Development of Crohn's disease diagnosis system based on highly accurate intestine extraction from CT images

• Project/Area Number: 24700494
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Medical systems
• Research Institution: Nagoya University
• Principal Investigator: ODA Masahiro 名古屋大学, 情報科学研究科, 助教 (30554810)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: 医用画像処理 / 診断支援システム / 画像認識 / 画像情報処理 / 病変検出

Outline of Final Research Achievements

I have developed a method for extracting complicated large and small intestines and a method for automatically detect ulcers caused by Crohn’s disease. The shapes of the intestines are selectively visualized by using virtual endoscopic views and cross sectional images. Also, virtual unfolded views are introduced to display complicated shapes of the intestines. Users of the system can easily understand the shape of the intestines by using these views. I have developed a Crohn’s disease computer aided diagnosis system which equips the above functions. Diagnosis using the system is one of the new diagnostic method of Crohn’s disease which can reduce load on patients and medical doctors. The system was evaluated by medical doctors and confirmed effectiveness for diagnosis.

Research Products

• [Journal Article] Automated Ulcer Detection Method from CT Images for Computer Aided Diagnosis of Crohn's Disease (2013)
  • Author(s): Masahiro Oda, Takayuki Kitasaka, Kazuhiro Furukawa, Osamu Watanabe, Takafumi Ando, Hidemi Goto, and Kensaku Mori
  • Journal Title: IEICE Transactions on Information and Systems Volume: E96.D Issue: 4 Pages: 808-818
  • DOI: 10.1587/transinf.E96.D.808
  • NAID: 10031182845
  • ISSN: 0916-8532, 1745-1361
  • Peer Reviewed
• [Presentation] Automated method for reconstructing fragmented luminal regions of intestine (2014)
  • Author(s): Masahiro Oda, Takayuki Kitasaka, Kazuhiro Furukawa, Osamu Watanabe, Takafumi Ando, Yoshiki Hirooka, Hidemi Goto, and Kensaku Mori
  • Organizer: MICCAI 2014 Workshop on Abdominal Imaging: Computational and Clinical Applications
  • Place of Presentation: Massachusetts Institute of Technology, MA, USA
  • Year and Date: 2014-09-14
• [Presentation] 大腸の変形を考慮した磁気式位置センサおよび3次元CT像を用いた大腸内視鏡トラッキング手法の精度向上 (2014)
  • Author(s): 近藤 弘明, 小田 昌宏, 古川 和宏, 宮原 良二, 廣岡 芳樹, 後藤 秀実, 北坂 孝幸, 森 健策
  • Organizer: 第33回日本医用画像工学会大会(JAMIT2014)
  • Place of Presentation: 東京慈恵会医科大学
  • Year and Date: 2014-07-24 – 2014-07-26
• [Presentation] An automated method for connecting separated luminal regions of intestine segmented from CT volumes (2014)
  • Author(s): Masahiro Oda, Takayuki Kitasaka, Kazuhiro Furukawa, Osamu Watanabe, Takafumi Ando, Yoshiki Hirooka, Hidemi Goto, Kensaku Mori
  • Organizer: Computer Assisted Radiology and Surgery (CARS) 2014
  • Place of Presentation: Fukuoka International Convention Center, Fukuoka, Japan
  • Year and Date: 2014-06-25 – 2014-06-28
• [Presentation] Development of marker-free estimation method of colonoscope tip position using electromagnetic sensors and CT volumes (2014)
  • Author(s): Hiroaki Kondo, Masahiro Oda, Kazuhiro Furukawa, Ryoji Miyahara, Yoshiki Hirooka, Hidemi Goto, Takayuki Kitasaka, and Kensaku Mori
