| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
Towards more accurate estimation of physiological brain function using PET, we developed the methodology SFS-RR (structural and functional synergy for resolution recovery), which improves image quality (both resolution and quantification) of PET image by using Wavelet transform and anatomical/structural information (MRI and brain atlas images). We evaluate the performance of the recovery strategy in the case of the quantification of dopaminegic function in striatal regions. The proposed methodology proved effective in the resolution recovery of small structures of brain [11C]raclopride PET images and the improvement is consistent across the anatomical variability of a simulated population (Shidahara et al, 2012).
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