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Correlation study of the uncinate fasciculus and memory function of healthy individuals using diffusion tensor tractography

Research Project

Project/Area Number 24700456
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Biomedical engineering/Biological material science
Research InstitutionNara Institute of Science and Technology

Principal Investigator

SATO Tetsuo  奈良先端科学技術大学院大学, 情報科学研究科, 助教 (90362839)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords医用・生体画像 / 拡散テンソルMRI
Research Abstract

Tractography is a procedure that can track and demonstrate the 3D neural tracts of the white matter of the brain. Studying these connections is integral to the understanding of the brain function. Specifically, the uncinate fasciculus (UF), which is the white matter in the human brain, is said to be related to cognitive function. The UF tractography is calculated using diffusion tensor imaging (DTI) parameter. Studies have shown that the DTI parameter of dementia patients is lower than that of healthy individuals. It is also suggested that the DTI parameter of healthy individuals decreases with age. In addition, the WMS-R score, which is indicative of general memory, verbal memory and other cognitive functions, of the elderly are lower than of the young. Thus, in this research, we have investigated the correlation between the DTI parameter of UF and WMS-R score.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (12 results)

All 2014 2013 2012 Other

All Presentation (10 results) Book (2 results)

  • [Presentation] Correlation between Diffusion Tensor Tractography and proton MR spectroscopy in normal controls2014

    • Author(s)
      Tetsuo Sato, Nobuyuki Maruyama, Toru Hoshida, Kotaro Minato
    • Organizer
      35th Annual International Conference of the IEEE EMBS
    • Place of Presentation
      大阪府大阪市
    • Year and Date
      2014-07-04
    • Related Report
      2013 Final Research Report
  • [Presentation] Comparison of Relationships between Two Different White Matter Tracts and Memory Function with Healthy Individuals by Using Diffusion Tensor Tractography2014

    • Author(s)
      Tetsuo Sato, Nobuyuki Maruyama, Toru Hoshida, Kotaro Minato
    • Organizer
      ISMRM 21st Annual Meeting
    • Place of Presentation
      ソルトレイクシティ,米国
    • Year and Date
      2014-04-22
    • Related Report
      2013 Final Research Report
  • [Presentation] Correlation between Diffusion Tensor Tractography and proton MR spectroscopy in normal controls2014

    • Author(s)
      Tetsuo Sato, Nobuyuki Maruyama, Toru Hoshida, Kotaro Minato
    • Organizer
      35th Annual International Conference of the IEEE EMBS
    • Place of Presentation
      Osaka International Convention Center, Osaka, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Comparison of Relationships between Two Different White Matter Tracts and Memory Function with Healthy Individuals by Using Diffusion Tensor Tractography2014

    • Author(s)
      Tetsuo Sato, Nobuyuki Maruyama, Tohru Hoshida, Kotaro Minato
    • Organizer
      ISMRM 21st Annual Meeting
    • Place of Presentation
      Salt Palace Convention Center, Salt Lake City, Utah, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] 記憶機能における前頭側頭神経束とMRスペクトロスコピーの相関2013

    • Author(s)
      密山京太,佐藤哲大,星田徹,丸山信之,湊小太郎
    • Organizer
      電子情報通信学会医用画像研究会
    • Place of Presentation
      沖縄県那覇市
    • Year and Date
      2013-01-24
    • Related Report
      2013 Final Research Report
  • [Presentation] Correlation between Uncinate Fasciculus and Memory Tasks in Healthy Individual using Diffusion Tensor Tractography2012

    • Author(s)
      Tetsuo Sato, Nobuyuki Maruyama, Toru Hoshida and Kotaro Minato
    • Organizer
      34th Annual International Conference of the IEEE EMBS
    • Place of Presentation
      サンディエゴ,米国
    • Year and Date
      2012-08-29
    • Related Report
      2013 Final Research Report
  • [Presentation] Effects comparison of DTI registrations by two different input images on whole brain tractography2012

    • Author(s)
      Tetsuo Sato and Kotaro Minato
    • Organizer
      World Congress on Medical Physics and Biomedical Engineering 2012
    • Place of Presentation
      北京,中国
    • Year and Date
      2012-05-28
    • Related Report
      2013 Final Research Report
  • [Presentation] 記憶機能における前頭側頭神経束とMRスペクトロスコピーの相関

    • Author(s)
      密山 京太, 佐藤 哲大, 星田 徹, 丸山 信之, 湊 小太郎
    • Organizer
      電子情報通信学会医用画像研究会
    • Place of Presentation
      沖縄県那覇市
    • Related Report
      2012 Research-status Report
  • [Presentation] Correlation between Uncinate Fasciculus and Memory Tasks in Healthy Individual using Diffusion Tensor Tractography

    • Author(s)
      Tetsuo Sato, Nobuyuki Maruyama, Toru Hoshida and Kotaro Minato
    • Organizer
      34th Annual International Conference of the IEEE EMBS
    • Place of Presentation
      San Diego, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Effects comparison of DTI registrations by two different input images on whole brain tractography

    • Author(s)
      Tetsuo Sato and Kotaro Minato
    • Organizer
      World Congress on Medical Physics and Biomedical Engineering 2012
    • Place of Presentation
      Beijing, China
    • Related Report
      2012 Research-status Report
  • [Book] 実践医用画像解析ハンドブック2012

    • Author(s)
      佐藤哲大,湊小太郎
    • Publisher
      オーム社
    • Related Report
      2013 Final Research Report
  • [Book] 実践医用画像解析ハンドブック2012

    • Author(s)
      佐藤 哲大, 湊 小太郎
    • Publisher
      オーム社
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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