Functional significance of parasagittal clusters formed by cerebellar Purkinje cells

Research Project

Project/Area Number	24700401
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Neurophysiology and muscle physiology
Research Institution	The Institute of Physical and Chemical Research
Principal Investigator	YAMADA Yoshiyuki 独立行政法人理化学研究所, 脳科学総合研究センター, 基礎科学特別研究員 (80553685)
Project Period (FY)	2012 – 2013
Project Status	Completed (Fiscal Year 2013)
Budget Amount *help	¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000) Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000) Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords	小脳 / 神経回路 / in vivo / 2光子イメージング / Ca^<2+>イメージング / Ca2+イメージング / 神経生理学
Research Abstract	Parasagettal clusters formed by cerebellar Purkinje cells were visualized by fluorescent protein introduced by adenovirus vector, the activity of which were monitored by in vivo Ca^<2+> imaging. Spontaneous activity and sensory responses of Purkinje cells were successfully recorded with a single-cellular resolution and in reference to the parasagittal clusters.

Report

(3 results)