tomita, A., Niino, Y., Yamada, Y., Mikoshiba, K., Miyawaki A., and Okamura Y.
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Journal Title
J. Physiol.
Volume: 591
Pages: 4427-37
Related Report
Peer Reviewed
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