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Short-term spinal plasticity induced by noninvasive afferent stimlation

Research Project

Project/Area Number 24700520
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionThe University of Tokyo

Principal Investigator

OBATA Hiroki  東京大学, 総合文化研究科, 助教 (70455377)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords可塑性 / 脊髄 / 電気生理学
Research Abstract

The purpose of this research was to investigate changes of input-out properties on human spinal circuits after passive ground stepping (PGS) and electrical nerve stimulation (ENS). PGS on the treadmill was assisted by a robotic driven-gait orthosis. ENS was applied to the common peroneal nerve (CPN) in the right leg. The following three interventions were randomly applied for 30 minutes: PGS alone, ENS alone and the combination of these two types of interventions (PGS+ENS). Before and after these interventions, the soleus H-reflex and disynaptic reciprocal inhibition from the common peroneal nerve to the soleus motoneuron were assessed. The results showed that the amounts of reciprocal inhibition were changed after PGS+ENS. Thus, it was shown that short-term plasticity on spinal circuits can be induced by the combination of afferent inputs from multiple pathways.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (1 results)

All 2013

All Presentation (1 results)

  • [Presentation] The effect of electrical stimulation on spinal reciprocal inhibition during robotic passive stepping in humans2013

    • Author(s)
      Hiroki OBATA, Noritaka KAWASHIMA, Kimitaka NAKAZAWA
    • Organizer
      Society for Neuroscience Annual Meeting
    • Related Report
      2013 Annual Research Report 2013 Final Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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