Analysis of visual functions by neurophysiological methods for evaluation of stress responses
Project/Area Number |
24700451
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Biomedical engineering/Biological material science
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Research Institution | Niigata University |
Principal Investigator |
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Project Period (FY) |
2012-04-01 – 2015-03-31
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Project Status |
Completed (Fiscal Year 2014)
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Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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Keywords | 瞳孔反応 / 自律神経系 / ストレス反応 / サーカディアンリズム / 視覚機能 / 瞳孔 |
Outline of Final Research Achievements |
Autonomic nervous system, which controls pupillary behaviors, might be damaged by stressors. We developed the monitoring methods of the nervous system and the circadian rhythms of several autonomic functions by using pupillary analyses. We used blue (470nm) and red (640nm) light stimuli for inducing of pupillary light responses. The blue light especially stimulates the melanopsin-expressing retinal ganglion cells (mRGCs), which contributes to the coordination of circadian rhythms. The pupillary response to the blue stimulation well correlated with heart rate variations and the response to the red light showed fine correlation with body temperature changes. These pupillary behaviors could be a maker for biological rhythms regulated by autonomic nervous system.
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Report
(4 results)
Research Products
(23 results)
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[Presentation] Spatial patterns of cortical oscillation represent associative memory in the primate medial temporal lobe2014
Author(s)
Adachi K, Kawasaki K, Sawahata H, Matsuo T, Suzuki T, Majima K, Tanigawa H, Iijima A, Kamitani Y, Hasegawa I, Nakahara K
Organizer
Neuro2014
Place of Presentation
横浜
Year and Date
2014-09-11
Related Report
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