  • Organizer: Computer Assisted Radiology and Surgery (CARS) 2014
  • Place of Presentation: Fukuoka International Convention Center, Fukuoka, Japan
  • Year and Date: 2014-06-25 – 2014-06-28
• [Presentation] Diagnosis and Surgical Assistance by Medical Image Processing (2013)
  • Author(s): Masahiro Oda
  • Organizer: ACPR 2013 Tutorial on Pattern Recognition for Medical Augmented Reality Systems
  • Place of Presentation: Loisir Hotel & SPA Tower Naha, Naha, Japan
  • Invited
• [Presentation] Semi-automated Virtual Unfolded View Generation Method of Stomach from CT Volumes (2013)
  • Author(s): Masahiro Oda, Tomoaki Suito, Yuichiro Hayashi, Takayuki Kitasaka, Kazuhiro Furukawa, Ryoji Miyahara, Yoshiki Hirooka, Hidemi Goto, Gen Iinuma, Kazunari Misawa, Shigeru Nawano, and Kensaku Mori
  • Organizer: MICCAI 2013
  • Place of Presentation: Nagoya University, Japan
• [Presentation] Evaluation of automated incision line determination process for unfolded view generation from CT volumes (2013)
  • Author(s): Masahiro Oda, Tomoaki Suito, Yuichiro Hayashi, Gen Iinuma, Koichi Furukawa, Kazunari Misawa, Shigeru Nawano, Takayuki Kitasaka, and Kensaku Mori
  • Organizer: Computer Assisted Radiology and Surgery (CARS) 2013
  • Place of Presentation: Heidelberg Convention Center, Heidelberg, Germany
• [Presentation] Colonoscope tracking method based on line registration using CT images and electromagnetic sensors (2013)
  • Author(s): Masahiro Oda, Burak Acar, Kazuhiro Furukawa, Takayuki Kitasaka, Yasuhito Suenaga, Nassir Navab, and Kensaku Mori
  • Organizer: Computer Assisted Radiology and Surgery (CARS) 2013
  • Place of Presentation: Heidelberg Convention Center, Heidelberg, Germany
• [Presentation] 大腸内視鏡ナビゲーションシステムにおける大腸内視鏡先端位置推定精度評価 (2013)
  • Author(s): 小田 昌宏, 近藤 弘明, 北坂 孝幸, 古川 和宏, 宮原 良二, 廣岡 芳樹, 後藤 秀実, Nassir Navabe, 森 健策
  • Organizer: 第22回日本コンピュータ外科学会大会
  • Place of Presentation: 東京大学工学部
• [Presentation] 展開外力自動決定を用いたCT像からの胃仮想展開生成手法 (2013)
  • Author(s): 小田 昌宏, 水藤 倫彰, 林 雄一郎, 北坂 孝幸, 古川 和宏, 宮原 良二, 廣岡 芳樹, 後藤 秀実, 飯沼 元, 三澤 一成, 縄野 繁, 森 健策
  • Organizer: 第32回日本医用画像工学会大会
  • Place of Presentation: 産業技術総合研究所 臨海副都心産学官連携センター
• [Presentation] Supine and prone registration of the colon for CT colonography based on dynamic programming technique (2013)
  • Author(s): Masahiro Oda, Eiichiro Fukano, Takayuki Kitasaka, Tetsuji Takayama, Hirotsugu Takabatake, Masaki Mori, Hiroshi Natori, Shigeru Nawano, and Kensaku Mori
  • Organizer: SPIE Medical Imaging 2013
  • Place of Presentation: Disney's Coronado Springs Resort, Florida, USA
• [Presentation] 3次元腹部CT像からの腸管潰瘍検出における過検出削減処理の検討 (2012)
  • Author(s): 小田 昌宏, 朝倉 詩穂, 古川 和宏, 北坂 孝幸, 渡辺 修, 安藤 貴文, 後藤 秀実, 森 健策
  • Organizer: 第31回日本医用画像工学会大会(JAMIT2012)
  • Place of Presentation: JA北海道厚生連 札幌厚生病院
• [Presentation] A gastric lymph node detection method from 3D abdominal CT images using a multi-shape and multi-scale ellipsoidal structure detection filter (2012)
  • Author(s): Masahiro Oda, Takayuki Kitasaka, Michitaka Fujiwara, Kazunari Misawa, and Kensaku Mori
  • Organizer: International Journal of Computer Assisted Radiology and Surgery (CARS)
  • Place of Presentation: Palazzo dei Congressi, Pisa, Italy