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Development of real-time tumor tracking algorithm for respiratory gated particle therapy

Research Project

Project/Area Number 24700513
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Medical systems
Research InstitutionNational Institute of Radiological Sciences

Principal Investigator

MORI Shinichiro  独立行政法人放射線医学総合研究所, 重粒子医科学センター, チームリーダー (60415403)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords粒子線治療 / 呼吸性移動
Research Abstract

We developed the realtime tumor tracking algorithm based on the human numeric phantom with intrafractional organ motions. Since real human organ motion is much complex, we improved our algorithm by using several data sets reflected to clinical situation. While radiation exposure to the patient is another major problem in X-ray fluoroscopic imaging because A relative large magnitude of radiation exposure may be necessary to improve tumor tracking calculation accuracy. To overcome this problem, we developed the image processing algorithm to improve quality of fluoroscopic image, as a result, this technique could reduce the magnitude of radiation exposure with prevent the accuracy of tumor tracking.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (10 results)

All 2014 2013 2012

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (8 results) (of which Invited: 4 results)

  • [Journal Article] Amplitude-based gated phase-controlled rescanning in carbon-ion scanning beam treatment planning under irregular breathing conditions using lung and liver 4DCTs2014

    • Author(s)
      Shinichiro Mori, Taku Inaniwa, Takuji Furukawa, Wataru Takahashi, Mio Nakajima, Toshiyuki Shirai, Koji Noda, Shigeo Yasuda, Naoyoshi Yamamoto
    • Journal Title

      Journal of Radiation Research

      Volume: (in press) Issue: 5 Pages: 948-958

    • DOI

      10.1093/jrr/rru032

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Systematic evaluation of four-dimensional hybrid depth scanning for carbon-ion lung therapy2013

    • Author(s)
      Shinichiro Mori, Takuji Furukawa, Taku Inaniwa,Silvan Zenklusen, Minoru Nakao, Toshiyuki Shirai, Koji Noda
    • Journal Title

      Medical Physics

      Volume: 40 Issue: 3 Pages: 317201-18

    • DOI

      10.1118/1.4792295

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 呼吸同期炭素線スキャニング治療にむけて2013

    • Author(s)
      森慎一郎
    • Organizer
      第10回中部放射線治療研究会学術講演会
    • Place of Presentation
      名古屋(日本)
    • Year and Date
      2013-11-02
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Gated carbon-ion scanning beam treatment planning under irregular breathing2013

    • Author(s)
      森慎一郎
    • Organizer
      第106回日本医学物理学会学術大会
    • Place of Presentation
      大阪(日本)
    • Year and Date
      2013-09-18
    • Related Report
      2013 Final Research Report
  • [Presentation] Gated carbon-ion scanning beam treatment planning under irregular breathing2013

    • Author(s)
      森 慎一郎
    • Organizer
      第106回日本医学物理学会学術大会
    • Place of Presentation
      大阪大学コンベンションセンター
    • Related Report
      2013 Annual Research Report
  • [Presentation] 呼吸同期炭素線スキャニング治療にむけて2013

    • Author(s)
      森 慎一郎
    • Organizer
      第10回中部放射線治療研究会学術講演会
    • Place of Presentation
      愛知県名古屋市東京第一ホテル
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 粒子線治療装置におけるIGRTの現状と問題点2012

    • Author(s)
      森慎一郎
    • Organizer
      第103回日本医学物理学会学術大会
    • Place of Presentation
      神奈川(日本)
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] 炭素線スキャニング体幹部治療におけるマーカーレストラッキングの最適化手法2012

    • Author(s)
      天野聖也, 森慎一郎, 中島美緒, 山本直敬, 馬場雅彦, 羽石秀昭
    • Organizer
      第103回日本医学物理学会学術大会
    • Place of Presentation
      神奈川(日本)
    • Related Report
      2013 Final Research Report
  • [Presentation] 炭素線スキャニング体幹部治療におけるマーカーレストラッキングの 最適化手法2012

    • Author(s)
      天野聖也、森慎一郎、中島美緒、山本直敬、馬場雅彦、羽石秀昭
    • Organizer
      第103回日本医学物理学会学術大会
    • Place of Presentation
      神奈川、日本
    • Related Report
      2012 Research-status Report
  • [Presentation] 粒子線治療装置におけるIGRTの現状と問題点2012

    • Author(s)
      森慎一郎
    • Organizer
      第103回日本医学物理学会学術大会
    • Place of Presentation
      神奈川、日本
    • Related Report
      2012 Research-status Report
    • Invited

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Published: 2013-05-31   Modified: 2019-07-29  

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